Publications A Physiologically-Based Pharmacokinetic Simulation to Evaluate Approaches to Mitigate Efavirenz-Induced Decrease in Levonorgestrel Exposure with a Contraceptive Implant. Adeojo LW, Patel RC, Sambol NC Population Pharmacokinetic Properties of Piperaquine in Falciparum Malaria: An Individual Participant Data Meta-Analysis. Hoglund RM, Workman L, Edstein MD, Thanh NX, Quang NN, Zongo I, Ouedraogo JB, Borrmann S, Mwai L, Nsanzabana C, Price RN, Dahal P, Sambol NC, Parikh S, Nosten F, Ashley EA, Phyo AP, Lwin KM, McGready R, Day NP, Guerin PJ, White NJ, Barnes KI, Tarning J Population Pharmacokinetics and Pharmacodynamics of Lumefantrine in Young Ugandan Children Treated With Artemether-Lumefantrine for Uncomplicated Malaria. Tchaparian E, Sambol NC, Arinaitwe E, McCormack SA, Bigira V, Wanzira H, Muhindo M, Creek DJ, Sukumar N, Blessborn D, Tappero JW, Kakuru A, Bergqvist Y, Aweeka FT, Parikh S Rethinking Dosing Regimen Selection of Piperaquine for Malaria Chemoprevention: A Simulation Study. Sambol NC, Tappero JW, Arinaitwe E, Parikh S Population Pharmacokinetics of Piperaquine in Young Ugandan Children Treated With Dihydroartemisinin-Piperaquine for Uncomplicated Malaria. Sambol NC, Yan L, Creek DJ, McCormack SA, Arinaitwe E, Bigira V, Wanzira H, Kakuru A, Tappero JW, Lindegardh N, Tarning J, Nosten F, Aweeka FT, Parikh S CYP2A6 genotype but not age determines cotinine half-life in infants and children. Dempsey DA, Sambol NC, Jacob P, Hoffmann E, Tyndale RF, Fuentes-Afflick E, Benowitz NL Enoxaparin thromboprophylaxis in gastric bypass patients: extended duration, dose stratification, and antifactor Xa activity. Borkgren-Okonek MJ, Hart RW, Pantano JE, Rantis PC, Guske PJ, Kane JM, Gordon N, Sambol NC Pharmacokinetics of single-dose levonorgestrel in adolescents. Sambol NC, Harper CC, Kim L, Liu CY, Darney P, Raine TR Plasma pharmacokinetics and tissue biodistribution of boron following administration of a boronated porphyrin in dogs. Tibbitts J, Sambol NC, Fike JR, Bauer WF, Kahl SB Pharmacodynamic analysis of analgesic clinical trials: nonlinear mixed-effects logistic models. Liu CY, Sambol NC Pharmacokinetics and pharmacodynamics of metformin in healthy subjects and patients with noninsulin-dependent diabetes mellitus. Sambol NC, Chiang J, O'Conner M, Liu CY, Lin ET, Goodman AM, Benet LZ, Karam JH Food intake and dosage level, but not tablet vs solution dosage form, affect the absorption of metformin HCl in man. Sambol NC, Brookes LG, Chiang J, Goodman AM, Lin ET, Liu CY, Benet LZ In vitro-in vivo relationship of oral extended-release dosage forms. Liu FY, Sambol NC, Giannini RP, Liu CY Kidney function and age are both predictors of pharmacokinetics of metformin. Sambol NC, Chiang J, Lin ET, Goodman AM, Liu CY, Benet LZ, Cogan MG Felodipine population dose-response and concentration-response relationships in patients with essential hypertension. Wade JR, Sambol NC Pharmacokinetics of oral extended-release dosage forms. I. Release kinetics, concentration, and absorbed fraction. Liu FY, Sambol NC, Giannini RP, Liu CY Pharmacodynamic analysis of analgesic clinical trials using empirical methods. Liu CY, Sambol NC Interaction between structural, statistical, and covariate models in population pharmacokinetic analysis. Wade JR, Beal SL, Sambol NC Variational analysis of the transdermal delivery rate from two prototypical ethanol-water nitroglycerin TTS devices and Transderm-Nitro 10 in the normal population. Kochak GM, Berner B, Leal M, Sambol NC Population dose versus response of betaxolol and atenolol: a comparison of potency and variability. Sambol NC, Sheiner LB Effect of hydrochlorothiazide 25 mg/day on essential hypertension. Sambol NC, Bostrom A, Williams RL Pharmacokinetics, pharmacodynamics, and minimum effective clinical dose of intravenous nicardipine. Cook E, Clifton GG, Vargas R, Bienvenu G, Williams R, Sambol N, McMahon G, Grandy S, Lai CM, Quon C Study designs for dose-ranging. Sheiner LB, Beal SL, Sambol NC A comparison of the influence of famotidine and cimetidine on phenytoin elimination and hepatic blood flow. Sambol NC, Upton RA, Chremos AN, Lin ET, Williams RL Sequential infusions of methotrexate and 5-fluorouracil in advanced cancer: pharmacology, toxicity, and response. Benz C, DeGregorio M, Saks S, Sambol N, Holleran W, Ignoffo R, Lewis B, Cadman E
