Role Staff Location Zuckerberg San Francisco General Hospital Category Research Education Ph.D., 06/1989 - Biochemistry, Tufts UniversityBSc(Hons), 6/1980 - Chemistry, University of Southampton Publications Single Tri-Epitopic Antibodies (TeAbs) to Botulinum Neurotoxin Serotypes B, E, and F Recapitulate the Full Potency of a Combination of Three Monoclonal Antibodies in Toxin Neutralization. Lou J, Wen WH, Conrad F, Tam CC, Garcia-Rodriguez C, Farr-Jones S, Marks JD Toxins . Jun 4, 2025 Disinfection of needleless connectors for catheters in one second using a hand-held UV device. Fourkas M, Takami E, Schears GJ, Farr-Jones S, Rasooly J American journal of infection control . Apr 22, 2024 A Three-Monoclonal Antibody Combination Potently Neutralizes BoNT/G Toxin in Mice. Fan Y, Lou J, Tam CC, Wen W, Conrad F, Leal da Silva Alves P, Cheng LW, Garcia-Rodriguez C, Farr-Jones S, Marks JD Toxins . Apr 30, 2023 Multicolor fluorescence activated cell sorting to generate humanized monoclonal antibody binding seven subtypes of BoNT/F. Fan Y, Sun Z, Conrad F, Wen W, Zhao L, Lou J, Zhou Y, Farr-Jones S, Marks JD PloS one . Sep 1, 2022 Neutralizing Concentrations of Anti-Botulinum Toxin Antibodies Positively Correlate with Mouse Neutralization Assay Results in a Guinea Pig Model. Tomic MT, Farr-Jones S, Syar ES, Niemuth N, Kobs D, Hackett MJ, Espinoza Y, Martinez Z, Pham K, Snow DM, Marks JD, Cobb RR Toxins . Sep 21, 2021 A Four-Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotypes C and D. Garcia-Rodriguez C, Yan S, Geren IN, Knopp KA, Dong J, Sun Z, Lou J, Conrad F, Wen WH, Farr-Jones S, Smith TJ, Brown JL, Skerry JC, Smith LA, Marks JD Toxins . Sep 10, 2021 Identification of recombinant Fabs for structural and functional characterization of HIV-host factor complexes. Sevillano N, Green EM, Votteler J, Kim DY, Ren X, Yang B, Liu X, Lourenço AL, Hurley JH, Farr-Jones S, Gross JD, Cheng Y, Craik CS PloS one . May 13, 2021 A Monoclonal Antibody Combination against both Serotypes A and B Botulinum Toxin Prevents Inhalational Botulism in a Guinea Pig Model. Snow DM, Cobb RR, Martinez J, Finger-Baker I, Collins L, Terpening S, Syar ES, Niemuth N, Kobs D, Barnewall R, Farr-Jones S, Marks JD, Tomic MT Toxins . Jan 5, 2021 Antibody-Drug Conjugates Targeting the Urokinase Receptor (uPAR) as a Possible Treatment of Aggressive Breast Cancer. Harel ET, Drake PM, Barfield RM, Lui I, Farr-Jones S, Van't Veer L, Gartner ZJ, Green EM, Lourenço AL, Cheng Y, Hann BC, Rabuka D, Craik CS Antibodies (Basel, Switzerland) . Nov 5, 2019 Pharmacokinetics of Human Recombinant Anti-Botulinum Toxin Antibodies in Rats. Espinoza Y, Wong D, Ahene A, Der K, Martinez Z, Pham J, Cobb RR, Farr-Jones S, Marks JD, Tomic MT Toxins . Jun 17, 2019 Monoclonal Antibody Combinations Prevent Serotype A and Serotype B Inhalational Botulism in a Guinea Pig Model. Tomic MT, Espinoza Y, Martinez Z, Pham K, Cobb RR, Snow DM, Earnhart CG, Pals T, Syar ES, Niemuth N, Kobs DJ, Farr-Jones S, Marks JD Toxins . Apr 6, 2019 An ambient temperature-stable antitoxin of nine co-formulated antibodies for botulism caused by serotypes A, B and E. Li M, Lee D, Obi CR, Freeberg JK, Farr-Jones S, Tomic MT PloS one . May 10, 2018 Antibody engineering to improve manufacturability. Wijesuriya SD, Pongo E, Tomic M, Zhang F, Garcia-Rodriquez C, Conrad F, Farr-Jones S, Marks JD, Horwitz AH Protein expression and purification . Apr 12, 2018 A Three Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotype E Subtypes. Garcia-Rodriguez C, Razai A, Geren IN, Lou J, Conrad F, Wen WH, Farr-Jones S, Smith TJ, Brown JL, Skerry JC, Smith LA, Marks JD