Overview The main hypothesis of this application is that acute cognitive changes after major surgery unmask older patients with Alzheimer’s Disease (AD) pathology that can be detected with plasma markers of neurodegeneration. 3R01NR017622-02S1 Affiliated Lab Perioperative Medicine Research Group Principal investigator UCSF Jacqueline Leung, MD, MPH Professor Emeritus Support this research Are you exited by the innovative work we’re doing on this project? Learn howyour financial support can make the difference in our work. Support