As part of our organization’s launch, the Pain and Addiction Research Center worked closely with the UCSF Alcohol and Addiction Research Group to host a Pain and Addiction Research Retreat this December, 2019. The retreat featured basic science and clinical research talks by faculty, post-docs, and students, as well as a poster session showcasing the depth and breadth of current research in pain and addiction ongoing at UCSF. You can access the program, speaker presentations, and recordings of the live-stream below. Attendees were asked to complete a post-retreat survey, to help determine the direction and scope of future research gatherings, research proposal working groups, and other collaborations that will drive the work of the Pain and Addiction Research Center forward.
62% of survey respondents generated new ideas for experiments, and 59% of respondents made connections for scientific collaboration as a result of the retreat. 76% of respondents stated that they would participate in a future pain or addiction related research proposal working group. These responses highlight the PARC’s enormous potential to foster the necessary collaborations across disciplines that will generate solutions to some of our nation’s greatest public health challenges.
Access Retreat Recording
Program
Mark Schumacher: Intro PARC Initiative
Daniel Lowenstein: Campus Leadership Perspective
Chris Miaskowski: Chronic Pain and Its Impact
Paula Lum: Addiction and Its Impact
Kelly Knight: Structural Factors Affecting Patients with Co-Morbid Pain and Addiction
Theme 1
Clinician Talk - Case Presentation
Valerie Jackson: Chronic Pain and Clinical Behavior
PI Bench Science Talk
Zhonghui Guan: Chronic Pain Models in Animals
Q&A
Moderator: Jon Levine
Theme 2
Clinician Talk – Case Presentation
D. Andrew Tompkins: The Intersection of Pain and Addiction
Hot Topic Journal Club Presentation
Maggie Waung: Pain Relief – It Feels So Good
PI Bench Science Talk
Elyssa Margolis: A Novel CNS Circuit for Analgesia but Not Positive Reinforcement
Q&A
Moderator: Xiaoke Chen
Post-Doc Pain Poster Preview
Man-Cheung Lee: Microdeletion in a FAAH Pseudogene Identified in a Patient with High Anandamide Concentrations and Pain Insensitivity
Post-Doc Addiction Poster Preview
Jeffrey Moffat: Corticostriatal BDNF Signaling Moderates Alcohol Intake and Habitual Alcohol Seeking
Theme 3
Clinician Talk
Daniel Ciccarone: The Triple Wave Epidemic: Opioids, Heroin and Fentanyl
Clinician Talk – Case Presentation
Howard Kornfeld: Buprenorphine, Analgesia, and Opioid Use Disorder
Graduate Student Poster Preview
Reed Stein (Shoichet Lab): Ultra-Large Library Docking for Novel Ligand Discovery: Applications to the Melatonin and Cannabinoid Receptors
PI Bench Science Talk – Addiction
Damien Jullié: Opioid Receptor Function at the Cellular Level
Q&A
Moderator: Joshua Berke
Theme 4
CTSI – RFA Pilot Grant
Abigail Sidibe: Intersection of Pain and Addiction
Clinician Talk – Case Presentation
Mark Schumacher: Clinical Cases from the Wards: Intractable Neuropathic Pain
Faculty Pain Poster Preview
Kord Kober: Pain–Signaling Pathways in Breast Cancer Survivors with Taxol Induced Peripheral Neuropathy
Translational Talk
Michael Rowbotham: Neuropathic Pain and Opioids: Can Opioids Cause Pain?
Q&A
Moderator: Allan Basbaum
Wrap Up
Howard Fields
Posters
Pain
Kyle Self, Catherine Baxley, Joannalyn Delacruz, Shahrzad Hassanbeigi Daryani, Benjamin Ladd, Karen Seal, Jennifer Manuel, Brian Borsari.
Adaptation of the Motivational Interviewing Skills Code to Predict Opioid Use and Use of Alternative Pain Care Strategies in Veterans.
Lee M-C, Xu Z, Sharma M, Eilers H, Kawamata T, Kober, K, and Schumacher M.
Transcription Factor Sp4 is Required for Hyperalgesic State Persistence and Defines a Nociceptive Transcriptome.
Penny Brennan, PhD.
Life Stressors: Elevations and Disparities among Older Adults with Pain.
Kober, K. M., Conley, Y. P., Schumacher, M., Topp, K., Paul, S. M., Levine, J. D., Miaskowski, C.
Pain Signaling Pathways in Breast Cancer Survivors with Taxol Induced Peripheral Neuropathy.
Gregory Nachtrab, Qian Wang, Manual Mohr, Xiaoke Chen.
Circuit Architecture of Descending Pain Modulation in Mouse.
Clayton H. McClintock, Murray B. Stein, Alan N. Simmons, and Irina A. Strigo.
Mindfulness is Related to Reduced Emotional Distance from Others and Chronic Pain Among Interpersonal Trauma Survivors.
