Role Faculty Location Zuckerberg San Francisco General Hospital Category Clinical Research Specialties Trauma Education 07/2011 - Post-doctoral Fellowship/Clinical Instructor, University of California San Francisco07/2009 - Anesthesiology, University of California San Francisco06/2006 - Internship in Internal Medicine, Santa Clara Valley Medical CenterMD/PhD, 06/2005 - Medicine/Immunology, New York University School of MedicineBachelors of Science/Arts, 06/1996 - Chemistry/History, University of Rochester Publications Regulation of Lung Immune Tone by the Gut-Lung Axis via Dietary Fiber, Gut Microbiota, and Short-Chain Fatty Acids Maruyama D, Liao WI, Tian X, Bredon M, Knapp J, Tat C, Doan TNM, Chassaing B, Bhargava A, Sokol H, Prakash A. A Mouse Model of Orotracheal Intubation and Ventilated Lung Ischemia Reperfusion Surgery Liao, W. I., Maruyama, D., Kianian, F., Tat, C., Tian, X., Hellman, J., Dodd-o, J. M., Prakash, A. Lung immune tone via gut-lung axis: gut-derived LPS and short-chain fatty acids' immunometabolic regulation of lung IL-1β, FFAR2, and FFAR3 expression. Liu Q, Tian X, Maruyama D, Arjomandi M, Prakash A Clinical Evaluation of a COVID-19 Antibody Lateral Flow Assay using Point of Care Samples. Lee W, Straube S, Sincic R, Noble JA, Montoy JC, Kornblith AE, Prakash A, Wang R, Bainton RJ, Kurien PA A journey upstream: Fluctuating platelet-specific genes in cell-free plasma as proof-of-concept for using ribonucleic acid sequencing to improve understanding of postinjury platelet biology. Kornblith LZ, Bainton CMV, Fields AT, Matthay ZA, Magid NT, Nunez-Garcia B, Prakash A, Kurien PA, Callcut RA, Cohen MJ, Bainton RJ Corrigendum: Elevated Gut Microbiome-Derived Propionate Levels Are Associated With Reduced Sterile Lung Inflammation and Bacterial Immunity in Mice. Tian X, Hellman J, Horswill AR, Crosby HA, Francis KP, Prakash A Elevated Gut Microbiome-Derived Propionate Levels Are Associated With Reduced Sterile Lung Inflammation and Bacterial Immunity in Mice. Tian X, Hellman J, Horswill AR, Crosby HA, Francis KP, Prakash A NLRP3 Inflammasome Mediates Dormant Neutrophil Recruitment following Sterile Lung Injury and Protects against Subsequent Bacterial Pneumonia in Mice. Tian X, Sun H, Casbon AJ, Lim E, Francis KP, Hellman J, Prakash A N-Arachidonoyl Dopamine Modulates Acute Systemic Inflammation via Nonhematopoietic TRPV1. Lawton SK, Xu F, Tran A, Wong E, Prakash A, Schumacher M, Hellman J, Wilhelmsen K Lung Ischemia-Reperfusion is a Sterile Inflammatory Process Influenced by Commensal Microbiota in Mice. Prakash A, Sundar SV, Zhu YG, Tran A, Lee JW, Lowell C, Hellman J Extracellular signal-regulated kinase 5 promotes acute cellular and systemic inflammation. Wilhelmsen K, Xu F, Farrar K, Tran A, Khakpour S, Sundar S, Prakash A, Wang J, Gray NS, Hellman J Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS. Kangelaris KN, Prakash A, Liu KD, Aouizerat B, Woodruff PG, Erle DJ, Rogers A, Seeley EJ, Chu J, Liu T, Osterberg-Deiss T, Zhuo H, Matthay MA, Calfee CS Enhanced detection of myeloperoxidase activity in deep tissues through luminescent excitation of near-infrared nanoparticles. Zhang N, Francis KP, Prakash A, Ansaldi D Alveolar macrophages and Toll-like receptor 4 mediate ventilated lung ischemia reperfusion injury in mice. Prakash A, Mesa KR, Wilhelmsen K, Xu F, Dodd-o JM, Hellman J Activation of endothelial TLR2 by bacterial lipoprotein upregulates proteins specific for the neutrophil response. Wilhelmsen K, Mesa KR, Prakash A, Xu F, Hellman J Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo. Shin HS, Xu F, Bagchi A, Herrup E, Prakash A, Valentine C, Kulkarni H, Wilhelmsen K, Warren S, Hellman J Editorial: Pattern recognition receptors and factor B: "complement"ary pathways converge. Prakash A, Hellman J Regulation of IRF7 through cell type-specific protein stability. Prakash A, Levy DE Tissue-specific positive feedback requirements for production of type I interferon following virus infection. Prakash A, Smith E, Lee CK, Levy DE Ringing the interferon alarm: differential regulation of gene expression at the interface between innate and adaptive immunity. Levy DE, Marié I, Prakash A Acetylation of interferon regulatory factor-7 by p300/CREB-binding protein (CBP)-associated factor (PCAF) impairs its DNA binding. Caillaud A, Prakash A, Smith E, Masumi A, Hovanessian AG, Levy DE, Marié I Enhancement and diversification of IFN induction by IRF-7-mediated positive feedback. Levy DE, Marié I, Smith E, Prakash A IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein. Smith EJ, Marié I, Prakash A, García-Sastre A, Levy DE Phosphorylation-induced dimerization of interferon regulatory factor 7 unmasks DNA binding and a bipartite transactivation domain. Marié I, Smith E, Prakash A, Levy DE
