Biography Dr. Prasad Shirvalkar is a neurologist and interventional pain medicine specialist who provides the full spectrum of care for chronic pain conditions. This includes conservative, nonsurgical treatments such as medications and nerve blocks. He also treats patients with advanced neuromodulation therapy by implanting peripheral and spinal cord stimulators, which are devices that relieve pain by sending electrical signals to the spine. Shirvalkar cares for hospitalized patients and provides telemedicine visits for established patients. He coordinates with other providers for each patient, collaborating to treat any pain condition. Shirvalkar's research aims to develop new therapies for hard-to-treat pain disorders, such as post-stroke pain and phantom limb pain, by harnessing technologies such as brain and spinal cord stimulation. He is conducting a study using electrodes implanted in the brain to understand how individuals interpret pain signals, with the goal of personalizing brain stimulation therapies. He is also interested in how sudden, severe pain episodes can progress to become chronic and in whether early intervention can prevent chronic pain. Shirvalkar earned his doctoral and medical degrees at Icahn School of Medicine at Mount Sinai. He then completed a residency in neurology at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center, where he served as chief resident. He completed a fellowship in pain management at UCSF. In addition to medicine and science, Shirvalkar has a passion for percussion. He plays jazz drums in his free time and used to play with the Oakland Raiders' band. Role Faculty Location UCSF at Mission Bay Category Clinical Research Specialties Pain Medicine Education Fellowship, 2017 - Pain Management, University of California San FranciscoResidency, 2016 - Neurology, Weill Cornell Medical College / Memorial Sloan Kettering Cancer CenterMD PhD, 2012 - PhD - Neuroscience, Icahn School of Medicine at Mount SinaiPostdoctoral, 2012 - Neuroscience, Rockefeller University Publications ID# 1904948 Rational and Plan of Analysis of the Neuromodulation Overcomes Restless Legs Syndrome (NO RLS) Study. Marshall T. Holland, Prasad Shirvalkar, Zachary Irwin, Chris Gonzalez, Christopher Earley, Julie Pilitsis, Robert Oster, Harrison Walker ID# 1907226 A Randomized Clinical Trial of Primary Motor Cortex Transcranial Magnetic Stimulation for Trigeminal Neuropathic Pain. Julian C. Motzkin, Dennis Lambert, Tenzin Norbu, A. Moses Lee, Andrew Krystal, Prasad Shirvalkar Towards individualized deep brain stimulation: A stereoencephalography-based workflow for unbiased neurostimulation target identification. Saal J, Kadlec K, Allawala AB, Johnston L, Leriche RB, Vatsyayan R, Han Y, Kist A, Di Ianni T, Dawes HE, Chang EF, Lee AM, Krystal AD, Moussawi K, Shirvalkar P, Sellers KK Adaptive spinal cord stimulation improves restless legs syndrome: Case report, literature review, and mechanistic hypothesis. Holland MT, Mekhail MN, Thrash G, George T, Mugan D, Paul C, Shirvalkar P, Grace W, Deer T, McGregor K, Vazquez do Campo R, Earley CJ, Walker HC Brain Biomarkers for Pain Sensitivity. Shirvalkar P, Rozell CJ Closed-loop deep brain