Biography I'm an experienced clinical-academic anesthesiologist with special expertise in anesthesia for neurosurgery. Research has included both laboratory and clinical with a focus on the interplay of neurosurgery, cerebral ischemia, and anesthetic pharmacology. Current focus is Global Health, specifically the perioperative echo system. Activities include Advocacy, Patient Safety, Metrics, Policy & Standards Role Faculty Category Clinical Specialties Global Health Equity Education 06/1980 - Pulmonary Research, Mayo ClinicFRCPC, 06/1979 - Anesthesia, University of TorontoM.D., 1972 - School of Medicine, University of Capetown Publications Lassen's Cerebral Autoregulation Plot Revisited and Validated 65 Years Later: Impacts of Vasoactive Drug Treatment on Cerebral Blood Flow. Meng L, Sun Y, Rasmussen M, Libiran NBS, Naiken S, Meacham KS, Schmidt JD, Lahiri NK, Han J, Liu Z, Adams DC, Gelb AW Availability of halothane is still important in some parts of the world. Gelb AW, Vreede E Comparison of the Efficacy of HSK3486 and Propofol for Induction of General Anesthesia in Adults: A Multicenter, Randomized, Double-Blind, Controlled, Phase 3 Noninferiority Trial. Gan TJ, Bertoch T, Habib AS, Yan P, Zhou R, Lai YL, Liu X, Essandoh M, Daley WL, Gelb AW The Global Anesthesia Workforce Survey: Updates and Trends in the Anesthesia Workforce. Law TJ, Lipnick MS, Morriss W, Gelb AW, Mellin-Olsen J, Filipescu D, Rowles J, Rod P, Khan F, Yazbeck P, Zoumenou E, Ibarra P, Ranatunga K, Bulamba F, Collaborators Strategic partnerships to improve surgical care in the Asia-Pacific region: proceedings. Qin RX, Stankey M, Jayaram A, Fowler ZG, Yoon S, Watters D, Gelb AW, Park KB Procedure-Related Complications in Sham Surgeries for Parkinson's Clinical Trials: A Meta-analysis. Mamaril-Davis JC, Gelb AW, Larson PS A Cross-Sectional Survey of Anesthetic Airway Equipment and Airway Management Practices in Uganda. Bulamba F, Connelly S, Richards S, Lipnick MS, Gelb AW, Igaga EN, Nabukenya MT, Wabule A, Hewitt-Smith A Anesthesia Care for Cataract Surgery in Medicare Beneficiaries. Perumal D, Dudley RA, Gan S, Boscardin WJ, Gill A, Gelb AW, Lee SJ, Chen CL Correction to: Initiatives to support rural access to anesthesia. Law TJ, Rose J, Gelb AW Effect of Electroencephalography Spectral Edge Frequency (SEF) and Patient State Index (PSI)-Guided Propofol-Remifentanil Anesthesia on Delirium After Laparoscopic Surgery: The eMODIPOD Randomized Controlled Trial. Wang E, Wang L, Ye C, Luo N, Zhang Y, Zhong Y, Zhu M, Zou Y, Li Q, Li L, Song Z, Luo H, Dai F, Liu H, Gelb AW, Guo Q, Meng L, eMODIPOD Research Group Initiatives to support rural access to anesthesia. Law TJ, Rose J, Gelb AW Principles of environmentally-sustainable anaesthesia: a global consensus statement from the World Federation of Societies of Anaesthesiologists. White SM, Shelton CL, Gelb AW, Lawson C, McGain F, Muret J, Sherman JD, representing the World Federation of Societies of Anaesthesiologists Global Working Group on Environ The World Federation of Societies of Anaesthesiologists Minimum Capnometer Specifications 2021-A Guide for Health Care Decision Makers. Gelb AW, McDougall RJ, Gore-Booth J, Mainland PA, WFSA Ad Hoc Capnometry Workgroup Global surgery, obstetric, and anaesthesia indicator definitions and reporting: An Utstein consensus report. Davies JI, Gelb AW, Gore-Booth J, Martin J, Mellin-Olsen J, Åkerman C, Ameh EA, Biccard BM, Braut GS, Chu KM, Derbew M, Ersdal HL, Guzman JM, Hagander L, Haylock-Loor C, Holmer H, Johnson W, Juran S, Kassebaum NJ, Laerdal T, Leather AJM, Lipnick MS, Ljungman D, Makasa EM, Meara JG, Newton MW, Østergaard D, Reynolds T, Romanzi LJ, Santhirapala V, Shrime MG, Søreide K, Steinholt M, Suzuki E, Varallo JE, Visser GHA, Watters D, Weiser TG Postoperative Screening With the Modified National Institutes of Health Stroke Scale After Noncardiac Surgery: A Pilot Study. Flexman AM, Kim CNH, Plyley T, Vila-Rodriguez F, Gelb AW, Field TS Assessment of Anesthesia Capacity in Public Surgical Hospitals in Guatemala. Zha Y, Truché P, Izquierdo E, Zimmerman K, de Izquierdo S, Lipnick MS, Law TJ, Gelb AW, Evans FM Preoperative Medical Testing and Falls in Medicare Beneficiaries Awaiting Cataract Surgery. Chen CL, McLeod SD, Lietman TM, Shen H, Boscardin WJ, Chang HP, Whooley MA, Gelb AW, Lee SJ, Dudley RA Perioperative Care of Patients at High Risk for Stroke During or After Non-cardiac, Non-neurological Surgery: 2020 Guidelines From the Society for Neuroscience in Anesthesiology and Critical Care. Vlisides PE, Moore LE, Whalin MK, Robicsek SA, Gelb AW, Lele AV, Mashour GA Global PRoMiSe (Perioperative Recommendations for Medication Safety): protocol for a mixed-methods study. Nanji KC, Merry AF, Shaikh SD, Pagel C, Deng H, Wahr JA, Gelb AW, Orser BA Impact of capnography on patient safety in high- and low-income settings: a scoping review. Wollner E, Nourian MM, Booth W, Conover S, Law T, Lilaonitkul M, Gelb AW, Lipnick MS Anesthesia for meningioma surgery. Siegmueller C, Maties O, Gelb A Choice of ANesthesia for EndoVAScular Treatment of Acute Ischemic Stroke (CANVAS): Results of