Publications A Physiologically-Based Pharmacokinetic Simulation to Evaluate Approaches to Mitigate Efavirenz-Induced Decrease in Levonorgestrel Exposure with a Contraceptive Implant. Adeojo LW, Patel RC, Sambol NC Pharmaceutics . Aug 7, 2024 Population Pharmacokinetic Properties of Piperaquine in Falciparum Malaria: An Individual Participant Data Meta-Analysis. Hoglund RM, Workman L, Edstein MD, Thanh NX, Quang NN, Zongo I, Ouedraogo JB, Borrmann S, Mwai L, Nsanzabana C, Price RN, Dahal P, Sambol NC, Parikh S, Nosten F, Ashley EA, Phyo AP, Lwin KM, McGready R, Day NP, Guerin PJ, White NJ, Barnes KI, Tarning J PLoS medicine . Jan 10, 2017 Population Pharmacokinetics and Pharmacodynamics of Lumefantrine in Young Ugandan Children Treated With Artemether-Lumefantrine for Uncomplicated Malaria. Tchaparian E, Sambol NC, Arinaitwe E, McCormack SA, Bigira V, Wanzira H, Muhindo M, Creek DJ, Sukumar N, Blessborn D, Tappero JW, Kakuru A, Bergqvist Y, Aweeka FT, Parikh S The Journal of infectious diseases . Jul 28, 2016 Rethinking Dosing Regimen Selection of Piperaquine for Malaria Chemoprevention: A Simulation Study. Sambol NC, Tappero JW, Arinaitwe E, Parikh S PloS one . May 16, 2016 Population Pharmacokinetics of Piperaquine in Young Ugandan Children Treated With Dihydroartemisinin-Piperaquine for Uncomplicated Malaria. Sambol NC, Yan L, Creek DJ, McCormack SA, Arinaitwe E, Bigira V, Wanzira H, Kakuru A, Tappero JW, Lindegardh N, Tarning J, Nosten F, Aweeka FT, Parikh S Clinical pharmacology and therapeutics . May 2, 2015 CYP2A6 genotype but not age determines cotinine half-life in infants and children. Dempsey DA, Sambol NC, Jacob P, Hoffmann E, Tyndale RF, Fuentes-Afflick E, Benowitz NL Clinical pharmacology and therapeutics . May 29, 2013 Enoxaparin thromboprophylaxis in gastric bypass patients: extended duration, dose stratification, and antifactor Xa activity. Borkgren-Okonek MJ, Hart RW, Pantano JE, Rantis PC, Guske PJ, Kane JM, Gordon N, Sambol NC Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery . Feb 8, 2008 Pharmacokinetics of single-dose levonorgestrel in adolescents. Sambol NC, Harper CC, Kim L, Liu CY, Darney P, Raine TR Contraception . Jun 16, 2006 Plasma pharmacokinetics and tissue biodistribution of boron following administration of a boronated porphyrin in dogs. Tibbitts J, Sambol NC, Fike JR, Bauer WF, Kahl SB Journal of pharmaceutical sciences . Apr 1, 2000 Pharmacodynamic analysis of analgesic clinical trials: nonlinear mixed-effects logistic models. Liu CY, Sambol NC Journal of biopharmaceutical statistics . May 1, 1999 Pharmacokinetics and pharmacodynamics of metformin in healthy subjects and patients with noninsulin-dependent diabetes mellitus. Sambol NC, Chiang J, O'Conner M, Liu CY, Lin ET, Goodman AM, Benet LZ, Karam JH Journal of clinical pharmacology . Nov 1, 1996 Food intake and dosage level, but not tablet vs solution dosage form, affect the absorption of metformin HCl in man. Sambol NC, Brookes LG, Chiang J, Goodman AM, Lin ET, Liu CY, Benet LZ British journal of clinical pharmacology . Oct 1, 1996 In vitro-in vivo relationship of oral extended-release dosage forms. Liu FY, Sambol NC, Giannini RP, Liu CY Pharmaceutical research . Oct 1, 1996 Kidney function and age are both predictors of pharmacokinetics of metformin. Sambol NC, Chiang J, Lin ET, Goodman AM, Liu CY, Benet LZ, Cogan MG Journal of clinical pharmacology . Nov 1, 1995 Felodipine population dose-response and concentration-response relationships in patients with essential hypertension. Wade JR, Sambol NC Clinical pharmacology and therapeutics . May 1, 1995 Pharmacokinetics of oral extended-release dosage forms. I. Release kinetics, concentration, and absorbed fraction. Liu FY, Sambol NC, Giannini RP, Liu CY Pharmaceutical research . May 1, 1995 Pharmacodynamic analysis of analgesic clinical trials using empirical methods. Liu CY, Sambol NC Pharmaceutical research . Mar 1, 1995 Interaction between structural, statistical, and covariate models in population pharmacokinetic analysis. Wade JR, Beal SL, Sambol NC Journal of pharmacokinetics and biopharmaceutics . Apr 1, 1994 Variational analysis of the transdermal delivery rate from two prototypical ethanol-water nitroglycerin TTS devices and Transderm-Nitro 10 in the normal population. Kochak GM, Berner B, Leal M, Sambol NC Journal of pharmacokinetics and biopharmaceutics . Oct 1, 1992 Population dose versus response of betaxolol and atenolol: a comparison of potency and variability. Sambol NC, Sheiner LB Clinical pharmacology and therapeutics . Jan 1, 1991 Effect of hydrochlorothiazide 25 mg/day on essential hypertension. Sambol NC, Bostrom A, Williams RL Clinical pharmacy . Nov 1, 1990 Pharmacokinetics, pharmacodynamics, and minimum effective clinical dose of intravenous nicardipine. Cook E, Clifton GG, Vargas R, Bienvenu G, Williams R, Sambol N, McMahon G, Grandy S, Lai CM, Quon C Clinical pharmacology and therapeutics . Jun 1, 1990 Study designs for dose-ranging. Sheiner LB, Beal SL, Sambol NC Clinical pharmacology and therapeutics . Jul 1, 1989 A comparison of the influence of famotidine and cimetidine on phenytoin elimination and hepatic blood flow. Sambol NC, Upton RA, Chremos AN, Lin ET, Williams RL British journal of clinical pharmacology . Jan 1, 1989 Sequential infusions of methotrexate and 5-fluorouracil in advanced cancer: pharmacology, toxicity, and response. Benz C, DeGregorio M, Saks S, Sambol N, Holleran W, Ignoffo R, Lewis B, Cadman E Cancer research . Jul 1, 1985