Biography Dr. Barreto Chang is an Associate Professor in the Department of Anesthesia and Perioperative Care, with a research focus on understanding the molecular and behavioral basis of cognitive impairment after surgery. By focusing on the perioperative period, she seeks to improve both the information patients receive during the perioperative evaluation in terms of their brain health assessment and also develop potential approaches for neuroprotection during the period of surgery and postoperative recovery. Role Faculty Location UCSF at Mission Bay UCSF at Mount Zion UCSF at Parnassus Category Clinical Research Specialties Neuroanesthesia Education Internship, - Surgery, Stanford Hospital and ClinicsMD/PhD, - Medicine/Neuroscience, Stanford University School of Medicine - Diversity, Equity, and Inclusion Champion Training, University of California San FranciscoPostdoctoral Studies, - Neuroscience, University of California San FranciscoResidency, - Anesthesia, University of California, San FranciscoBS, - Biology, University of Puerto Rico - Mayaguez Publications Training the Next Generation of Anesthesiologists: A Cross-sectional Mixed-methods Study on Mentorship in Anesthesiology. Gisselbaek M, Soriano L, Arnoux S, Seidel L, Schwartz R, Albert A, Berger-Estilita J, Saxena S, Barreto Chang OL . Anesthesiology . Jan 27, 2026 Remote Cognitive Testing for Detection of Baseline Cognitive Impairment and Prediction of Postoperative Delirium Risk: A Pilot Study. Barreto Chang OL, Wise AB, Sinha A, Possin KL, Boxer A, Staffaroni AM, Collaborators . Anesthesia and analgesia . Dec 8, 2025 Emerging biomarkers of postoperative delirium at the intersection of neuroinflammation and neurodegeneration. Leng K, Maze M, Barreto Chang OL . Frontiers in aging neuroscience . Aug 29, 2025 A U.S. based survey of loan burden among anesthesia trainees and its impact on well-being. Pawar N, Boscardin CK, Chen D, Earnest G, Chang OLB . Frontiers in education . Jul 23, 2025 Enhancing early detection of cognitive impairment in primary care with the TabCAT-BHA. Breithaupt AG, Sideman AB, Goode C, Hill-Sakurai L, Premkumar M, Scheffler AW, Chodos A, Tsoy E, Rankin KP, Kramer JH, Bui N, Jarrott S, Gaynor L, Chang OLB, Chow C, Kahn JG, Possin KL . Alzheimer's & dementia : the journal of the Alzheimer's Association . Jul 1, 2025 AI and inclusion in simulation education and leadership: a global cross-sectional evaluation of diversity. Berger-Estilita J, Gisselbaek M, Devos A, Chan A, Ingrassia PL, Meco BC, Chang OLB, Savoldelli GL, Matos FM, Dieckmann P, Østergaard D, Saxena S . Advances in simulation (London, England) . May 4, 2025 Gender Disparities in Artificial Intelligence-Generated Images of Hospital Leadership in the United States. Gisselbaek M, Berger-Estilita J, Minsart L, Köselerli E, Devos A, Matos FM, Barreto Chang OL, Dieckmann P, Suppan M, Saxena S . Mayo Clinic proceedings. Digital health . Apr 8, 2025 A 4-Day Exposure to High Altitude Prolongs QTc in Healthy Human Subjects. Gudelunas K, Chinn GA, Barreto-Chang OL, Campbell L, Sall JW . Wilderness & environmental medicine . Feb 24, 2025 A comparison of large language model-generated and published perioperative neurocognitive disorder recommendations: a cross-sectional web-based analysis. Saxena S, Barreto Chang OL, Suppan M, Meco BC, Vacas S, Radtke F, Matot I, Devos A, Maze M, Gisselbaek M, Berger-Estilita J . British journal of anaesthesia . Feb 