Michael Rowbotham, MD

Greater recalled pain and movement-evoked pain are associated with longer 400-meter walk and repeat stair climb time: the Study of Muscle, Mobility and Aging.

Mau T, Barnes HN, Simon CB, Hetherington-Rauth M, Bauer SR, Strotmeyer ES, Lane NE, Rowbotham MC, Weaver AA, Blackwell TL, Cai Y, Glynn NW, Goodpaster BH, Cummings SR, Newman AB, Cawthon PM, Kritchevsky SB

Methods for pragmatic randomized clinical trials of pain therapies: IMMPACT statement.

Hohenschurz-Schmidt D, Cherkin D, Rice ASC, Dworkin RH, Turk DC, McDermott MP, Bair MJ, DeBar LL, Edwards RR, Evans SR, Farrar JT, Kerns RD, Rowbotham MC, Wasan AD, Cowan P, Ferguson M, Freeman R, Gewandter JS, Gilron I, Grol-Prokopczyk H, Iyengar S, Kamp C, Karp BI, Kleykamp BA, Loeser JD, Mackey S, Malamut R, McNicol E, Patel KV, Schmader K, Simon L, Steiner DJ, Veasley C, Vollert J

Patient engagement in designing, conducting, and disseminating clinical pain research: IMMPACT recommended considerations.

Haroutounian S, Holzer KJ, Kerns RD, Veasley C, Dworkin RH, Turk DC, Carman KL, Chambers CT, Cowan P, Edwards RR, Eisenach JC, Farrar JT, Ferguson M, Forsythe LP, Freeman R, Gewandter JS, Gilron I, Goertz C, Grol-Prokopczyk H, Iyengar S, Jordan I, Kamp C, Kleykamp BA, Knowles RL, Langford DJ, Mackey S, Malamut R, Markman J, Martin KR, McNicol E, Patel KV, Rice ASC, Rowbotham M, Sandbrink F, Simon LS, Steiner DJ, Vollert J

Research objectives and general considerations for pragmatic clinical trials of pain treatments: IMMPACT statement.

Hohenschurz-Schmidt DJ, Cherkin D, Rice ASC, Dworkin RH, Turk DC, McDermott MP, Bair MJ, DeBar LL, Edwards RR, Farrar JT, Kerns RD, Markman JD, Rowbotham MC, Sherman KJ, Wasan AD, Cowan P, Desjardins P, Ferguson M, Freeman R, Gewandter JS, Gilron I, Grol-Prokopczyk H, Hertz SH, Iyengar S, Kamp C, Karp BI, Kleykamp BA, Loeser JD, Mackey S, Malamut R, McNicol E, Patel KV, Sandbrink F, Schmader K, Simon L, Steiner DJ, Veasley C, Vollert J

Pitfalls and Rewards of Setting Up a Liquid Biopsy Approach for the Detection of Driver Mutations in Circulating Tumor DNAs: Our Institutional Experience.

Chen M, Jian D, Sidorov M, Woo RWL, Kim A, Stone DE, Nazarian A, Nosrati M, Ice RJ, de Semir D, Dar AA, Luštrik R, Kokošar J, Ausec L, Rowbotham MC, Tranah GJ, Kashani-Sabet M, Soroceanu L, McAllister SD, Desprez PY

Optimizing and Accelerating the Development of Precision Pain Treatments for Chronic Pain: IMMPACT Review and Recommendations.

Edwards RR, Schreiber KL, Dworkin RH, Turk DC, Baron R, Freeman R, Jensen TS, Latremoliere A, Markman JD, Rice ASC, Rowbotham M, Staud R, Tate S, Woolf CJ, Andrews NA, Carr DB, Colloca L, Cosma-Roman D, Cowan P, Diatchenko L, Farrar J, Gewandter JS, Gilron I, Kerns RD, Marchand S, Niebler G, Patel KV, Simon LS, Tockarshewsky T, Vanhove GF, Vardeh D, Walco GA, Wasan AD, Wesselmann U

Combination pharmacotherapy for the treatment of neuropathic pain in adults: systematic review and meta-analysis.

Balanaser M, Carley M, Baron R, Finnerup NB, Moore RA, Rowbotham MC, Chaparro LE, Gilron I

Research approaches for evaluating opioid sparing in clinical trials of acute and chronic pain treatments: Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials recommendations.

