Overview This is the study of the effect of anesthetics on neuroinflammatory response and outcomes in SCI. Our recent publication demonstrates the effect of dexmedetomidine (DEX) on modulating neuroinflammation and improving functional recovery after SCI (Gao et al, BJA 2019). We continue to focus on the unique mechanism of anesthetic effect in neurotrauma. Affiliated Lab Pan Lab Research Themes Neurosciences and Pain, Organ Injury in Surgical and Critically Ill Patients Principal investigator UCSF Jonathan Pan, PhD, MD Assoc Professor of Anesthesia Collaborators UCSF Zhonghui Guan, MD Professor of Anesthesia Hua Su, MD Professor in Residence Mervyn Maze, MB, CHB Professor External persons Dr. Michael Beattie Professor, Neurological Surgery Dr. Adam Ferguson Professor, Neurological Surgery Dr. Neel Singhal Associate Professor, Neurology Seeking collaborators Do you have an interest in our research and would like to collaborate? If so we would love to hear from you. Email Us Support this research Are you excited by the innovative work we’re doing on this project? Learn how your financial support can make the difference in our work. Support
Pan Lab Mechanisms of neuronal injury and the role of Activating Transcription Factor 3 (ATF3) in SCI