the CANVAS Pilot Randomized Controlled Trial. Sun J, Liang F, Wu Y, Zhao Y, Miao Z, Zhang L, Gelb AW, Chan MTV, Peng Y, Han R, CANVAS Pilot Trial Investigators Towards high-quality peri-operative care: a global perspective. Santhirapala V, Peden CJ, Meara JG, Biccard BM, Gelb AW, Johnson WD, Lipnick MS, Makasa EM, Martin J, Maswime S, Mellin-Olsen J, McClain CD The path to safe and accessible anaesthesia care. Law TJ, Lipnick M, Joshi M, Rath GP, Gelb AW Correction to: Global surgery and the World Health Organization: indispensable partners to achieve triple billion goals. Reddy CL, Patterson RH, Caddell L, Gelb AW, Jumbam DT, Romanzi L, Wasserman I, Meara JG Perspectives on Dexmedetomidine Use for Neurosurgical Patients. Lin N, Vutskits L, Bebawy JF, Gelb AW In reply: Clarifying surgery and anesthesia partnerships in response to global surgery and the World Health Organization. Reddy CL, Caddell L, Gelb AW, Jumbam DT, Patterson RH, Romanzi L, Meara JG Knowledge and perceptions about perioperative stroke: a cross-sectional survey of patients scheduled for non-neurologic and non-cardiac surgery. Roughead T, Chui J, Gelb AW, Meng L, Sewell D, Flexman AM Anesthesia Provider Training and Practice Models: A Survey of Africa. Law TJ, Bulamba F, Ochieng JP, Edgcombe H, Thwaites V, Hewitt-Smith A, Zoumenou E, Lilaonitkul M, Gelb AW, Workneh RS, Banguti PM, Bould D, Rod P, Rowles J, Lobo F, Lipnick MS, Global Anesthesia Workforce Study Group Midazolam Sedation Induces Upper Limb Coordination Deficits That Are Reversed by Flumazenil in Patients with Eloquent Area Gliomas. Lin N, Han R, Hui X, Zhang K, Gelb AW Global surgery and the World Health Organization: indispensable partners to achieve triple billion goals. Reddy CL, Patterson RH, Caddell L, Gelb AW, Jumbam DT, Romanzi L, Wasserman I, Meara JG In Reply: Encouraging a Bare Minimum While Striving for the Gold Standard: A Response to the Updated WHO-WFSA Guidelines. Gelb AW, Morriss WW, Johnson W, Merry AF, International Standards for a Safe Practice of Anesthesia Workgroup Perceptions of Perioperative Stroke Among Chinese Anesthesiologists: Starting a Long March to Eliminate This Underappreciated Complication. Meng L, Li J, Flexman AM, Tong C, Zhou X, Gelb AW, Wang T, McDonagh DL The need to collect, aggregate, and analyze global anesthesia and surgery data. Juran S, Gruendl M, Marks IH, Broer PN, Guzman JM, Davies J, Shrime M, Johnson W, Holmer H, Peck G, Makasa E, Hagander L, Klug SJ, Meara JG, Gelb AW, Ljungman D Contributions of academic institutions in high income countries to anesthesia and surgical care in low- and middle-income countries: are they providing what is really needed? Chellam S, Ganbold L, Gadgil A, Orgoi S, Lonnee H, Roy N, Gelb AW The global capnography gap: a call to action. Lipnick MS, Mavoungou P, Gelb AW Blood Pressure Targets in Perioperative Care. Meng L, Yu W, Wang T, Zhang L, Heerdt PM, Gelb AW In reply: Encouraging a bare minimum while striving for the gold standard: a response to the updated WHO-WFSA guidelines. Gelb AW, Morriss WW, Johnson W, Merry AF, International Standards for a Safe Practice of Anesthesia Workgroup Response to: 'Patient blood management in intracranial neurosurgery-do we have sufficient data to define a transfusion threshold?' (Br J Anaesth 2018; 121: 974-76). Kisilevsky A, Gelb AW, Bustillo M, Flexman AM World Health Organization-World Federation of Societies of Anaesthesiologists (WHO-WFSA) International Standards for a Safe Practice of Anesthesia. Gelb AW, Morriss WW, Johnson W, Merry AF, Abayadeera A, Belîi N, Brull SJ, Chibana A, Evans F, Goddia C, Haylock-Loor C, Khan F, Leal S, Lin N, Merchant R, Newton MW, Rowles JS, Sanusi A, Wilson I, Velazquez Berumen A, International Standards for a Safe Practice of Anesthesia Workgroup World Health Organization-World Federation of Societies of Anaesthesiologists (WHO-WFSA) International Standards for a Safe Practice of Anesthesia. Gelb AW, Morriss WW, Johnson W, Merry AF, International Standards for a Safe Practice of Anesthesia Workgroup A Revised Estimate of Costs Associated With Routine Preoperative Testing in Medicare Cataract Patients With a Procedure-Specific Indicator. Chen CL, Clay TH, McLeod S, Chang HP, Gelb AW, Dudley RA Chinese Anesthesiologists Have High Burnout and Low Job Satisfaction: A Cross-Sectional Survey. Li H, Zuo M, Gelb AW, Zhang B, Zhao X, Yao D, Xia D, Huang Y Anaemia and red blood cell transfusion in intracranial neurosurgery: a comprehensive review. Kisilevsky A, Gelb AW, Bustillo M, Flexman AM The Correlation Between Recordable MEPs and Motor Function During Spinal Surgery for Resection of Thoracic Spinal Cord Tumor. Guo L, Li Y, Han R, Gelb AW Anesthesiologists' perception of perioperative stroke risk during non-neurologic and non-cardiac surgery. Sewell D, Gelb AW, Meng L, Chui J, Flexman AM The Need for a Global Perspective on Task-Sharing in Anesthesia. Lipnick MS, Bulamba F, Ttendo S, Gelb AW Erratum to: Access to controlled medicines for anesthesia and surgical care in low-income countries: a narrative review of international drug control systems and policies. Nickerson