Gewandter JS, Smith SM, Dworkin RH, Turk DC, Gan TJ, Gilron I, Hertz S, Katz NP, Markman JD, Raja SN, Rowbotham MC, Stacey BR, Strain EC, Ward DS, Farrar JT, Kroenke K, Rathmell JP, Rauck R, Brown C, Cowan P, Edwards RR, Eisenach JC, Ferguson M, Freeman R, Gray R, Giblin K, Grol-Prokopczyk H, Haythornthwaite J, Jamison RN, Martel M, McNicol E, L Oshinsky M, Sandbrink F, Scholz J, Scranton R, Simon LS, Steiner D, Verburg K, Wasan AD, Wentworth K

Benefit-risk assessment and reporting in clinical trials of chronic pain treatments: IMMPACT recommendations.

Kleykamp BA, Dworkin RH, Turk DC, Bhagwagar Z, Cowan P, Eccleston C, Ellenberg SS, Evans SR, Farrar JT, Freeman RL, Garrison LP, Gewandter JS, Goli V, Iyengar S, Jadad AR, Jensen MP, Junor R, Katz NP, Kesslak JP, Kopecky EA, Lissin D, Markman JD, McDermott MP, Mease PJ, O'Connor AB, Patel KV, Raja SN, Rowbotham MC, Sampaio C, Singh JA, Steigerwald I, Strand V, Tive LA, Tobias J, Wasan AD, Wilson HD

Cannabinoids, cannabis, and cannabis-based medicine for pain management: a systematic review of randomised controlled trials.

Fisher E, Moore RA, Fogarty AE, Finn DP, Finnerup NB, Gilron I, Haroutounian S, Krane E, Rice ASC, Rowbotham M, Wallace M, Eccleston C

Cannabinoids, cannabis, and cannabis-based medicines for pain management: an overview of systematic reviews.

Moore RA, Fisher E, Finn DP, Finnerup NB, Gilron I, Haroutounian S, Krane E, Rice ASC, Rowbotham M, Wallace M, Eccleston C

International Association for the Study of Pain Presidential Task Force on Cannabis and Cannabinoid Analgesia: research agenda on the use of cannabinoids, cannabis, and cannabis-based medicines for pain management.

Haroutounian S, Arendt-Nielsen L, Belton J, Blyth FM, Degenhardt L, Di Forti M, Eccleston C, Finn DP, Finnerup NB, Fisher E, Fogarty AE, Gilron I, Hohmann AG, Kalso E, Krane E, Mohiuddin M, Moore RA, Rowbotham M, Soliman N, Wallace M, Zinboonyahgoon N, Rice ASC

Societal issues and policy implications related to the use of cannabinoids, cannabis, and cannabis-based medicines for pain management.

Haroutounian S, Gilron I, Belton J, Degenhardt L, Di Forti M, Finn DP, Fogarty A, Kalso E, Krane E, Moore RA, Rowbotham M, Wallace M, Rice ASC

A year like no other: introduction to a special issue on COVID-19 and pain.

Rowbotham MC, Arendt-Nielsen L

Interpretation of chronic pain clinical trial outcomes: IMMPACT recommended considerations.

Smith SM, Dworkin RH, Turk DC, McDermott MP, Eccleston C, Farrar JT, Rowbotham MC, Bhagwagar Z, Burke LB, Cowan P, Ellenberg SS, Evans SR, Freeman RL, Garrison LP, Iyengar S, Jadad A, Jensen MP, Junor R, Kamp C, Katz NP, Kesslak JP, Kopecky EA, Lissin D, Markman JD, Mease PJ, O'Connor AB, Patel KV, Raja SN, Sampaio C, Schoenfeld D, Singh J, Steigerwald I, Strand V, Tive LA, Tobias J, Wasan AD, Wilson HD

Evolution of Analgesic Tolerance and Opioid-Induced Hyperalgesia Over 6 Months: Double-Blind Randomized Trial Incorporating Experimental Pain Models.

Rowbotham MC, Wallace M

Improving Study Conduct and Data Quality in Clinical Trials of Chronic Pain Treatments: IMMPACT Recommendations.