stimulation for chronic pain using personalized symptom biomarkers. Prasad Shirvalkar, Ryan Leriche, Jeremy Saal, Philip Starr, Edward Chang Personalized brain network dynamics of spontaneous and evoked pain - influence of responsive brain stimulation. Prasad Shirvalkar, Ryan Leriche, Jeremy Saal, Philip Starr, Edward Chang Revisiting brain stimulation for chronic pain: New approaches based on pathophysiology. Zelma Kiss, Ausaf Bari, Giulia Liberati, Prasad Shirvalkar Uncovering the dynamics of psilocybin in human neural pain circuits with intracranial neural recordings. Tess Veuthey, Prasad Shirvalkar Clinical trials in neuromodulatory treatment of drug-resistant hypertension and the need for spinal cord stimulation trials: a PRISMA systematic review. Thrash GW, Wang E, Sun Y, Walker HC, Shirvalkar P, Becker BK, Holland MT Neuropathic pain - A clinical primer. Shirvalkar P, de Andrade DC ID: 334564 EEG Signatures of Epidural Spinal Cord Stimulation: A Dosing and Mechanism of Action Study. Chad Sitgraves, Prasad Shirvalkar, Lawrence Poree ID: 334648 Brain Mapping with Stereoelectroencephalography Reveals Altered Network Topologies in Chronic Pain. Ishan Kanungo, Tony Liu, Julian Motzkin, Prasad Shirvalkar Neuromodulation for Neuropathic Pain Syndromes. Shirvalkar P Human Cervical Epidural Spinal Electrogram Topographically Maps Distinct Volitional Movements. Shukla PD, Burke JF, Kunwar N, Presbrey K, Balakid J, Yaroshinsky M, Louie K, Jacques L, Shirvalkar P, Wang DD Ambulatory Brain Biomarkers of Chronic Pain: Towards Closed Loop Brain Stimulation. Prasad Shirvalkar, Philip A. Starr, Edward F. Chang Editorial: Advancements in deep brain stimulation for chronic pain control. Staudt MD, Yaghi NK, Mazur-Hart DJ, Shirvalkar P Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams. Kwong J, Lin J, Leriche R, Wozny TA, Shaughnessy A, Schmitgen A, Shirvalkar P Network targets for therapeutic brain stimulation: towards personalized therapy for pain. Motzkin JC, Kanungo I, D'Esposito M, Shirvalkar P ID: 221565 EEG Signatures of Epidural Spinal Cord Stimulation: A Dosing and Mechanism of Action Study. Chad Sitgraves, Prasad Shirvalkar, Lawrence Poree First-in-human prediction of chronic pain state using intracranial neural biomarkers. Shirvalkar P, Prosky J, Chin G, Ahmadipour P, Sani OG, Desai M, Schmitgen A, Dawes H, Shanechi MM, Starr PA, Chang EF How SAFE Is Real-world Use of Spinal Cord Stimulation Therapy for Chronic Pain? Shirvalkar P, Poree L Proceedings of the Ninth Annual Deep Brain Stimulation Think Tank: Advances in Cutting Edge Technologies, Artificial Intelligence, Neuromodulation, Neuroethics, Pain, Interventional Psychiatry, Epilepsy, and Traumatic Brain Injury. Wong JK, Deuschl G, Wolke R, Bergman H, Muthuraman M, Groppa S, Sheth SA, Bronte-Stewart HM, Wilkins KB, Petrucci MN, Lambert E, Kehnemouyi Y, Starr PA, Little S, Anso J, Gilron R, Poree L, Kalamangalam GP, Worrell GA, Miller KJ, Schiff ND, Butson CR, Henderson JM, Judy JW, Ramirez-Zamora A, Foote KD, Silburn PA, Li L, Oyama G, Kamo H, Sekimoto S, Hattori N, Giordano JJ, DiEuliis D, Shook JR, Doughtery DD, Widge AS, Mayberg HS, Cha J, Choi K, Heisig S, Obatusin M, Opri E, Kaufman