JW, Pettus K, Wheeler KE, Hallam C, Bewley-Taylor DR, Attaran A, Gelb AW Choice of ANesthesia for EndoVAScular Treatment of Acute Ischemic Stroke: Protocol for a randomized controlled (CANVAS) trial. Peng Y, Li Y, Jian M, Liu X, Sun J, Jia B, Dong J, Zeng M, Lin N, Zhang L, Gelb AW, Chan MT, Han R Anesthesia for awake craniotomy: a how-to guide for the occasional practitioner. Meng L, McDonagh DL, Berger MS, Gelb AW Access to controlled medicines for anesthesia and surgical care in low-income countries: a narrative review of international drug control systems and policies. Nickerson JW, Pettus K, Wheeler KE, Hallam C, Bewley-Taylor DR, Attaran A, Gelb AW The Bare Minimum Requires Caution. Gelb AW, Enright A, Merry AF, Morriss W In Reply. Lin N, Han R, Zhou J, Gelb AW J'agis! Gelb AW, Mainland P, Phillips P, Sharpe P, Kinsella SM, Bailly AL, Jaffe R Effects of Dexmedetomidine on motor- and somatosensory-evoked potentials in patients with thoracic spinal cord tumor: a randomized controlled trial. Li Y, Meng L, Peng Y, Qiao H, Guo L, Han R, Gelb AW Covert stroke after non-cardiac surgery: a prospective cohort study. Mrkobrada M, Hill MD, Chan MT, Sigamani A, Cowan D, Kurz A, Sessler DI, Jacka M, Graham M, Dasgupta M, Dunlop V, Emery DJ, Gulka I, Guyatt G, Heels-Ansdell D, Murkin J, Pettit S, Sahlas DJ, Sharma M, Sharma M, Srinathan S, St John P, Tsai S, Gelb AW, O'Donnell M, Siu D, Chiu PW, Sharath V, George A, Devereaux PJ Recognition and Management of Perioperative Stroke in Hospitalized Patients. Vlisides PE, Mashour GA, Didier TJ, Shanks AM, Weightman A, Gelb AW, Moore LE In Reply. Chui J, Meng L, Gelb AW Definition, evaluation, and management of brain relaxation during craniotomy. Li J, Gelb AW, Flexman AM, Ji F, Meng L Mild Sedation Exacerbates or Unmasks Focal Neurologic Dysfunction in Neurosurgical Patients with Supratentorial Brain Mass Lesions in a Drug-specific Manner. Lin N, Han R, Zhou J, Gelb AW Cerebral ischemia during surgery: an overview. Zhou ZB, Meng L, Gelb AW, Lee R, Huang WQ Outcomes in neuroanesthesia: What matters most? Flexman AM, Meng L, Gelb AW Clinical diagnostic tools for screening of perioperative stroke in general surgery: a systematic review. Sun Z, Yue Y, Leung CC, Chan MT, Gelb AW, Study Group for Perioperative Stroke In China (POSIC) Monitoring cerebral tissue oxygen saturation at frontal and parietal regions during carotid artery stenting. Meng L, Hall M, Settecase F, Higashida RT, Gelb AW Cardiac Output and Cerebral Blood Flow: The Integrated Regulation of Brain Perfusion in Adult Humans. Meng L, Hou W, Chui J, Han R, Gelb AW Awake brain tumor resection during pregnancy: Decision making and technical nuances. Meng L, Han SJ, Rollins MD, Gelb AW, Chang EF The Potential Benefits of Awake Craniotomy for Brain Tumor Resection: An Anesthesiologist's Perspective. Meng L, Berger MS, Gelb AW Motor System Interactions in the Beta Band Decrease during Loss of Consciousness. Swann NC, de Hemptinne C, Maher RB, Stapleton CA, Meng L, Gelb AW, Starr PA Improving perioperative outcomes in low-resource countries: It can't be fixed without data. Weiser TG, Makasa EM, Gelb AW Ketamine: a growing global health-care need. Dong TT, Mellin-Olsen J, Gelb AW Preoperative Testing in Patients Undergoing Cataract Surgery. Chen CL, Gelb AW, Dudley RA A survey of mentorship among Canadian anesthesiology residents. Zakus P, Gelb AW, Flexman AM Preoperative medical testing in Medicare patients undergoing cataract surgery. Chen CL, Lin GA, Bardach NS, Clay TH, Boscardin WJ, Gelb AW, Maze M, Gropper MA, Dudley RA Awake craniotomy in a patient with ejection fraction of 10%: considerations of cerebrovascular and cardiovascular physiology. Meng L, Weston SD, Chang EF, Gelb AW Regulation of cerebral autoregulation by carbon dioxide. Meng L, Gelb AW Patient safety challenges in low-income and middle-income countries. Steffner KR, McQueen KA, Gelb AW Anesthesia management for endovascular treatment. Lee CZ, Gelb AW Perioperative care of patients at high risk for stroke during or after non-cardiac, non-neurologic surgery: consensus statement from the Society for Neuroscience in Anesthesiology and Critical Care*. Mashour GA, Moore LE, Lele AV, Robicsek SA, Gelb AW Lifelong lessons I learned from my resident research project. Gelb AW Flurbiprofen and hypertension but not hydroxyethyl starch are associated with post-craniotomy intracranial haematoma requiring surgery. Jian M, Li X, Wang A, Zhang L, Han R, Gelb AW From the journal archives: cyclopropane: induction and recovery with a bang! Bokoch MP, Gelb AW Reply from the authors. Bilotta F, Gelb AW, Stazi E, Titi L, Paoloni FP, Rosa G Changes in cerebral tissue oxygen saturation during anaesthetic-induced hypotension: an interpretation based on neurovascular coupling and cerebral autoregulation. Meng L, Gelb AW, McDonagh DL Pharmacological perioperative brain neuroprotection: a qualitative review of randomized clinical trials. Bilotta F, Gelb AW, Stazi E, Titi L, Paoloni FP, Rosa G Situation awareness in anesthesia: concept and research. Schulz CM, Endsley MR, Kochs EF, Gelb AW, Wagner KJ Impact