Gewandter JS, Dworkin RH, Turk DC, Devine EG, Hewitt D, Jensen MP, Katz NP, Kirkwood AA, Malamut R, Markman JD, Vrijens B, Burke L, Campbell JN, Carr DB, Conaghan PG, Cowan P, Doyle MK, Edwards RR, Evans SR, Farrar JT, Freeman R, Gilron I, Juge D, Kerns RD, Kopecky EA, McDermott MP, Niebler G, Patel KV, Rauck R, Rice ASC, Rowbotham M, Sessler NE, Simon LS, Singla N, Skljarevski V, Tockarshewsky T, Vanhove GF, Wasan AD, Witter J

SUMMIT-07: a randomized trial of NKTR-181, a new molecular entity, full mu-opioid receptor agonist for chronic low-back pain.

Markman J, Gudin J, Rauck R, Argoff C, Rowbotham M, Agaiby E, Gimbel J, Katz N, Doberstein SK, Tagliaferri M, Lu L, Siddhanti S, Hale M

Cannabinoids, cannabis, and cannabis-based medicine for pain management: a protocol for an overview of systematic reviews and a systematic review of randomised controlled trials.

Fisher E, Eccleston C, Degenhardt L, Finn DP, Finnerup NB, Gilron I, Haroutounian S, Krane E, Rice ASC, Rowbotham M, Wallace M, Moore RA

The IASP classification of chronic pain for ICD-11: chronic neuropathic pain.

Scholz J, Finnerup NB, Attal N, Aziz Q, Baron R, Bennett MI, Benoliel R, Cohen M, Cruccu G, Davis KD, Evers S, First M, Giamberardino MA, Hansson P, Kaasa S, Korwisi B, Kosek E, Lavand'homme P, Nicholas M, Nurmikko T, Perrot S, Raja SN, Rice ASC, Rowbotham MC, Schug S, Simpson DM, Smith BH, Svensson P, Vlaeyen JWS, Wang SJ, Barke A, Rief W, Treede RD, Classification Committee of the Neuropathic Pain Special Interest Group (NeuPSIG)

Evaluation of composite responder outcomes of pain intensity and physical function in neuropathic pain clinical trials: an ACTTION individual patient data analysis.

Patel KV, Allen R, Burke L, Farrar JT, Gewandter JS, Gilron I, Katz NP, Markman JD, Marshall SF, Resnick M, Rice ASC, Rowbotham MC, Smith SM, Vanhove GF, Wasan AD, Zhang S, Dworkin RH, Turk DC

Natural history of pain associated with melanoma surgery.

Slagelse C, Munch T, Glazer C, Greene K, Finnerup NB, Kashani-Sabet M, Leong SP, Petersen KL, Rowbotham MC

Ethical considerations in the design, execution, and analysis of clinical trials of chronic pain treatments.

Rowbotham MC, McDermott MP

The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions.

Kent ML, Tighe PJ, Belfer I, Brennan TJ, Bruehl S, Brummett CM, Buckenmaier CC, Buvanendran A, Cohen RI, Desjardins P, Edwards D, Fillingim R, Gewandter J, Gordon DB, Hurley RW, Kehlet H, Loeser JD, Mackey S, McLean SA, Polomano R, Rahman S, Raja S, Rowbotham M, Suresh S, Schachtel B, Schreiber K, Schumacher M, Stacey B, Stanos S, Todd K, Turk DC, Weisman SJ, Wu C, Carr DB, Dworkin RH, Terman G

The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions.

Kent ML, Tighe PJ, Belfer I, Brennan TJ, Bruehl S, Brummett CM, Buckenmaier CC, Buvanendran A, Cohen RI, Desjardins P, Edwards D, Fillingim R, Gewandter J, Gordon DB, Hurley RW, Kehlet H, Loeser JD, Mackey S, McLean SA, Polomano R, Rahman S, Raja S, Rowbotham M, Suresh S, Schachtel B, Schreiber K, Schumacher M, Stacey B, Stanos S, Todd K, Turk DC, Weisman SJ, Wu C, Carr DB, Dworkin RH, Terman G

Informed Consent.

Grady C, Cummings SR, Rowbotham MC, McConnell MV, Ashley EA, Kang G

The Potential Role of Sensory Testing, Skin Biopsy, and Functional Brain Imaging as Biomarkers in Chronic Pain Clinical Trials: IMMPACT Considerations.