Tia A. Tummino, Brian K. Shoichet, & Dave R. Kokel.
Merging target and phenotypic drug discovery approaches to identify novel modulators of central nervous system pain targets.
Elizabeth Bruns MS MD(1), Deanna Beafus PhD(2), Barbara Wismer MD MPH(3), Kelly Knight PhD(1), Shelley Adler PhD(4), Maria Chao MPA DrPH(4).
1University of California, San Francisco, 2 School of Medicine, Wake Forest, 3San Francisco Department of Public Health, 4Osher Center for Integrative Medicine, University of California, San Francisco, CA.
"Out of a Dark Hole" - The Psychosocial (R)evolution of Chronic Pain Experiences of Vulnerable Patients Attending an Integrative Pain Management Program.
Mijung Park PhD MPH RN & Susan Wang MS.
Comorbid Pain and Depression in the Asian American population.
Addiction
Katlin Silm, Jing Yang, Pamela F. Marcott, Cedric S. Asensio, Jacob Eriksen, Daryl A. Guthrie, Amy H. Newman, Christopher P. Ford, Robert H. Edwards.
Synaptic Vesicle Recycling Pathway Determines Neurotransmitter Content and Release Properties.
Alexandra Haas, MFT, Emily Dauria, PhD, D. Andrew Tompkins, MD MHS.
Evaluating the Impact of Project HOUDINI LINK (Hospital Opioid Use Disorder treatment INItiation and LINKage to Care).
Sujatha Sankaran MD, Matt Tierney NP, John Hall MBA, Sirin Tgamol.
A pilot to decrease risk of opioid overdoses in hospitalized patients.
Pain and Addiction
Gadi Gilam, John A. Sturgeon, Dokyoung S. You, Ajay D. Wasan, Beth D. Darnall, and Sean C. Mackey.
Negative Affect–Related Factors Have the Strongest Association with Prescription Opioid Misuse in a Cross-Sectional Cohort of Patients with Chronic Pain.
Joanna R. Sells, Heather Nye, Sarah A. Palyo.
A Proactive Perioperative Approach to Pain and Substance Use in Veterans.
R. Ben-Shalom, J. Balewski, V. Baratham, A. Siththaranjan, H. Kyoung, K. Kim, H. Dong, K. J. Bender, K. E. Bouchard.
Using convolutional neural networks to predict ion channel conductances in neuronal biophysical models.
Damien Jullié, Aaron Marley, Mark von Zastrow.
Differential presynaptic downregulation of opioid receptors.
Speakers
Professor and Chair
Department of Anatomy
Professor in Residence
Department of Neurology
Weill Institute for Neurosciences
Associate Professor
Department of Biology
Stanford University
Professor
Family and Community Medicine
Director, PARC Advisory Panel
Professor Emeritus
Department of Neurology
Weill Institute for Neurosciences
Associate Professor
Department of Anesthesia and Perioperative Care
Pain Psychologist
Pain Management Center
Specialist
Department of Psychiatry
Weill Institute for Neurosciences
Associate Professor,
Department of Anthropology, History, and Social Medicine
School of Medicine
Assistant Professor
Physiological Nursing
Medical Director, Recovery Without Walls
Founding Medical Director, Pain Management and Functional Restoration Clinic, Highland Hospital, Alameda Health Systems, 2010-2017
Clinical Faculty, UCSF School of Medicine, Pain Fellowship Program
Distinguished Fellow, American Society of Addiction Medicine (ASAM)
Anesthesia Research Track Resident (CA2/PGY3)
Department of Anesthesia and Perioperative Care
Core PARC Leader, School of Dentistry
Professor, Oral and Maxillofacial Surgery
Executive Vice Chancellor and Provost
Robert B. and Elinor Aird Professor and Vice Chair
Department of Neurology
Director, Physician-Scientist and Education Training Programs
School of Medicine
Professor of Clinical Medicine
Director, UCSF Primary Care Addiction Medicine Fellowship
Division of HIV, Infectious Diseases and Global Medicine
Department of Medicine
ZSFG
Associate Professor, Neurology
Weill Institute for Neurosciences
Christine Miaskowski, RN, PhD, FAAN
Co-Director, PARC
PARC Core Leader for the School of Nursing
Professor and Vice Chair for Research
American Cancer Society Clinical Research Professor
Sharon Lamb Endowed Chair in Symptom Management Research
Department of Physiological Nursing
Postdoctoral Scholar
Department of Neurology
Weill Institute for Neurosciences
Professor
Division of Pain Medicine
Department of Anesthesia and Perioperative Care
Director of Research
California Pacific Medical Center
Director, PARC
Professor and Chief
Division of Pain Medicine
Department of Anesthesia and Perioperative Care
Program Manager
Clinical and Translational Science Institute
Graduate Student
Shoichet Laboratory
Associate Clinical Professor
Department of Psychiatry
Assistant Professor,
Department of Neurology
Weill Institute for Neuroscience