of stepwise hyperventilation on cerebral tissue oxygen saturation in anesthetized patients: a mechanistic study. Alexander BS, Gelb AW, Mantulin WW, Cerussi AE, Tromberg BJ, Yu Z, Lee C, Meng L Review article: the role of hypotension in perioperative stroke. Bijker JB, Gelb AW Blood pressure management in stroke. Donovan AL, Flexman AM, Gelb AW The time when hypotension occurs may be important in the management of intraarterial thrombolysis for stroke. Gelb AW, Talke PO Anesthetic management of patients with acute stroke. Flexman AM, Donovan AL, Gelb AW Impact of phenylephrine administration on cerebral tissue oxygen saturation and blood volume is modulated by carbon dioxide in anaesthetized patients. Meng L, Gelb AW, Alexander BS, Cerussi AE, Tromberg BJ, Yu Z, Mantulin WW Preface. Challenges in anaesthesia education. Sullivan KR, Gelb AW Head-up tilt and hyperventilation produce similar changes in cerebral oxygenation and blood volume: an observational comparison study using frequency-domain near-infrared spectroscopy. Meng L, Mantulin WW, Alexander BS, Cerussi AE, Tromberg BJ, Yu Z, Laning K, Kain ZN, Cannesson M, Gelb AW Mentorship in anesthesia: how little we know. Flexman AM, Gelb AW Mentorship in anesthesia. Flexman AM, Gelb AW Perioperative stroke in noncardiac, nonneurosurgical surgery. Ng JL, Chan MT, Gelb AW 2011 Canadian Journal of Anesthesia Guide for Authors. Backman S, Baker A, Beattie S, Brasher P, Bryson G, Cheng D, Crawford M, Deschamps A, Donati F, Drolet P, Gelb AW, Grocott H, Hare G, Hébert P, Karkouti K, Lessard M, Mazer D, de Médicis E, Merry A, Miller DR, Moher D, Morley-Forster P, Plaud B, Preston R, Rashiq S, Sladen R, Tsui B, Werner C, 2011 Editorial Board, Canadian Journal of Anesthesia The use of motor evoked potential monitoring during cerebral aneurysm surgery to predict pure motor deficits due to subcortical ischemia. Guo L, Gelb AW False negatives, muscle relaxants, and motor-evoked potentials. Guo L, Gelb AW Acute and chronic pain following craniotomy. Flexman AM, Ng JL, Gelb AW Perioperative hypothermia (33 degrees C) does not increase the occurrence of cardiovascular events in patients undergoing cerebral aneurysm surgery: findings from the Intraoperative Hypothermia for Aneurysm Surgery Trial. Nguyen HP, Zaroff JG, Bayman EO, Gelb AW, Todd MM, Hindman BJ, IHAST-MIDS and IHAST Investigators Methodology, human factors, and incidence of intraoperative awareness. Errando CL, Pérez-Caballero P, Gelb AW, Sigl JC The long-term effect of four hours of hyperventilation on neurocognitive performance and lesion size after controlled cortical impact in rats. Eberspächer E, Blobner M, Werner C, Ruf S, Eckel B, Engelhard K, Schmahl W, Gelb AW To use or not to use: the dilemma of NSAIDs and craniotomy. Umamaheswara Rao GS, Gelb AW Hyponatremia and subarachnoid hemorrhage: will that be one pinch or two of salt? Bruder N, Ichai C, Gelb AW Independent associations between electrocardiographic abnormalities and outcomes in patients with aneurysmal subarachnoid hemorrhage: findings from the intraoperative hypothermia aneurysm surgery trial. Coghlan LA, Hindman BJ, Bayman EO, Banki NM, Gelb AW, Todd MM, Zaroff JG, IHAST Investigators Hyperventilation--an ill wind that sometimes blows good. Gelb AW, Chan MT Sex and gender in the perioperative period: wake up to reality. Gelb K, Gelb AW The Chinese Society of Anesthesiology: 2007 Annual Meeting report. Wang Y, Gelb AW, Yue Y Does hyperventilation improve operating condition during supratentorial craniotomy? A multicenter randomized crossover trial. Gelb AW, Craen RA, Rao GS, Reddy KR, Megyesi J, Mohanty B, Dash HH, Choi KC, Chan MT The Chinese Society of Anesthesiology: 2006 annual meeting. Wang Y, Jiang L, Guo X, Gelb AW, Yue Y, Chinese Society of Anesthesiology Cardiovascular predictors of in-patient mortality after subarachnoid hemorrhage. Yarlagadda S, Rajendran P, Miss JC, Banki NM, Kopelnik A, Wu AH, Ko N, Gelb AW, Lawton MT, Smith WS, Young WL, Zaroff JG Cerebral blood flow during orthostasis: role of arterial CO2. Serrador JM, Hughson RL, Kowalchuk JM, Bondar RL, Gelb AW Cervical spine motion: a fluoroscopic comparison during intubation with lighted stylet, GlideScope, and Macintosh laryngoscope. Turkstra TP, Craen RA, Pelz DM, Gelb AW Postcraniotomy pain remains a real headache! Talke PO, Gelb AW Relating drug-induced changes in carotid artery mechanics to cardiovagal and sympathetic baroreflex control. O'Leary DD, Steinback CD, Cechetto AD, Foell BT, Topolovec JC, Gelb AW, Cechetto DF, Shoemaker JK Reflex-mediated reduction in human cerebral blood volume. Wilson TD, Shoemaker JK, Kozak R, Lee TY, Gelb AW Venous oxygen embolism produced by injection of hydrogen peroxide into an enterocutaneous fistula. Jones PM, Segal SH, Gelb AW Feedback effects of circulating norepinephrine on sympathetic outflow in healthy subjects. Tulppo MP, Huikuri HV, Tutungi E, Kimmerly DS, Gelb AW, Hughson RL, Mäkikallio TH, Shoemaker JK Propofol neuroprotection in cerebral ischemia and its effects on low-molecular-weight antioxidants and skilled motor tasks. Bayona NA, Gelb AW, Jiang