Overview Intraoperative neurophysiological monitoring (IONM), particularly using Transcranial Motor Evoked Potentials (TcMEPs), is routinely employed during complex spinal surgeries to safeguard motor pathway integrity. While intravenous magnesium is frequently used as an opioid-sparing adjunct in these cases, its potential effects on TcMEP monitoring remain unclear, with only limited clinical data available. This study proposes a prospective trial to evaluate how varying plasma magnesium levels influence TcMEP signals, addressing a critical gap in both neuromonitoring and magnesium pharmacokinetics in non-pregnant surgical patients. Affiliated Lab Kolodzie Lab Research Themes Population Health and Implementation Sciences, Neurosciences and Pain Principal investigator UCSF Hemra Cil, MD Assistant Clinical Professor Collaborators UCSF Marc Buren, MD Assistant Clinical Professor JP Clark, PhD Manager of Neuromonitoring Kerstin Kolodzie, MD, PhD, MAS Clinical Professor Nancy Sambol, PharmD Associate Professor
Kolodzie Lab Association of the cross-sectional area of the rectus femoris muscle and postoperative outcomes in patients who undergo deceased-donor kidney transplantation
Kolodzie Lab Impact of ozone levels on respiratory complications in pediatric patients undergoing general anesthesia
Kolodzie Lab Does anesthetic technique influence the long-term prognosis for individuals with malignant tumors
