See our current research projects Prakash Lab Gut-Lung Axis: Gut microbiome control of lung injury responses in mice and humans Prakash Lab Innate immune mechanisms of lung Ischemia Reperfusion (IR) injury in mice Prakash Lab Human lung tissue biorepository for investigation of lung immune tone Principal Investigator Arun Prakash Budde, MD, PhD Professor in Residence People See all Tomohiro Chaki, MD, PhD Postdoctoral Scholar Thien Doan, MD Postdoctoral Scholar Daisuke Maruyama, MD, PhD Postdoctoral Scholar Selected PublicationsMaruyama D, Tian X, Doan TNM, Liao WI, Chaki T, Taenaka H, Maishan M, Matthay MA, Prakash A; Gut microbiome-derived propionate reprograms alveolar macrophages metabolically and regulates lung injury responses in mice.; Gut microbes; 2025Maruyama D, Doan TNM, Tian X, Chaki T, Yeh JJ, Layden BT, Prakash A; Gut Microbiota-Derived Lipopolysaccharides and Short-Chain Fatty Acids Regulate Immune Responses via FFAR2/FFAR3 in Lung Ischemia-Reperfusion Injury.; Annals of the New York Academy of Sciences; 2025Liu Q, Tian X, Maruyama D, Arjomandi M, Prakash A; Lung immune tone via gut-lung axis: gut-derived LPS and short-chain fatty acids' immunometabolic regulation of lung IL-1β, FFAR2, and FFAR3 expression.; American journal of physiology. Lung cellular and molecular physiology; 2021Tian X, Hellman J, Horswill AR, Crosby HA, Francis KP, Prakash A; Elevated Gut Microbiome-Derived Propionate Levels Are Associated With Reduced Sterile Lung Inflammation and Bacterial Immunity in Mice.; Frontiers in microbiology; 2019Tian X, Sun H, Casbon AJ, Lim E, Francis KP, Hellman J, Prakash A; NLRP3 Inflammasome Mediates Dormant Neutrophil Recruitment following Sterile Lung Injury and Protects against Subsequent Bacterial Pneumonia in Mice.; Frontiers in immunology; 2017 Lab timeline Image Join our team Interested in joining our team? Explore Opportunities Interested in collaborating? Do you have an interest in our research and would like to collaborate? If so we would love to hear from you. Get In Touch Support us Are you excited by the innovative work we’re doing on this project? Learn how your financial support can make the difference in our work. Learn About Donor Impact and Donate