Smith SM, Dworkin RH, Turk DC, Baron R, Polydefkis M, Tracey I, Borsook D, Edwards RR, Harris RE, Wager TD, Arendt-Nielsen L, Burke LB, Carr DB, Chappell A, Farrar JT, Freeman R, Gilron I, Goli V, Haeussler J, Jensen T, Katz NP, Kent J, Kopecky EA, Lee DA, Maixner W, Markman JD, McArthur JC, McDermott MP, Parvathenani L, Raja SN, Rappaport BA, Rice ASC, Rowbotham MC, Tobias JK, Wasan AD, Witter J

Reporting of data monitoring boards in publications of randomized clinical trials is often deficient: ACTTION systematic review.

Gewandter JS, Kitt RA, Hunsinger MR, Poku J, Lozano J, Chaudari J, Evans S, Gross RA, McDermott MP, Rowbotham MC, Turk DC, Dworkin RH

Adverse Event Reporting in Clinical Trials of Intravenous and Invasive Pain Treatments: An ACTTION Systematic Review.

Williams MR, McKeown A, Pressman Z, Hunsinger M, Lee K, Coplan P, Gilron I, Katz NP, McDermott MP, Raja SN, Rappaport BA, Rowbotham MC, Turk DC, Dworkin RH, Smith SM

Mitochondrial DNA Heteroplasmy Associations With Neurosensory and Mobility Function in Elderly Adults.

Tranah GJ, Yaffe K, Katzman SM, Lam ET, Pawlikowska L, Kwok PY, Schork NJ, Manini TM, Kritchevsky S, Thomas F, Newman AB, Harris TB, Coleman AL, Gorin MB, Helzner EP, Rowbotham MC, Browner WS, Cummings SR, Health, Aging and Body Composition Study

Tricyclic antidepressants and opioids-better together?

Rowbotham MC

Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis.

Finnerup NB, Attal N, Haroutounian S, McNicol E, Baron R, Dworkin RH, Gilron I, Haanpää M, Hansson P, Jensen TS, Kamerman PR, Lund K, Moore A, Raja SN, Rice AS, Rowbotham M, Sena E, Siddall P, Smith BH, Wallace M

Results availability for analgesic device, complex regional pain syndrome, and post-stroke pain trials: comparing the RReADS, RReACT, and RReMiT databases.

Dufka FL, Munch T, Dworkin RH, Rowbotham MC

Reporting of sample size calculations in analgesic clinical trials: ACTTION systematic review.

McKeown A, Gewandter JS, McDermott MP, Pawlowski JR, Poli JJ, Rothstein D, Farrar JT, Gilron I, Katz NP, Lin AH, Rappaport BA, Rowbotham MC, Turk DC, Dworkin RH, Smith SM

Data interpretation in analgesic clinical trials with statistically nonsignificant primary analyses: an ACTTION systematic review.

Gewandter JS, McKeown A, McDermott MP, Dworkin JD, Smith SM, Gross RA, Hunsinger M, Lin AH, Rappaport BA, Rice AS, Rowbotham MC, Williams MR, Turk DC, Dworkin RH

Reporting of intention-to-treat analyses in recent analgesic clinical trials: ACTTION systematic review and recommendations.

Gewandter JS, McDermott MP, McKeown A, Smith SM, Pawlowski JR, Poli JJ, Rothstein D, Williams MR, Bujanover S, Farrar JT, Gilron I, Katz NP, Rowbotham MC, Turk DC, Dworkin RH

How transparent are migraine clinical trials? Repository of Registered Migraine Trials (RReMiT).

Dufka FL, Dworkin RH, Rowbotham MC

Research designs for proof-of-concept chronic pain clinical trials: IMMPACT recommendations.

Gewandter JS, Dworkin RH, Turk DC, McDermott MP, Baron R, Gastonguay MR, Gilron I, Katz NP, Mehta C, Raja SN, Senn S, Taylor C, Cowan P, Desjardins P, Dimitrova R, Dionne R, Farrar JT, Hewitt DJ, Iyengar S, Jay GW, Kalso E, Kerns RD, Leff R, Leong M, Petersen KL, Ravina BM, Rauschkolb C, Rice ASC, Rowbotham MC, Sampaio C, Sindrup SH, Stauffer JW, Steigerwald I, Stewart J, Tobias J, Treede RD, Wallace M, White RE

Effect of variability in the 7-day baseline pain diary on the assay sensitivity of neuropathic pain randomized clinical trials: an ACTTION study.