SB, Shirvalkar P, Rozell CJ, Alagapan S, Raike RS, Bokil H, Green D, Okun MS Practical Closed-Loop Strategies for Deep Brain Stimulation: Lessons From Chronic Pain. Prosky J, Cagle J, Sellers KK, Gilron R, de Hemptinne C, Schmitgen A, Starr PA, Chang EF, Shirvalkar P Epidural Spinal Electrogram Provides Direct Spinal Recordings in Awake Human Participants. Burke JF, Kunwar N, Yaroshinsky MS, Louie KH, Shirvalkar P, Su P, Henry M, Pasvankas G, Poree L, Jacques L, Wang DD Corrigendum: Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies. Vedam-Mai V, Deisseroth K, Giordano J, Lazaro-Munoz G, Chiong W, Suthana N, Langevin JP, Gill J, Goodman W, Provenza NR, Halpern CH, Shivacharan RS, Cunningham TN, Sheth SA, Pouratian N, Scangos KW, Mayberg HS, Horn A, Johnson KA, Butson CR, Gilron R, de Hemptinne C, Wilt R, Yaroshinsky M, Little S, Starr P, Worrell G, Shirvalkar P, Chang E, Volkmann J, Muthuraman M, Groppa S, Kühn AA, Li L, Johnson M, Otto KJ, Raike R, Goetz S, Wu C, Silburn P, Cheeran B, Pathak YJ, Malekmohammadi M, Gunduz A, Wong JK, Cernera S, Hu W, Wagle Shukla A, Ramirez-Zamora A, Deeb W, Patterson A, Foote KD, Okun MS High-Frequency Impulse Therapy for Treatment of Chronic Back Pain: A Multicenter Randomized Controlled Pilot Study. Amirdelfan K, Hong M, Tay B, Reddy S, Reddy V, Yang M, Khanna K, Shirvalkar P, Abrecht C, Gulati A Analysis-rcs-data: Open-Source Toolbox for the Ingestion, Time-Alignment, and Visualization of Sense and Stimulation Data From the Medtronic Summit RC+S System. Sellers KK, Gilron R, Anso J, Louie KH, Shirvalkar PR, Chang EF, Little SJ, Starr PA Emerging Therapies for the Treatment of Complex Regional Pain Syndrome. Po-Yi Paul Su, Shikha Sharma, Prasad Shirvalkar, Lawrence Poree Musical Hallucinations in Chronic Pain: The Anterior Cingulate Cortex Regulates Internally Generated Percepts. Schmitgen A, Saal J, Sankaran N, Desai M, Joseph I, Starr P, Chang EF, Shirvalkar P Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies. Vedam-Mai V, Deisseroth K, Giordano J, Lazaro-Munoz G, Chiong W, Suthana N, Langevin JP, Gill J, Goodman W, Provenza NR, Halpern CH, Shivacharan RS, Cunningham TN, Sheth SA, Pouratian N, Scangos KW, Mayberg HS, Horn A, Johnson KA, Butson CR, Gilron R, de Hemptinne C, Wilt R, Yaroshinsky M, Little S, Starr P, Worrell G, Shirvalkar P, Chang E, Volkmann J, Muthuraman M, Groppa S, Kühn AA, Li L, Johnson M, Otto KJ, Raike R, Goetz S, Wu C, Silburn P, Cheeran B, Pathak YJ, Malekmohammadi M, Gunduz A, Wong JK, Cernera S, Hu W, Wagle Shukla A, Ramirez-Zamora A, Deeb W, Patterson A, Foote KD, Okun MS The American Society of Pain and Neuroscience (ASPN) Practical Guidelines to Study Design and Scientific Manuscript Preparation in Neuromodulation. Eshraghi Y, Chakravarthy K, Strand NH, Shirvalkar P, Schuster NM, Abdallah RT, Vallejo R, Sayed D, Kim D, Kim C, Meacham K, Deer T, Translational Research Committee American Society of Pain and Neuroscience (ASPN) A Tale of Two Cords: Diastematomyelia. Westin Tom, Thoha Pham, Prasad Shirvalkar A Deep Brain Stimulation Trial Period for Treating Chronic Pain. Shirvalkar P, Sellers KK, Schmitgen A, Prosky J, Joseph I, Starr PA, Chang EF A Comprehensive Practice