Toxins . Mar 1, 2018 A Single Tri-Epitopic Antibody Virtually Recapitulates the Potency of a Combination of Three Monoclonal Antibodies in Neutralization of Botulinum Neurotoxin Serotype A. Lou J, Wen W, Conrad F, Meng Q, Dong J, Sun Z, Garcia-Rodriguez C, Farr-Jones S, Cheng LW, Henderson TD, Brown JL, Smith TJ, Smith LA, Cormier A, Marks JD Toxins . Feb 15, 2018 Discovery of internalizing antibodies to basal breast cancer cells. Zhou Y, Zou H, Yau C, Zhao L, Hall SC, Drummond DC, Farr-Jones S, Park JW, Benz CC, Marks JD Protein engineering, design & selection : PEDS . Jan 1, 2018 High-throughput screening: update on practices and success. Fox S, Farr-Jones S, Sopchak L, Boggs A, Nicely HW, Khoury R, Biros M Journal of biomolecular screening . Sep 14, 2006 High-throughput screening: searching for higher productivity. Fox S, Farr-Jones S, Sopchak L, Boggs A, Comley J Journal of biomolecular screening . Jun 1, 2004 High throughput screening 2002: moving toward increased success rates. Fox S, Wang H, Sopchak L, Farr-Jones S Journal of biomolecular screening . Aug 1, 2002 Business and science of proteomics--third annual event. Next-generation technologies for high-throughput proteomics. Farr-Jones S IDrugs : the investigational drugs journal . Nov 1, 2001 The Internet for nuclear magnetic resonance spectroscopists. Avizonis D, Farr-Jones S Methods in enzymology . Jan 1, 2001 Chemokine antagonists as anti-inflammatory and antiviral agents II. Farr-Jones S IDrugs : the investigational drugs journal . Jun 1, 2000 Solution structure of Syrian hamster prion protein rPrP(90-231). Liu H, Farr-Jones S, Ulyanov NB, Llinas M, Marqusee S, Groth D, Cohen FE, Prusiner SB, James TL Biochemistry . Apr 27, 1999 High Throughput Screening for Drug Discovery: Continually Transitioning into New Technology. Fox S, Farr-Jones S, Yund MA Journal of biomolecular screening . Jan 1, 1999 NMR determination of the major solution conformation of a peptoid pentamer with chiral side chains. Armand P, Kirshenbaum K, Goldsmith RA, Farr-Jones S, Barron AE, Truong KT, Dill KA, Mierke DF, Cohen FE, Zuckermann RN, Bradley EK Proceedings of the National Academy of Sciences of the United States of America . Apr 14, 1998 Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform. James TL, Liu H, Ulyanov NB, Farr-Jones S, Zhang H, Donne DG, Kaneko K, Groth D, Mehlhorn I, Prusiner SB, Cohen FE Proceedings of the National Academy of Sciences of the United States of America . Sep 16, 1997 Solution structure of omega-conotoxin MVIIC, a high affinity ligand of P-type calcium channels, using 1H NMR spectroscopy and complete relaxation matrix analysis. Farr-Jones S, Miljanich GP, Nadasdi L, Ramachandran J, Basus VJ Journal of molecular biology . Apr 21, 1995 Converting trypsin to chymotrypsin: ground-state binding does not determine substrate specificity. Hedstrom L, Farr-Jones S, Kettner CA, Rutter WJ Biochemistry . Jul 26, 1994 Crystal versus solution structure of enzymes: NMR spectroscopy of a peptide boronic acid-serine protease complex in the crystalline state. Farr-Jones S, Smith SO, Kettner CA, Griffin RG, Bachovchin WW Proceedings of the National Academy of Sciences of the United States of America . Sep 1, 1989 Crystal versus solution structures of enzymes: NMR spectroscopy of a crystalline serine protease. Smith SO, Farr-Jones S, Griffin RG, Bachovchin WW Science (New York, N.Y.) . May 26, 1989 Nitrogen-15 NMR spectroscopy of the catalytic-triad histidine of a serine protease in peptide boronic acid inhibitor complexes. Bachovchin WW, Wong WY, Farr-Jones S, Shenvi AB, Kettner CA Biochemistry . Oct 4, 1988