Farrar JT, Troxel AB, Haynes K, Gilron I, Kerns RD, Katz NP, Rappaport BA, Rowbotham MC, Tierney AM, Turk DC, Dworkin RH

RReACT goes global: perils and pitfalls of constructing a global open-access database of registered analgesic clinical trials and trial results.

Munch T, Dufka FL, Greene K, Smith SM, Dworkin RH, Rowbotham MC

Persistent postoperative pain and sensory changes following lymph node excision in melanoma patients: a topical review.

Slagelse C, Petersen KL, Dahl JB, Finnerup K, Greene K, Leong SP, Levine J, Rowbotham M, Werner MU, Finnerup NB

Correction: Shaped Magnetic Field Pulses by Multi-Coil Repetitive Transcranial Magnetic Stimulation (rTMS) Differentially Modulate Anterior Cingulate Cortex Responses and Pain in Volunteers and Fibromyalgia Patients.

Tzabazis A, Aparici CM, Rowbotham MC, Schneider MB, Etkin A, Yeomans DC

Abuse liability measures for use in analgesic clinical trials in patients with pain: IMMPACT recommendations.

O'Connor AB, Turk DC, Dworkin RH, Katz NP, Colucci R, Haythornthwaite JA, Klein M, O'Brien C, Posner K, Rappaport BA, Reisfield G, Adams EH, Balster RL, Bigelow GE, Burke LB, Comer SD, Cone E, Cowan P, Denisco RA, Farrar JT, Foltin RW, Haddox DJ, Hertz S, Jay GW, Junor R, Kopecky EA, Leiderman DB, McDermott MP, Palmer PP, Raja SN, Rauschkolb C, Rowbotham MC, Sampaio C, Setnik B, Smith SM, Sokolowska M, Stauffer JW, Walsh SL, Zacny JP

Discrepancies between registered and published primary outcome specifications in analgesic trials: ACTTION systematic review and recommendations.

Smith SM, Wang AT, Pereira A, Chang DR, McKeown A, Greene K, Rowbotham MC, Burke LB, Coplan P, Gilron I, Hertz SH, Katz NP, Lin AH, McDermott MP, Papadopoulos EJ, Rappaport BA, Sweeney M, Turk DC, Dworkin RH

Shaped magnetic field pulses by multi-coil repetitive transcranial magnetic stimulation (rTMS) differentially modulate anterior cingulate cortex responses and pain in volunteers and fibromyalgia patients.

Tzabazis A, Aparici CM, Rowbotham MC, Schneider MB, Etkin A, Yeomans DC

Does naloxone reinstate secondary hyperalgesia in humans after resolution of a burn injury? A placebo-controlled, double-blind, randomized, cross-over study.

Pereira MP, Werner MU, Ringsted TK, Rowbotham MC, Taylor BK, Dahl JB

Assay sensitivity and study features in neuropathic pain trials: an ACTTION meta-analysis.

Dworkin RH, Turk DC, Peirce-Sandner S, He H, McDermott MP, Farrar JT, Katz NP, Lin AH, Rappaport BA, Rowbotham MC

Healthy volunteers can be phenotyped using cutaneous sensitization pain models.

Werner MU, Petersen KL, Rowbotham MC, Dahl JB

Natural history of herpes zoster: late follow-up of 3.9 years (n=43) and 7.7 years (n=10).

Reda H, Greene K, Rice FL, Rowbotham MC, Petersen KL

Adverse event assessment, analysis, and reporting in recent published analgesic clinical trials: ACTTION systematic review and recommendations.

Smith SM, Wang AT, Katz NP, McDermott MP, Burke LB, Coplan P, Gilron I, Hertz SH, Lin AH, Rappaport BA, Rowbotham MC, Sampaio C, Sweeney M, Turk DC, Dworkin RH

Can pragmatic trials help us better understand chronic pain and improve treatment?

Rowbotham MC, Gilron I, Glazer C, Rice ASC, Smith BH, Stewart WF, Wasan AD

Interactive informed consent: randomized comparison with paper consents.

Rowbotham MC, Astin J, Greene K, Cummings SR

Neuropathic pain needs systematic classification.

Finnerup NB, Scholz J, Attal N, Baron R, Haanpää M, Hansson P, Raja SN, Rice AS, Rief W, Rowbotham MC, Simpson DM, Treede RD

Core outcome measures for opioid abuse liability laboratory assessment studies in humans: IMMPACT recommendations.