Z, Wilson JX, Urquhart BL, Cechetto DF The comparative effects of desflurane and isoflurane on lumbar cerebrospinal fluid pressure in patients undergoing craniotomy for supratentorial tumors. Kaye A, Kucera IJ, Heavner J, Gelb A, Anwar M, Duban M, Arif AS, Craen R, Chang CT, Trillo R, Hoffman M Postoperative cognitive deficits: more questions than answers. Mackensen GB, Gelb AW Orthostatic hypotension occurs frequently in the first hour after anesthesia. Cowie DA, Shoemaker JK, Gelb AW Circulating norepinephrine and cerebrovascular control in conscious humans. Kimmerly DS, Tutungi E, Wilson TD, Serrador JM, Gelb AW, Hughson RL, Shoemaker JK Remifentanil with morphine transitional analgesia shortens neurological recovery compared to fentanyl for supratentorial craniotomy. Gelb AW, Salevsky F, Chung F, Ringaert K, McTaggart-Cowan RM, Wong T, Manninen PH Detection of awareness in surgical patients with EEG-based indices--bispectral index and patient state index. Schneider G, Gelb AW, Schmeller B, Tschakert R, Kochs E The long-term survival of baboon-to-monkey kidney and liver xenografts. Zhong R, Tucker J, Zhang Z, Wall W, Grant D, Quan D, Garcia B, Gao ZH, Asfar S, Sharpe M, Gelb A, Bailey M, Stiller C The effect of hypothermia on the expression of the apoptosis-regulating protein Bax after incomplete cerebral ischemia and reperfusion in rats. Eberspächer E, Werner C, Engelhard K, Pape M, Gelb A, Hutzler P, Henke J, Kochs E Cold comfort from tepid temperatures. Foell BT, Gelb AW Future challenges for anaesthesia departments. Introduction. Van Aken H, Gelb AW Optimizing an LBNP protocol to test cardiopulmonary and arterial baroreflex control of vascular resistance. Hughson RL, Shoemaker JK, Topor ZL, Edwards MR, O'Leary DD, Lin DC, Gelb AW Propofol anesthesia compared to awake reduces infarct size in rats. Gelb AW, Bayona NA, Wilson JX, Cechetto DF Cerebral blood volume and blood flow responses to hyperventilation in brain tumors during isoflurane or propofol anesthesia. Cenic A, Craen RA, Lee TY, Gelb AW Free radicals, antioxidants, and neurologic injury: possible relationship to cerebral protection by anesthetics. Wilson JX, Gelb AW From which countries do chairpersons and invited speakers at important anaesthesia and intensive care meetings come? Gelb AW Phenylephrine increases cerebral perfusion pressure without increasing intracranial pressure in rabbits with balloon-elevated intracranial pressure. Watts AD, Wyss AJ, Gelb AW Sedative doses of remifentanil have minimal effect on ECoG spike activity during awake epilepsy surgery. Herrick IA, Craen RA, Blume WT, Novick T, Gelb AW Propofol protection of sodium-hydrogen exchange activity sustains glutamate uptake during oxidative stress. Daskalopoulos R, Korcok J, Farhangkhgoee P, Karmazyn M, Gelb AW, Wilson JX The amygdala and cardiovascular control. Cechetto D, Gelb AW Anesthetics and cerebral ischemia--should we continue to dream the impossible dream? Gelb AW, Wilson JX, Cechetto DF Learning fiberoptic intubation on a simple model transfers to the O.R. Naik V, Matsumoto E, Houston P, Hamstra S, Yeung R, Mallon J, Martire T, Zwack RM, Campbell DC, Breen TW, Yip RW, Roy JD, Girard M, Drolet P, Guay J, Bolis RS, LeDez K, Balatbat JT, Mukherji J, Ali MJ, Carroll J, Karski JM, Sui S, Cheng DC, Banner R, Yip R, Zondervan J, Chow V, McMillan D, Fisher J, Lattermann R, Carli F, Wykes L, Schricker T, Mazza L, Carli F, Danjoux G, Thomas D, Lennox PH, Henderson C, Martin L, Mitchell GW, Vaghadia H, Jassal R, Thomson IR, Hudson RJ, McGuire G, Manninen P, El-Beheiry H, Lozano A, Wennberg R, Archer DP, Tang TK, Staveley IR, Goldstein DH, VanDenKerkhof EG, Hall RI, Rocker GM, O'Connor JP, Dunham JI, Mikelberg FS, Dulovic G, Jenkins KL, Correa R, Wong DT, McGuire GP, Fayad AA, Paul J, Yang H, Sawchuk C, Brown KA, Bates JH, Edington R, Pridham J, Mukherji J, Karski JM, Balatbat J, Carroll J, Chun R, Cheng DC, Karski J, DeBrouwere R, Mathieu M, Carroll J, Feindel C, Cheng D, Clairoux M, Coutu S, McCluskey SA, Karkouti K, Ghannam M, Jewett M, Rampersaud R, Yau T, Quirt I, Carver ED, Kim P, Crawford MW, Finley GA, Breau LM, McGrath PJ, Camfield C, Mak PH, Hui TW, Irwin MG, Carli F, Trudel J, Belliveau P, Mayo N, Clunie ML, Crone LL, Klassen LJ, Yip RW, Hubert B, Radomski M, Blaise G, Renzi PM, Paradis MC, Martin R, Parent M, Parent P, Gagnon D, Tétrault JP, Prabhu AJ, Philip BK, Higgins PP, Blanshard HJ, van Rensselaer S, Chung FF, Caraiscos VB, MacDonald JF, Orser BA, Schreiber M, Georgieff M, Jin F, Chung F, Tong D, Reiz JL, Harsanyi Z, Miceli PC, Darke AC, Roy JS, St-Pierre J, Norman PH, Daley MD, Turner KE, Parlow JL, Tod DA, Avery ND, Nicole PC, Trépanier CA, Lessard MR, Marcoux S, Cowie DA, Gelb AW, Shoemaker JK, Baskett R, Lim BC, Dangor A, Morgan PJ, Cleave-Hogg D, Doyle DJ, Byrick R, Filipovi D, Cashin F, Chiu M, Kemp TJ, Bryson GL, Cleland MJ, Crosby ET, Harioka T, Nomura K, Ando N, Ikegami N, Aoki T, Maltby JR, Beriault MT, Watson NC, Liepert DJ, Fick GH, Maltby JR, Liepert D, Prabhu AJ, Correa RK, Wong DT, Chung F, Goyagi T, Bhardwaj A, Hum PD, Traystman RD, Kirsch JR, Bainbridge DT, Swaminathan M, McCreath