7, 2025 ASA Doctors Back to School 2024: The Philly Edition Niti Pawar, MD; Marc Parris, MD, MPH; Odmara L. Barreto Chang, MD, PhD . ASA Monitor . Feb 1, 2025 Closing the Quality Chasm for Brain Health with Implementation Science Odmara L. Barreto Chang MD, PhD; Daniel J. Cole MD, FASA; Robert A. Whittington, MD . ASA Monitor . Jan 7, 2025 Handbook of the Biology and Pathology of Mental Disorders Odmara L. Barreto Chang, Harper S. Kim, and Mervyn Maze . The role of IL-6 Trans-signaling in the pathogenesis of Perioperative Neurocognitive Disorders . Dec 16, 2024 Intraoperative Burst Suppression by Analysis of Raw Electroencephalogram Postoperative Delirium in Older Adults Undergoing Spine Surgery: A Retrospective Cohort Study. Pawar N, Zhou S, Duarte K, Wise A, García PS, Kreuzer M, Barreto Chang OL . Journal of neurosurgical anesthesiology . Nov 19, 2024 Representation of intensivists' race/ethnicity, sex, and age by artificial intelligence: a cross-sectional study of two text-to-image models. Gisselbaek M, Suppan M, Minsart L, Köselerli E, Nainan Myatra S, Matot I, Barreto Chang OL, Saxena S, Berger-Estilita J . Critical care (London, England) . Nov 11, 2024 Beyond the stereotypes: Artificial Intelligence image generation and diversity in anesthesiology. Gisselbaek M, Minsart L, Köselerli E, Suppan M, Meco BC, Seidel L, Albert A, Barreto Chang OL, Saxena S, Berger-Estilita J . Frontiers in artificial intelligence . Oct 9, 2024 Gender and Race/Ethnicity dynamics in anesthesiology mentorship: results of a European survey. Gisselbaek M, Marsh B, Soriano L, Jackman S, Seidel L, Albert A, Matot I, Coppens S, Narouze S, Barreto Chang OL, Saxena S . BMC anesthesiology . Sep 6, 2024 Case Report of Hyponatremic Seizures in a Term Neonate Attributed to Excessive Maternal Coconut Water Ingestion During Labor. Soriano LP, Rollins MD, Barreto Chang OL . A&A practice . Jul 1, 2024 Gender bias in images of anaesthesiologists generated by artificial intelligence. Gisselbaek M, Köselerli E, Suppan M, Minsart L, Meco BC, Seidel L, Albert A, Barreto Chang OL, Berger-Estilita J, Saxena S . British journal of anaesthesia . Jun 27, 2024 Clinical and Medical Innovation in Anesthesiology. Primary book author: Adam E.M. Eltorai. Chapter 15: Pilot Study, Author: Odmara L. Barreto Chang Odmara L. Barreto Chang . Clinical and Medical Innovation in Anesthesiology. Primary book author: Adam E.M. Eltorai. Chapter 15: Pilot Study, Author: Odmara L. Barreto Chang . May 21, 2024 Gaps in cognitive care among older patients undergoing spine surgery. Barreto Chang OL, Pawar N, Whitlock EL, Miller B, Possin KL . Journal of the American Geriatrics Society . Feb 26, 2024 ASA 2023 Doctors Back to School Program Returns to the Classroom Sara Zhou, Darryl P. Brown, and Odmara L. Barreto Chang . . Jan 8, 2024 Association of University Anesthesiologists Odmara L. Barreto Chang and Niti Pawar . The Leaky Pipeline: How Are We Addressing This Problem? . Jan 5, 2024 Impostor syndrome in anaesthesiology primarily affects female and junior physicians☆. Gisselbaek M, Hontoir S, Pesonen AE, Seidel L, Geniets B, Steen E, Barreto Chang OL, Saxena S . British journal of anaesthesia . Oct 25, 2023 Gender equity in anesthesia: is it time to rock the boat? Gisselbaek M, Barreto Chang OL, Saxena S . BMC anesthesiology . Mar 8, 2023 Addressing gaps in primary care diagnosis of cognitive impairment via a telephone-based nurse consultation. Shin