Comer SD, Zacny JP, Dworkin RH, Turk DC, Bigelow GE, Foltin RW, Jasinski DR, Sellers EM, Adams EH, Balster R, Burke LB, Cerny I, Colucci RD, Cone E, Cowan P, Farrar JT, Haddox DJ, Haythornthwaite JA, Hertz S, Jay GW, Johanson CE, Junor R, Katz NP, Klein M, Kopecky EA, Leiderman DB, McDermott MP, O'Brien C, O'Connor AB, Palmer PP, Raja SN, Rappaport BA, Rauschkolb C, Rowbotham MC, Sampaio C, Setnik B, Sokolowska M, Stauffer JW, Walsh SL

Adherence to CONSORT harms-reporting recommendations in publications of recent analgesic clinical trials: an ACTTION systematic review.

Smith SM, Chang DR, Pereira A, Shah N, Gilron I, Katz NP, Lin AH, McDermott MP, Rappaport BA, Rowbotham MC, Sampaio C, Turk DC, Dworkin RH

A snapshot and scorecard for analgesic clinical trials for chronic pain: the RReACT database.

Greene K, Dworkin RH, Rowbotham MC

Randomized control trial of topical clonidine for treatment of painful diabetic neuropathy.

Campbell CM, Kipnes MS, Stouch BC, Brady KL, Kelly M, Schmidt WK, Petersen KL, Rowbotham MC, Campbell JN

Considerations for improving assay sensitivity in chronic pain clinical trials: IMMPACT recommendations.

Dworkin RH, Turk DC, Peirce-Sandner S, Burke LB, Farrar JT, Gilron I, Jensen MP, Katz NP, Raja SN, Rappaport BA, Rowbotham MC, Backonja MM, Baron R, Bellamy N, Bhagwagar Z, Costello A, Cowan P, Fang WC, Hertz S, Jay GW, Junor R, Kerns RD, Kerwin R, Kopecky EA, Lissin D, Malamut R, Markman JD, McDermott MP, Munera C, Porter L, Rauschkolb C, Rice ASC, Sampaio C, Skljarevski V, Sommerville K, Stacey BR, Steigerwald I, Tobias J, Trentacosti AM, Wasan AD, Wells GA, Williams J, Witter J, Ziegler D

Efficacy and safety of the α4β2 neuronal nicotinic receptor agonist ABT-894 in patients with diabetic peripheral neuropathic pain.

Rowbotham MC, Arslanian A, Nothaft W, Duan RW, Best AE, Pritchett Y, Zhou Q, Stacey BR

How to reduce the incidence of neuropathic pain: sentinel node biopsy for diagnosis of metastatic malignant melanoma.

Rowbotham MC, Leong SPL

Oral and cutaneous thermosensory profile of selective TRPV1 inhibition by ABT-102 in a randomized healthy volunteer trial.

Rowbotham MC, Nothaft W, Duan RW, Wang Y, Faltynek C, McGaraughty S, Chu KL, Svensson P

Effect of a single dose of pregabalin on herpes zoster pain.

Jensen-Dahm C, Rowbotham MC, Reda H, Petersen KL

Evidence-based clinical trial design for chronic pain pharmacotherapy: a blueprint for ACTION.

Dworkin RH, Turk DC, Katz NP, Rowbotham MC, Peirce-Sandner S, Cerny I, Clingman CS, Eloff BC, Farrar JT, Kamp C, McDermott MP, Rappaport BA, Sanhai WR

NeuPSIG guidelines on neuropathic pain assessment.

Haanpää M, Attal N, Backonja M, Baron R, Bennett M, Bouhassira D, Cruccu G, Hansson P, Haythornthwaite JA, Iannetti GD, Jensen TS, Kauppila T, Nurmikko TJ, Rice ASC, Rowbotham M, Serra J, Sommer C, Smith BH, Treede RD

Natural history of cutaneous innervation following herpes zoster.

Petersen KL, Rice FL, Farhadi M, Reda H, Rowbotham MC

Natural history of sensory function after herpes zoster.

Petersen KL, Rowbotham MC

Opioid pharmacotherapy for chronic non-cancer pain in the United States: a research guideline for developing an evidence-base.

