Our department has long been a national leader in driving the research that ultimately improves the safety and quality of patient care. In fact, we are among the top departments for NIH research funding in anesthesia in the United States. The Research Domain of the Department of Anesthesia and Perioperative Care pursues two basic missions: To advance scientific discovery and innovation in clinically-relevant areas related to anesthesia, perioperative medicine, pain management, and critical care medicine: Our research program is driven by the strength of our faculty, which features some of the most internationally-respected names in anesthesia research. Major research programs in our department focus on anesthetic mechanisms, cognitive outcomes, hypoxia and ischemia, pain, vascular disease, cerebrovascular malformations and stroke, lung injury, sepsis, antibody engineering, data science and bioinformatics, and health equity. To train and develop physicians and scientists pursuing careers that involve basic, translational, and clinical research on topics related to these broad areas: Creation of new knowledge is vital to the future of biomedicine, and our specialty in particular. The department is committed to helping residents, fellows, and junior faculty succeed in identifying and pursuing important research questions. This commitment to scholarship in research runs deep, both historically and in the present, supported wholeheartedly by our Chair, Dr. Gropper, and the entire faculty. Judith Hellman, MDProfessor and Vice Chair of Research