Guideline for Magnetic Resonance Imaging Compatibility in Implanted Neuromodulation Devices. Sayed D, Chakravarthy K, Amirdelfan K, Kalia H, Meacham K, Shirvalkar P, Falowski S, Petersen E, Hagedorn JM, Pope J, Leever J, ASPN MRI Compatibility Working Group, Deer T Cognitive Effects of Limbic Deep Brain Stimulation in Patients with Refractory Chronic Neuropathic Pain (1990). Gregory Chin, Heather Dawes, Edward Chang, Prasad Shirvalkar Decoding Acute and Chronic Pain State from Ambulatory Intracranial Recordings: Towards Closed-Loop Brain Stimulation (233). Prasad Shirvalkar, Gregory Chin, Heather Dawes, Philip Starr, Edward Chang Transcranial Magnetic Stimulation for Pain, Headache, and Comorbid Depression: INS-NANS Expert Consensus Panel Review and Recommendation. Leung A, Shirvalkar P, Chen R, Kuluva J, Vaninetti M, Bermudes R, Poree L, Wassermann EM, Kopell B, Levy R, and the Expert Consensus Panel Large expert-curated database for benchmarking document similarity detection in biomedical literature search. eter Brown, Aik-Choon Tan, Mohamed A El-Esawi, Thomas Liehr, Oliver Blanck, Douglas P Gladue, Gabriel M F Almeida, Tomislav Cernava, Carlos O Sorzano, Andy W K Yeung, Michael S Engel, Arun Richard Chandrasekaran, Thilo Muth, Martin S Staege, Swapna V Daulatabad, Darius Widera, Junpeng Zhang, Adrian Meule, Ken Honjo, Olivier Pourret, Cong-Cong Yin, Zhongheng Zhang, Marco Cascella, Willy A Flegel, Carl S Goodyear, Mark J van Raaij, Zuzanna Bukowy-Bieryllo, Luca G Campana, Nicholas A Kurniawan, David Lalaouna, Felix J Hüttner, Brooke A Ammerman, Felix Ehret, Paul A Cobine, Ene-Choo Tan, Hyemin Han, Wenfeng Xia, Christopher McCrum, Ruud P M Dings, Francesco Marinello, Henrik Nilsson, Brett Nixon, Konstantinos Voskarides, Long Yang, Vincent D Costa, Johan Bengtsson-Palme, William Bradshaw, Dominik G Grimm, Nitin Kumar, Elvis Martis, Daniel Prieto, Sandeep C Sabnis, Said E D R Amer, Alan W C Liew, Paul Perco, Farid Rahimi, Giuseppe Riva, Chongxing Zhang, Hari P Devkota, Koichi Ogami, Zarrin Basharat, Walter Fierz, Robert Siebers, Kok-Hian Tan, Karen A Boehme, Peter Brenneisen, James A L Brown, Brian P Dalrymple, David J Harvey, Grace Ng, Sebastiaan Werten, Mark Bleackley, Zhanwu Dai, Raman Dhariwal, Yael Gelfer, Marcus D Hartmann, Pawel Miotla, Radu Tamaian, Pragashnie Govender, Oliver J Gurney-Champion, Joonas H Kauppila, Xiaolei Zhang, Natalia Echeverría, Santhilal Subhash, Hannes Sallmon, Marco Tofani, Taeok Bae, Oliver Bosch, Páraic O Cuív, Antoine Danchin, Barthelemy Diouf, Tuomas Eerola, Evangelos Evangelou, Fabian V Filipp, Hannes Klump, Lukasz Kurgan, Simon S Smith, Olivier Terrier, Neil Tuttle, David B Ascher, Sarath C Janga, Leon N Schulte, Daniel Becker, Christopher Browngardt, Stephen J Bush, Guillaume Gaullier, Kazuki Ide, Clement Meseko, Gijsbert D A Werner, Jan Zaucha, Abd A Al-Farha, Noah F Greenwald, Segun I Popoola, Shaifur Rahman, Jialin Xu, Sunny Y Yang, Noboru Hiroi, Ozgul M Alper, Chris I Baker, Michael Bitzer, George Chacko, Birgit Debrabant, Ray Dixon, Evelyne Forano, Matthew Gilliham, Sarah Kelly, Karl-Heinz Klempnauer, Brett A Lidbury, Michael Z Lin, Iseult Lynch, Wujun Ma, Edward W Maibach, Diane E Mather, Kutty S