Chapman CR, Lipschitz DL, Angst MS, Chou R, Denisco RC, Donaldson GW, Fine PG, Foley KM, Gallagher RM, Gilson AM, Haddox JD, Horn SD, Inturrisi CE, Jick SS, Lipman AG, Loeser JD, Noble M, Porter L, Rowbotham MC, Schoelles KM, Turk DC, Volinn E, Von Korff MR, Webster LR, Weisner CM

Pain's policy on the spinal administration of drugs.

Rowbotham MC

The case for publishing 'negative' clinical trials.

Rowbotham MC

Clinical effectiveness: an approach to clinical trial design more relevant to clinical practice, acknowledging the importance of individual differences.

Moore RA, Derry S, McQuay HJ, Straube S, Aldington D, Wiffen P, Bell RF, Kalso E, Rowbotham MC, ACTINPAIN writing group of the IASP Special Interest Group (SIG) on Systematic Reviews in Pain Relie

A randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of ABT-594 in patients with diabetic peripheral neuropathic pain.

Rowbotham MC, Duan RW, Thomas J, Nothaft W, Backonja MM

Predicting therapeutic efficacy - experimental pain in human subjects.

Chizh BA, Priestley T, Rowbotham M, Schaffler K

The impact of selective publication on clinical research in pain.

Rowbotham MC

Naltrexone aversion and treatment efficacy are greatest in humans and rats that actively consume high levels of alcohol.

Mitchell JM, Bergren LJ, Chen KS, Rowbotham MC, Fields HL

How should treatment results from clinical practice be reported?

Rowbotham MC

Placebo response in neuropathic pain trials.

Quessy SN, Rowbotham MC

Pregabalin for postherpetic neuralgia: placebo-controlled trial of fixed and flexible dosing regimens on allodynia and time to onset of pain relief.

Stacey BR, Barrett JA, Whalen E, Phillips KF, Rowbotham MC

Changes in morphine analgesia and side effects during daily subcutaneous administration in healthy volunteers.

Petersen KL, Meadoff T, Press S, Peters MM, LeComte MD, Rowbotham MC

How effective is long-term opioid therapy for chronic noncancer pain?

Rowbotham MC, Lindsey CD

Relief of post-herpetic neuralgia by surgical removal of painful skin: 5 years later.

Petersen KL, Rowbotham MC

Cannabis in painful HIV-associated sensory neuropathy: a randomized placebo-controlled trial.

Abrams DI, Jay CA, Shade SB, Vizoso H, Reda H, Press S, Kelly ME, Rowbotham MC, Petersen KL

The Asp40 mu-opioid receptor allele does not predict naltrexone treatment efficacy in heavy drinkers.

Mitchell JM, Fields HL, White RL, Meadoff TM, Joslyn G, Rowbotham MC

Duloxetine for the management of diabetic peripheral neuropathic pain: evidence-based findings from post hoc analysis of three multicenter, randomized, double-blind, placebo-controlled, parallel-group studies.

Kajdasz DK, Iyengar S, Desaiah D, Backonja MM, Farrar JT, Fishbain DA, Jensen TS, Rowbotham MC, Sang CN, Ziegler D, McQuay HJ

Recommendations for the management of herpes zoster.

Dworkin RH, Johnson RW, Breuer J, Gnann JW, Levin MJ, Backonja M, Betts RF, Gershon AA, Haanpaa ML, McKendrick MW, Nurmikko TJ, Oaklander AL, Oxman MN, Pavan-Langston D, Petersen KL, Rowbotham MC, Schmader KE, Stacey BR, Tyring SK, van Wijck AJ, Wallace MS, Wassilew SW, Whitley RJ

Placebo-controlled comparison of a morphine/dextromethorphan combination with morphine on experimental pain and hyperalgesia in healthy volunteers.

Frymoyer AR, Rowbotham MC, Petersen KL

Natural history of pain following herpes zoster.

Thyregod HG, Rowbotham MC, Peters M, Possehn J, Berro M, Petersen KL

Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients.

Leung JM, Sands LP, Rico M, Petersen KL, Rowbotham MC, Dahl JB, Ames C, Chou D, Weinstein P

Quantitative sensory testing scaled up for multicenter clinical research networks: a promising start.

Petersen KL, Rowbotham MC

Pharmacologic management of complex regional pain syndrome.

Rowbotham MC

Mechanisms of neuropathic pain and their implications for the design of clinical trials.

