Odmara Barreto Chang, MD, PhD

Assistant Professor in Residence
What I do: 

I am an assistant professor in residence in the Department of Anesthesia and Perioperative Care.

I pursued a joint MD/PhD program at Stanford University, first completing a PhD in Neurosciences in 2010, before attaining my Medical Degree in 2012.  After spending an additional year as a General Surgery Intern at Stanford, I arrived at UCSF to pursue my Anesthesia Residency, completing the program prior to my faculty appointment. 

My clinical responsibilities are mainly at the Parnassus/Mt Zion/Mission Bay campuses.




Dr. Barreto Chang is an Assistant Professor in the Department of Anesthesia and Perioperative Care, with a research focus on understanding the molecular and behavioral basis of cognitive impairment after surgery. By focusing on the perioperative period, she seeks to improve both the information patients receive during the perioperative evaluation in terms of their brain health assessment and also develop potential approaches for neuroprotection during the period of surgery and postoperative recovery.

Barreto Chang OL, Pawar N, Whitlock EL, Miller B, Possin KL.. Gaps in cognitive care among older patients undergoing spine surgery. J Am Geriatr Soc. 2024; Online ahead of print.
Sara Zhou, Darryl P. Brown, and Odmara L. Barreto Chang. ASA 2023 Doctors Back to School Program Returns to the Classroom. 2024; 88(ASA Monito):32.
Odmara L. Barreto Chang and Niti Pawar. Association of University Anesthesiologists. The Leaky Pipeline: How Are We Addressing This Problem?. 2024; (4):10-12.
Gisselbaek M, Hontoir S, Pesonen AE, Seidel L, Geniets B, Steen E, Barreto Chang OL, Saxena S. Impostor syndrome in anaesthesiology primarily affects female and junior physicians☆. Br J Anaesth. 2024 Feb; 132(2):407-409.
Gisselbaek M, Barreto Chang OL, Saxena S. Gender equity in anesthesia: is it time to rock the boat? BMC Anesthesiol. 2023 03 08; 23(1):67.
Shin SY, Goode CA, Bui NM, Premkumar M, Hill-Sakurai LE, Bernstein Sideman A, Kiekhofer RE, Chodos AH, Dulaney S, Wynn MJ, Barreto Chang OL, Possin KL. Addressing gaps in primary care diagnosis of cognitive impairment via a telephone-based nurse consultation. J Am Geriatr Soc. 2023 06; 71(6):2002-2005.
Barreto Chang OL, Maze M. Defining the role of Interleukin-6 for the development of perioperative neurocognitive disorders: Evidence from clinical and preclinical studies. Front Aging Neurosci. 2022; 14:1097606.
Barreto Chang OL, Whitlock EL, Arias AD, Tsoy E, Allen IE, Hellman J, Bickler PE, Miller B, Possin KL. A novel approach for the detection of cognitive impairment and delirium risk in older patients undergoing spine surgery. J Am Geriatr Soc. 2023 Jan; 71(1):227-234.
Barreto Chang OL, Possin KL, Maze M. Age-Related Perioperative Neurocognitive Disorders: Experimental Models and Druggable Targets. Annu Rev Pharmacol Toxicol. 2022 09 13.
Christine Vo and Odmara L. Barreto Chang. ASA Monitor . Moving Forward: 2022 Committee on Professional Diversity's 2nd Virtual Doctors Back to School Program. 2022; 86(9):32-33.
Barreto Chang OL, Kreuzer M, Morgen DF, Possin KL, García PS. Ketamine-Associated Intraoperative Electroencephalographic Signatures of Elderly Patients With and Without Preoperative Cognitive Impairment. Anesth Analg. 2022 10 01; 135(4):683-692.
Pawar N, Barreto Chang OL. Burst Suppression During General Anesthesia and Postoperative Outcomes: Mini Review. Front Syst Neurosci. 2021; 15:767489.
Odmara L. Barreto Chang, Daniel P. Corsino, Crystal C. Wright. ASA Monitor. Reaching Out During Challenging Times: The First Virtual Doctors Back to School ProgramTM Event. 2021; 85(8):32.
Hemati K, Gierat S, Roll GR, Barreto Chang OL. A case report: anaphylaxis to cefazolin during renal transplant surgery. Allergy Asthma Clin Immunol. 2021 May 29; 17(1):54.
Barreto-Chang O, Palmer O, Ready J, Hwang J. A little help from our friends: intra-operative endoscopy for the extraction of an ingested foreign body. Dig Dis Sci. 2012 Sep; 57(9):2267-9.
Barreto-Chang OL, Gorell ES, Yamaguma MA, Lane AT. Diagnosis of pilomatricoma using an otoscope. Pediatr Dermatol. 2010 Sep-Oct; 27(5):554-7.
Barreto-Chang OL, Barreto-Chang O, Pearson D, Shepard WE, Longhurst CA, Longhurst C, Greene A. Vitamin D--deficient rickets in a child with cow's milk allergy. Nutr Clin Pract. 2010 08; 25(4):394-8.
Barreto-Chang OL. Regulation of Neuronal Survival and CREB-Dependent Transcription by CaV1.2 L-Type Calcium Channels. 2010.
Barreto-Chang OL, Dolmetsch RE. Calcium imaging of cortical neurons using Fura-2 AM. J Vis Exp. 2009 Jan 19; (23).
Sanchez-Olea R, Ortiz S, Barreto O, Yang Q, Xu CJ, Zhu H, Yuan J. Parcs is a dual regulator of cell proliferation and apaf-1 function. J Biol Chem. 2008 Sep 05; 283(36):24400-5.
Gomez-Ospina N, Tsuruta F, Barreto-Chang O, Hu L, Dolmetsch R. The C terminus of the L-type voltage-gated calcium channel Ca(V)1.2 encodes a transcription factor. Cell. 2006 Nov 03; 127(3):591-606.
Zhao H, Yenari MA, Cheng D, Barreto-Chang OL, Sapolsky RM, Steinberg GK. Bcl-2 transfection via herpes simplex virus blocks apoptosis-inducing factor translocation after focal ischemia in the rat. J Cereb Blood Flow Metab. 2004 Jun; 24(6):681-92.
Honors and Awards: 
Harold Amos Medical Faculty Development Program, Robert Wood Johnson Foundation