Overview We are currently investigating the mechanism of neuronal injury and the role of activating transcription factor 3 (ATF3) in SCI. Our study showed ATF3 is one of the most upregulated early response genes after SCI by RNA sequencing and is specifically induced in spinal cord neurons acutely after injury. We are studying the molecular mechanism of ATF3-mediated neuroprotection after SCI by single cell RNA sequencing, and investigating its function in tissue repair and regeneration. In addition, we are also interested in studying the potential of ATF3 as a biomarker for acute central nervous system injuries. Affiliated Lab Pan Lab Principal investigator UCSF Jonathan Pan, PhD, MD Assoc Professor of Anesthesia Collaborators UCSF Zhonghui Guan, MD Professor of Anesthesia Hua Su, MD Professor in Residence Mervyn Maze, MB, CHB Professor External persons Dr. Michael Beattie Professor, Neurological Surgery Dr. Adam Ferguson Professor, Neurological Surgery Dr. Neel Singhal Associate Professor, Neurology Seeking collaborators Do you have an interest in our research and would like to collaborate? If so we would love to hear from you. Email Us Support this research Are you excited by the innovative work we’re doing on this project? Learn how your financial support can make the difference in our work. Support