BJ, Djaiani G, Grocott HP, Day F, Karski J, Djaiani G, Tan J, Cheng D, Wake PJ, Ali M, Karski J, Sui S, Guenther C, Mullen J, Bentley M, Koshal A, Finegan B, Murtha W, Fredrickson MJ, Luginbuehl IA, Bissonnette B, Granton JT, Platt H, Craen RA The effects of propofol in the area postrema of rats. Cechetto DF, Diab T, Gibson CJ, Gelb AW Anesthetic concentrations of propofol protect against oxidative stress in primary astrocyte cultures: comparison with hypothermia. Peters CE, Korcok J, Gelb AW, Wilson JX Monitoring cerebral perfusion after subarachnoid hemorrhage using CT. Nabavi DG, LeBlanc LM, Baxter B, Lee DH, Fox AJ, Lownie SP, Ferguson GG, Craen RA, Gelb AW, Lee TY Perfusion mapping using computed tomography allows accurate prediction of cerebral infarction in experimental brain ischemia. Nabavi DG, Cenic A, Henderson S, Gelb AW, Lee TY Cerebral blood volume and blood flow at varying arterial carbon dioxide tension levels in rabbits during propofol anesthesia. Cenic A, Craen RA, Howard-Lech VL, Lee TY, Gelb AW Anesthesia for temporal lobe epilepsy surgery. Herrick IA, Gelb AW Glutamate stimulates ascorbate transport by astrocytes. Wilson JX, Peters CE, Sitar SM, Daoust P, Gelb AW A CT method to measure hemodynamics in brain tumors: validation and application of cerebral blood flow maps. Cenic A, Nabavi DG, Craen RA, Gelb AW, Lee TY Rate of change of cerebral blood flow velocity with hyperventilation during anesthesia in humans. Chong KY, Craen RA, Murkin JM, Lee D, Eliasziw M, Gelb AW Effect of beta-adrenoreceptor blockade with nadolol on the duration of local anesthesia. Zhang C, Banting DW, Gelb AW, Hamilton JT The effect of sevoflurane and isoflurane anesthesia on interictal spike activity among patients with refractory epilepsy. Watts AD, Herrick IA, McLachlan RS, Craen RA, Gelb AW CT assessment of cerebral perfusion: experimental validation and initial clinical experience. Nabavi DG, Cenic A, Craen RA, Gelb AW, Bennett JD, Kozak R, Lee TY Quantitative assessment of cerebral hemodynamics using CT: stability, accuracy, and precision studies in dogs. Nabavi DG, Cenic A, Dool J, Smith RM, Espinosa F, Craen RA, Gelb AW, Lee TY Rats show unimpaired learning within minutes after recovery from single bolus propofol anesthesia. Engeland CG, Vanderwolf CH, Gelb AW Propofol prevents peroxide-induced inhibition of glutamate transport in cultured astrocytes. Sitar SM, Hanifi-Moghaddam P, Gelb A, Cechetto DF, Siushansian R, Wilson JX Diffusing capacity limitations of the extent of lung volume reduction surgery in an animal model of emphysema. Chen JC, Serna DL, Brenner M, Powell LL, Huh J, McKenna R, Fischel RJ, Gelb A, Monti J, Burney T, Gaon MD, Aryan H, Wilson A Cerebral blood volume measurements using dynamic contrast-enhanced x-ray computed tomography: application to isoflurane anaesthetic studies. Howard-Lech VL, Lee TY, Craen RA, Gelb AW Postoperative myocardial infarction (PMI) after noncardiac surgery. Badner NH, Gelb AW Dynamic CT measurement of cerebral blood flow: a validation study. Cenic A, Nabavi DG, Craen RA, Gelb AW, Lee TY Mechanisms of brain injury and potential therapies. Gelb AW Mild hypothermia as a protective therapy during intracranial aneurysm surgery: a randomized prospective pilot trial. Hindman BJ, Todd MM, Gelb AW, Loftus CM, Craen RA, Schubert A, Mahla ME, Torner JC Propofol and hyperventilation for the treatment of increased intracranial pressure in rabbits. Watts AD, Eliasziw M, Gelb AW Effect of nitrous oxide on cerebral blood flow velocity after induction of hypocapnia. Watts AD, Luney SR, Lee D, Gelb AW Myocardial infarction after noncardiac surgery. Badner NH, Knill RL, Brown JE, Novick TV, Gelb AW Comparison of the Bullard and Macintosh laryngoscopes for endotracheal intubation of patients with a potential cervical spine injury. Watts AD, Gelb AW, Bach DB, Pelz DM Magnesium deficiency increases ketamine sensitivity in rats. Orser B, Smith D, Henderson S, Gelb A Patient-controlled sedation using propofol during interventional neuroradiologic procedures. Herrick IA, Gelb AW, Tseng PS, Kirkby J Propofol sedation during awake craniotomy for seizures: electrocorticographic and epileptogenic effects. Herrick IA, Craen RA, Gelb AW, McLachlan RS, Girvin JP, Parrent AG, Eliasziw M, Kirkby J Propofol sedation during awake craniotomy for seizures: patient-controlled administration versus neurolept analgesia. Herrick IA, Craen RA, Gelb AW, Miller LA, Kubu CS, Girvin JP, Parrent AG, Eliasziw M, Kirkby J Intravenous anaesthetics: some cellular sites of action. Dzoljic M, Gelb AW Objective predictors of response for staple versus laser emphysematous lung reduction. Brenner M, McKenna R, Gelb A, Osann K, Schein MJ, Panzera J, Wong H, Berns MW, Wilson AF Propofol patient-controlled sedation during hip or knee arthroplasty in elderly patients. Ganapathy S, Herrick IA, Gelb AW, Kirkby J Anaesthetic management of a pregnant, post liver transplant patient for dental surgery. Avraamides EJ, Craen RA, Gelb AW Patient-controlled propofol sedation for elderly patients: safety and patient attitude toward control. Herrick IA, Gelb