Overview Hereditary Hemorrhagic Telangiectasia (HHT) is an autosomal dominant disorder that causes abnormal blood vessels to form throughout the body. In HHT, small abnormal blood vessels called telangiectasias occur in the skin and mucous membranes, while larger vessel abnormalities, called arteriovenous malformations (AVM), occur in various organs, including the brain, where they can cause bleeding and stroke. Prior data on hemorrhage risk and predictors have primarily come from small single center studies or inferred from sporadic brain AVM studies, which may not accurately reflect risk in HHT patients. Thus, the purpose of this study is to learn more about brain AVMs (BAVMs) and bleeding in HHT. In this multi-center, longitudinal study, we collect data to study risk factors for rupture of BAVMs and also for other bleeding and features of HHT disease, including genetics and imaging characteristics of the BAVMs. For more information about the studyFor more information about HHTTo request a clinic appointment at the UCSF HHT Center of Excellence Affiliated Lab Center for Cerebrovascular Research Principal investigator UCSF Helen Kim, MPH, PhD Professor External persons Marie E. Faughnan, MD, MSc Professor, University of Toronto Director, Toronto HHT Centre Collaborators External persons Steven Hetts, MD Professor, UCSF Co-Director, UCSF HHT Center of Excellence Seeking collaborators Our project is looking for individuals to join our team. Get in touch if you’d like to learn more. Email Us Support this research Are you excited by the innovative work we’re doing on this project? Learn how your financial support can make the difference in our work. Support
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Center for Cerebrovascular Research Investigating disparities and barriers in access to research and care for patients with Hereditary Hemorrhagic Telangiectasia (HHT)
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Center for Cerebrovascular Research Biomarkers of Cerebral Cavernous Angioma with Symptomatic Hemorrhage (CASH)