Nandakumar, Robert S Ohgami, Piero Parchi, Patrizio Tressoldi, Yu Xue, Charles Armitage, Pierre Barraud, Stella Chatzitheochari, Luis P Coelho, Jiajie Diao, Andrew C Doxey, Angélique Gobet, Pingzhao Hu, Stefan Kaiser, Kate M Mitchell, Mohamed F Salama, Ivan G Shabalin, Haijun Song, Dejan Stevanovic, Ali Yadollahpour, Erliang Zeng, Katharina Zinke, C G Alimba, Tariku J Beyene, Zehong Cao, Sherwin S Chan, Michael Gatchell, Andreas Kleppe, Marcin Piotrowski, Gonzalo Torga, Adugna A Woldesemayat, Mehmet I Cosacak, Scott Haston, Stephanie A Ross, Richard Williams, Alvin Wong, Matthew K Abramowitz, Andem Effiong, Senhong Lee, Muhammad Bilal Abid, Cyrus Agarabi, Cedric Alaux, Dirk R Albrecht, Gerald J Atkins, Charles R Beck, A M J J Bonvin, Emer Bourke, Thomas Brand, Ralf J Braun, James A Bull, Pedro Cardoso, Dee Carter, Robin M Delahay, Bernard Ducommun, Pascal H G Duijf, Trevor Epp, Eeva-Liisa Eskelinen, Mazyar Fallah, Debora B Farber, Jose Fernandez-Triana, Frank Feyerabend, Tullio Florio, Michael Friebe, Saori Furuta, Mads Gabrielsen, Jens Gruber, Malgorzata Grybos, Qian Han, Michael Heinrich, Heikki Helanterä, Michael Huber, Albert Jeltsch, Fan Jiang, Claire Josse, Giuseppe Jurman, Haruyuki Kamiya, Kim de Keersmaecker, Erik Kristiansson, Frank-Erik de Leeuw, Jiuyong Li, Shide Liang, Jose A Lopez-Escamez, Francisco J Lopez-Ruiz, Kevin J Marchbank, Rolf Marschalek, Carmen S Martín, Adriana E Miele, Xavier Montagutelli, Esteban Morcillo, Rosario Nicoletti, Monika Niehof, Ronan O’Toole, Toshihiko Ohtomo, Henrik Oster, Jose-Alberto Palma, Russell Paterson, Mark Peifer, Maribel Portilla, M C Portillo, Antonia L Pritchard, Stefan Pusch, Gajendra P S Raghava, Nicola J Roberts, Kehinde Ross, Birgitt Schuele, ... Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain. Shirvalkar P, Veuthey TL, Dawes HE, Chang EF Chapter 47 The Development of Algorithms for Pain Care Including Neuromodulation Therapies Introducing the SAFE Principles. Prasad Shirvalkar, Lawrence R. Poree, Elliot S. Krames List of Contributors of Volume 2. Al-Kaisy Adnan, Andreas Alexopoulos, Kenneth M. Alo, Ron L. Alterman, Arun Amar, Pablo Andrade, Sailesh Arulkumar, Ahmed J. Awad, Gordon Baltuch, Giancarlo Barolat, Ernest J. Barthélemy, Neil U. Barua, Maria E. Bennett, Nicole Bentley, Yarema B. Bezchlibnyk, Kelly R. Bijanki, William Bingaman, Joseph W. Boggs, Paul Boon, Brigitte A. Brouwer, Lucas W. Campos, Anthony Caparso, Annamaria Capozzo, John Chae, Jin Woo Chang, Jennifer Cheng, David Copenhaver, Timothy R. Deer, Milind Deogaonkar, Deepali Dhar, Keeley Dohmeier, Darin D. Dougherty, Dominique M. Durand, Kelly Foote, Jeffrey Gilligan, Steven S. Gill, Jorge Gonzalez-Martinez, Benjamin D. Greenberg, Robert E. Gross, Michael H. Pourfar, Clement Hamani, Salim M. Hayek, Paul E. Holtzheimer, Brian M. Ilfeld, Haiyan Jin, Bert Joosten, Na Young Jung, Chong H. Kim, Young Goo Kim, Martin Klehr, Paul Koch, Sina Kohl, Brian H. Kopell, Daniel Kramer, Elliot S. Krames, Balu Krishnan, Vibhor Krishna, Jens Kuhn, Jason Kyung-soo Hong, Kapural Leonardo, Michael S. Leong, Dianyou Li, Andreas A. Linninger, Nir Lipsman, Charles Liu, Andres M. Lozano, Michael Mackow, Mark N. Malinowski, Helen S. Mayberg, Paolo