AW, Nichols B, Kirkby J Differences in peripheral arterial and venous hemorheologic parameters. Mokken FC, van der Waart FJ, Henny CP, Goedhart PT, Gelb AW Propofol induces dilation and inhibits constriction in guinea pig basilar arteries. Gelb AW, Zhang C, Hamilton JT Long-term survival and functional tolerance of baboon to monkey kidney and liver transplantation: a preliminary report. Zhong R, Tucker J, Grant D, Wall W, Garcia B, Asfar S, Zhang Z, Sharpe M, Gelb A, Stiller C The nervous system at risk--an overview. Gelb AW In vitro cerebral vasoactive effects of MK-801. Gelb AW, Zhang C, Hamilton JT Anesthesia for interventional neuroradiology. Manninen PH, Gignac EM, Gelb AW, Lownie SP Predicting perioperative stroke. Kim J, Gelb AW Propofol differentially attenuates the responses to exogenous and endogenous norepinephrine in the isolated rat femoral artery in vitro. Biddle NL, Gelb AW, Hamilton JT Actions of propofol on pontine neurons controlling arterial pressure in rats. Krassioukov AV, Gelb AW, Weaver LC Association between electrocardiographic abnormalities and intracranial blood in patients following acute subarachnoid hemorrhage. Manninen PH, Ayra B, Gelb AW, Pelz D Hemorrheological changes associated with brain death and their implications for potential organ donors. Mokken FC, Henny CP, Kedaria M, Gelb AW Cerebrovascular and cerebral metabolic effects of commonly used anaesthetics. Chong KY, Gelb AW Effects of nitrous oxide/oxygen-isoflurane anesthesia on blood cyclosporine concentrations in the rabbit. Freeman DJ, Sharpe MD, Gelb AW Evoked potential monitoring during posterior fossa aneurysm surgery: a comparison of two modalities. Manninen PH, Patterson S, Lam AM, Gelb AW, Nantau WE Action of propofol on central sympathetic mechanisms controlling blood pressure. Krassioukov AV, Gelb AW, Weaver LC Comparison of fentanyl, sufentanil and alfentanil during awake craniotomy for epilepsy. Gignac E, Manninen PH, Gelb AW The effects of propofol compared to high-dose fentanyl anesthesia on rheologic parameters in coronary artery surgery. Mokken FC, Henny CP, Gelb AW, Biervliet JD, Hardeman MR, Kedaria M, van Wezel HB Monitoring of brainstem function during vertebral basilar aneurysm surgery. The use of spontaneous ventilation. Manninen PH, Cuillerier DJ, Nantau WE, Gelb AW Cardiovascular effects of human insular cortex stimulation. Oppenheimer SM, Gelb A, Girvin JP, Hachinski VC Methylparaben and propylparaben do not alter cerebral blood flow in humans. Gelb AW, Gignac E, Manninen PH, Farrar JK, Lee DH The responsiveness of cerebral blood flow to changes in arterial carbon dioxide is maintained during propofol-nitrous oxide anesthesia in humans. Fox J, Gelb AW, Enns J, Murkin JM, Farrar JK, Manninen PH The anaesthetic management of neurosurgical emergencies. Craen RA, Gelb AW The anaesthetic management of neurosurgical emergencies. Craen RA, Gelb AW The clinical importance of erythrocyte deformability, a hemorrheological parameter. Mokken FC, Kedaria M, Henny CP, Hardeman MR, Gelb AW Anesthesia for intracranial aneurysm surgery. Herrick IA, Gelb AW Cardiac function in aneurysmal subarachnoid haemorrhage: a study of electrocardiographic and echocardiographic abnormalities. Davies KR, Gelb AW, Manninen PH, Boughner DR, Bisnaire D Isoflurane alters the kinetics of oral cyclosporine. Gelb AW, Freeman D, Robertson KM, Zhang C Effects of fentanyl, sufentanil, and alfentanil on brain retractor pressure. Herrick IA, Gelb AW, Manninen PH, Reichman H, Lownie S Brain retractor edema during induced hypotension: the effect of the rate of return of blood pressure. Lownie S, Wu X, Karlik S, Gelb AW Long-term cognitive and social sequelae of general versus regional anesthesia during arthroplasty in the elderly. Nielson WR, Gelb AW, Casey JE, Penny FJ, Merchant RN, Manninen PH Paraben preservatives but not succinylcholine are cerebral vasodilators in vitro. Hamilton JT, Zhou Y, Gelb AW Anaesthetic management of the brain dead for organ donation. Gelb AW, Robertson KM Cortical-evoked potentials and cerebral infarction in temporary middle cerebral artery occlusion in the cat. Shokunbi MT, Gelb AW A comparison of electrocardiographic and echocardiographic abnormalities in subarachnoid hemorrhage. Davies KR, Gelb A, Manninen PH, Boughner DR, Bisnaire D Cerebral oxygen consumption during sufentanil anesthesia: measurement by N2O uptake vs 133xenon clearance. Murkin JM, Farrar JK, McNeill B, Gelb AW, Lok P Monitoring of brain stem function during posterior fossa surgery. Manninen PH, Cuillerier DJ, Gelb AW, Nantau WE Preoperative anxiety: detection and contributing factors. Badner NH, Nielson WR, Munk S, Kwiatkowska C, Gelb AW Autoregulation and the CO2 responsiveness of cerebral blood flow after cardiopulmonary bypass. McNeill BR, Murkin JM, Farrar JK, Gelb AW Changes in the somatosensory evoked potential during and immediately following temporary middle cerebral artery occlusion predict somatosensory cortex ischemic lesions in monkeys. Dowman R, Boisvert DP, Gelb AW, Tang C, Lam AM, Meilke B Perioperative monitoring of the electrocardiogram during cerebral