SY, Goode CA, Bui NM, Premkumar M, Hill-Sakurai LE, Bernstein Sideman A, Kiekhofer RE, Chodos AH, Dulaney S, Wynn MJ, Barreto Chang OL, Possin KL . Journal of the American Geriatrics Society . Jan 27, 2023 Defining the role of Interleukin-6 for the development of perioperative neurocognitive disorders: Evidence from clinical and preclinical studies. Barreto Chang OL, Maze M . Frontiers in aging neuroscience . Jan 26, 2023 A novel approach for the detection of cognitive impairment and delirium risk in older patients undergoing spine surgery. Barreto Chang OL, Whitlock EL, Arias AD, Tsoy E, Allen IE, Hellman J, Bickler PE, Miller B, Possin KL . Journal of the American Geriatrics Society . Sep 20, 2022 Age-Related Perioperative Neurocognitive Disorders: Experimental Models and Druggable Targets. Barreto Chang OL, Possin KL, Maze M . Annual review of pharmacology and toxicology . Sep 13, 2022 ASA Monitor Christine Vo and Odmara L. Barreto Chang . Moving Forward: 2022 Committee on Professional Diversity's 2nd Virtual Doctors Back to School Program . Sep 1, 2022 Ketamine-Associated Intraoperative Electroencephalographic Signatures of Elderly Patients With and Without Preoperative Cognitive Impairment. Barreto Chang OL, Kreuzer M, Morgen DF, Possin KL, García PS . Anesthesia and analgesia . Jan 20, 2022 Burst Suppression During General Anesthesia and Postoperative Outcomes: Mini Review. Pawar N, Barreto Chang OL . Frontiers in systems neuroscience . Jan 7, 2022 ASA Monitor Odmara L. Barreto Chang, Daniel P. Corsino, Crystal C. Wright . Reaching Out During Challenging Times: The First Virtual Doctors Back to School ProgramTM Event . Jul 23, 2021 A case report: anaphylaxis to cefazolin during renal transplant surgery. Hemati K, Gierat S, Roll GR, Barreto Chang OL . Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology . May 29, 2021 A little help from our friends: intra-operative endoscopy for the extraction of an ingested foreign body. Barreto-Chang O, Palmer O, Ready J, Hwang J . Digestive diseases and sciences . Dec 20, 2011 Diagnosis of pilomatricoma using an otoscope. Barreto-Chang OL, Gorell ES, Yamaguma MA, Lane AT . Pediatric dermatology . Aug 27, 2010 Vitamin D--deficient rickets in a child with cow's milk allergy. Barreto-Chang OL, Barreto-Chang O, Pearson D, Shepard WE, Longhurst CA, Longhurst C, Greene A . Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition . Aug 1, 2010 Regulation of Neuronal Survival and CREB-Dependent Transcription by CaV1.2 L-Type Calcium Channels Barreto-Chang OL . Regulation of Neuronal Survival and CREB-Dependent Transcription by CaV1.2 L-Type Calcium Channels . Apr 1, 2010 Calcium imaging of cortical neurons using Fura-2 AM. Barreto-Chang OL, Dolmetsch RE . Journal of visualized experiments : JoVE . Jan 19, 2009 Parcs is a dual regulator of cell proliferation and apaf-1 function. Sanchez-Olea R, Ortiz S, Barreto O, Yang Q, Xu CJ, Zhu H, Yuan J . The Journal of biological chemistry . Jun 18, 2008 The C terminus of the L-type voltage-gated calcium channel Ca(V)1.2 encodes a transcription factor. Gomez-Ospina N, Tsuruta F, Barreto-Chang O, Hu L, Dolmetsch R . Cell . Nov 3, 2006 Bcl-2 transfection via herpes simplex virus blocks apoptosis-inducing factor translocation after focal ischemia in the rat. Zhao H, Yenari MA, Cheng D, Barreto-Chang OL, Sapolsky RM, Steinberg GK . Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism . Jun 1, 2004