Mazzone, Ankit I. Mehta, Vivek Mehta, Reversa Mills-Joseph, Dileep Nair, Richard B. North, Michael Okun, Nikunj K. Patel, Parag G. Patil, Jason E. Pope, Lawrence R. Poree, Joshua P. Prager, Robrecht Raedt, Jonathan J. Rasouli, Serge Rasskazoff, Richard Rauck, Kevin Reeves, Ali R. Rezai, Jonathan Russin, Abraham Sabersky, Michael Saulino, Eugenio Scarnati, Stefan Schu, Mayur Sharma, Jane Shipley, Prasad Shirvalkar, Konstantin V. Slavin, Michael Stanton-Hicks, Scellig Stone, William A. Stuart, Bomin Sun, Kevin Tangen, Stewart J. Tepper, Maarten van Kleef, Tim Vancamp, Paul Verrills, Fabio Viselli, Veerle Visser-Vandewalle, Flora Vitale, Kristl Vonck, Tao Wang, Xuelian Wang, Richard L. Weiner, Alik S. Widge, Amorn Wongsarnpigoon, Alon Y. Mogilner, Kurt A. Yaeger, Tony L. Yaksh, Dali Yin, Kristina Zeljic, Chencheng Zhang, Shikun Zhan Improving lower limb strength in incomplete spinal cord injury with non-invasive spinal associative stimulation. M. Cortes, G. Thickbroom, J. Valls-Sole, P. Shirvalkar, A. Pascual-Leone, D. Edwards Amyloid-Beta Related Angitiis and Reversible Cerebral Vasoconstriction Syndrome: A Case Report (P6.057). Thomas Tropea, Prasad Shirvalkar, Krithiga Sekar, Kyung-Wha Kim, Apostolos Tsiouris, Ehud Lavi, Alan Segal Conference Curriculum Content and Organization in United States Neurology Residencies: A Cross-Sectional Survey (P2.354). Arthie Jeyakumar, Pravin Khemani, Ralph Jozefowicz, Prasad Shirvalkar, Augusto Miravalle, Constantine Farmakidis American neuroborreliosis presenting as cranial polyneuritis and radiculoneuritis. Wang E, Shirvalkar PR, Maciel CB, Merkler AE, Safdieh J, Gupta A Widespread Leptomeningeal Involvement in Borreliosis (P2.317). Carolina Maciel, Erwin Wang, Prasad Shirvalkar, Alexander Merkler, Joseph Safdieh Memory-guided learning: CA1 and CA3 neuronal ensembles differentially encode the commonalities and differences between situations. Bahar AS, Shirvalkar PR, Shapiro ML Memory modulates journey-dependent coding in the rat hippocampus. Ferbinteanu J, Shirvalkar P, Shapiro ML Design and Construction of a Cost Effective Headstage for Simultaneous Neural Stimulation and Recording in the Water Maze. Prasad R. Shirvalkar, Mathew L. Shapiro Design and construction of a cost effective headstage for simultaneous neural stimulation and recording in the water maze. Shirvalkar PR, Shapiro ML Infrageniculate Interventions in Female Patients: Improved Patency Rates but Higher Rates of Postoperative Complications. Tejas R. Shah, Angeliki Vouyouka, Daniel K. Han, Sharif Ellozy, Robert Lookstein, Prasad Shirvalkar, Michael Marin, Peter L. Faries Bidirectional changes to hippocampal theta-gamma comodulation predict memory for recent spatial episodes. Shirvalkar PR, Rapp PR, Shapiro ML The multiple origins and laminar topography of the hippocampal theta rhythm. Shirvalkar P, Bahar AS Hippocampal neural assemblies and conscious remembering. Shirvalkar PR Cognitive enhancement with central thalamic electrical stimulation. Shirvalkar P, Seth M, Schiff ND, Herrera DG Regulation of neurogenesis in the aging vertebrate brain: role of oxidative stress and neuropsychiatric factors. Evelyn Kim, Prasad Shirvalkar, Daniel G. Herrera