aneurysm surgery. Manninen PH, Gelb AW, Lam AM, Moote CA, Contreras J Systemic hypovolemia after subarachnoid hemorrhage. Brazenor GA, Chamberlain MJ, Gelb AW Preoperative hypertension does predict post-carotid endarterectomy hypertension. Gelb AW, Herrick IA Succinylcholine does not increase serum potassium levels in patients with acutely ruptured cerebral aneurysms. Manninen PH, Mahendran B, Gelb AW, Merchant RN Continuous lidocaine infusion and focal feline cerebral ischemia. Shokunbi MT, Gelb AW, Wu XM, Miller DJ Local anesthetics in cerebral ischemia. Gelb AW Isoflurane for refractory status epilepticus: a clinical series. Kofke WA, Young RS, Davis P, Woelfel SK, Gray L, Johnson D, Gelb A, Meeke R, Warner DS, Pearson KS Isoflurane for the management of status epilepticus. Meeke RI, Soifer BE, Gelb AW The influence of cardiopulmonary bypass on cerebral autoregulation and CO2 responsiveness in the early postoperative period. McNeill BR, Murkin JM, Farrar JK, Gelb AW The multiple organ donor: identification and management. Soifer B, Gelb AW Primate brain tolerance to temporary focal cerebral ischemia during isoflurane- or sodium nitroprusside-induced hypotension. Gelb AW, Boisvert DP, Tang C, Lam AM, Marchak BE, Dowman R, Mielke BW Endocrine changes and haemodynamic stability after brain death. Robertson KM, Hramiak IM, Gelb AW Brain tolerance to middle cerebral artery occlusion during hypotension in primates. Boisvert DP, Gelb AW, Tang C, Lam AM, Mielke B, Dowman R HIV infection control issues concerning first responders and emergency physicians. Gelb A The effects of a prophylactic bolus of lidocaine in focal cerebral ischaemia. Gelb AW, Steinberg GK, Lam AM, Manninen PH, Peerless SJ, Rassi-Neto A Patient anesthesia and monitoring at a 1.5-T MRI installation. Karlik SJ, Heatherley T, Pavan F, Stein J, Lebron F, Rutt B, Carey L, Wexler R, Gelb A The stress response to induced hypotension for cerebral aneurysm surgery: a comparison of two hypotensive techniques. Macnab MS, Manninen PH, Lam AM, Gelb AW Electrocardiographic changes during and after isoflurane-induced hypotension for neurovascular surgery. Manninen PH, Lam AM, Gelb AW The effect of high-dose mannitol on serum and urine electrolytes and osmolality in neurosurgical patients. Manninen PH, Lam AM, Gelb AW, Brown SC Anaesthesia for organ transplantation. Gelb AW Ethical and family management problems in the intensive care unit--an illustrative case. Burden JM, Freedman B, Gelb AW Ethical and family management problems in the intensive care unit--an illustrative case. Burden JM, Freedman B, Gelb AW Etomidate reversibly depresses human neutrophil chemiluminescence. Gelb AW, Lok P Correlation between somatosensory evoked potentials and neuronal ischemic changes following middle cerebral artery occlusion. Steinberg GK, Gelb AW, Lam AM, Manninen PH, Peerless SJ, Rassi Neto A, Floyd P An evaluation of the effect of lidocaine in experimental focal cerebral ischemia. Shokunbi MT, Gelb AW, Peerless SJ, Mervart M, Floyd P Controversies in cardiopulmonary resuscitation. Wexler HR, Gelb AW A prophylactic bolus of thiopentone does not protect against prolonged focal cerebral ischaemia. Gelb AW, Floyd P, Lok P, Peerless SJ, Farrell M The effect of isoflurane-induced hypotension on cerebral blood flow and cerebral metabolic rate for oxygen in humans. Newman B, Gelb AW, Lam AM Anesthetics change tissue proton NMR relaxation. Karlik SJ, Fuller J, Gelb AW Enflurane and halothane in status asthmaticus. Echeverria M, Gelb AW, Wexler HR, Ahmad D, Kenefick P Homeostatic alterations with major trauma. Pulmonary dysfunction in trauma. Gelb AW Air embolism during liver transplantation. Kutt JL, Gelb AW Benzodiazepines and polymorphonuclear leukocyte oxidative activity. Gelb A An unusual case of malignant melanoma of the small intestine. Raymond AR, Rorat E, Goldstein D, Lubat E, Strutynsky N, Gelb A Succinylcholine and intracranial pressure--a cause for "pause". Lam AM, Gelb AW Anesthetic considerations for carotid endarterectomy. Gelb AW The anaesthetist and the head-injured patient. Gelb AW, Manninen PH, Mezon BJ, Lee RJ, Durward QJ Sedation and respiratory mechanics in man. Gelb A, Southorn P, Rehder K, Didier EP The effects of intravenous anaesthetic agents on human neutrophil chemiluminescence. White IW, Gelb AW, Wexler HR, Stiller CR, Keown PA Cardiovascular effects of isoflurane-induced hypotension for cerebral aneurysm surgery. Lam AM, Gelb AW Peripheral chemoreceptors during anesthesia: are the watchdogs sleeping? Knill RL, Gelb AW Pseudohypotension. Gelb AW, Lam AM Effect of general anaesthesia on respiratory function. Gelb AW, Southorn P, Rehder K Subanaesthetic halothane: its effect on regulation of ventilation and relevance to the recovery room. Gelb AW, Knill RL Ventilatory responses to hypoxia and hypercapnia during halothane sedation and anesthesia in man. Knill RL, Gelb AW Ventilatory responses mediated by peripheral chemoreceptors in anaesthetized man. Knill RL, Clement JL, Gelb AW Achalasia with suppurative pericarditis. A case report. French T, Kench P, Swanepoel A, Hewitson R, Gelb A