Rowbotham MC

Treatment response in antidepressant-naïve postherpetic neuralgia patients: double-blind, randomized trial.

Rowbotham MC, Reisner LA, Davies PS, Fields HL

Does pain change the brain?

Birklein F, Rowbotham MC

Is fibromyalgia a neuropathic pain syndrome?

Rowbotham MC

Pregabalin for the treatment of fibromyalgia syndrome: results of a randomized, double-blind, placebo-controlled trial.

Crofford LJ, Rowbotham MC, Mease PJ, Russell IJ, Dworkin RH, Corbin AE, Young JP, LaMoreaux LK, Martin SA, Sharma U, Pregabalin 1008-105 Study Group

Venlafaxine extended release in the treatment of painful diabetic neuropathy: a double-blind, placebo-controlled study.

Rowbotham MC, Goli V, Kunz NR, Lei D

Complex regional pain syndrome-like symptoms during herpes zoster.

Berry JD, Rowbotham MC, Petersen KL

Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations.

Dworkin RH, Backonja M, Rowbotham MC, Allen RR, Argoff CR, Bennett GJ, Bushnell MC, Farrar JT, Galer BS, Haythornthwaite JA, Hewitt DJ, Loeser JD, Max MB, Saltarelli M, Schmader KE, Stein C, Thompson D, Turk DC, Wallace MS, Watkins LR, Weinstein SM

Pilot tolerability and effectiveness study of levetiracetam for postherpetic neuralgia.

Rowbotham MC, Manville NS, Ren J

A randomized study of the effect of oral lamotrigine and hydromorphone on pain and hyperalgesia following heat/capsaicin sensitization.

Petersen KL, Maloney A, Hoke F, Dahl JB, Rowbotham MC

Oral opioid therapy for chronic peripheral and central neuropathic pain.

Rowbotham MC, Twilling L, Davies PS, Reisner L, Taylor K, Mohr D

A randomized, double-blind, placebo-controlled trial of a glycine antagonist in neuropathic pain.

Wallace MS, Rowbotham MC, Katz NP, Dworkin RH, Dotson RM, Galer BS, Rauck RL, Backonja MM, Quessy SN, Meisner PD

The lidocaine patch 5% effectively treats all neuropathic pain qualities: results of a randomized, double-blind, vehicle-controlled, 3-week efficacy study with use of the neuropathic pain scale.

Galer BS, Jensen MP, Ma T, Davies PS, Rowbotham MC

Gabapentin suppresses cutaneous hyperalgesia following heat-capsaicin sensitization.

Dirks J, Petersen KL, Rowbotham MC, Dahl JB

Relief of post-herpetic neuralgia by surgical removal of painful skin.

Petersen KL, Rice FL, Suess F, Berro M, Rowbotham MC

A multicenter, double-blind, randomized, placebo-controlled crossover evaluation of a short course of 4030W92 in patients with chronic neuropathic pain.

Wallace MS, Rowbotham M, Bennett GJ, Jensen TS, Pladna R, Quessy S

Systemic absorption of topical lidocaine in normal volunteers, patients with post-herpetic neuralgia, and patients with acute herpes zoster.

Campbell BJ, Rowbotham M, Davies PS, Jacob P, Benowitz NL

What is a "clinically meaningful" reduction in pain?

Rowbotham MC

Effect of systemic adenosine on pain and secondary hyperalgesia associated with the heat/capsaicin sensitization model in healthy volunteers.

Dirks J, Petersen KL, Rowbotham MC, Dahl JB

Zoster-associated pain and neural dysfunction.

Rowbotham MC, Petersen KL

Effect of intravenous magnesium on pain and secondary hyperalgesia associated with the heat/capsaicin sensitization model in healthy volunteers.

Mikkelsen S, Dirks J, Fabricius P, Petersen KL, Rowbotham MC, Dahl JB

Effect of remifentanil on pain and secondary hyperalgesia associated with the heat--capsaicin sensitization model in healthy volunteers.

Petersen KL, Jones B, Segredo V, Dahl JB, Rowbotham MC

Capsaicin evoked pain and allodynia in post-herpetic neuralgia.

Petersen KL, Fields HL, Brennum J, Sandroni P, Rowbotham MC

Lack of efficacy of riluzole in the treatment of peripheral neuropathic pain conditions.

Galer BS, Twilling LL, Harle J, Cluff RS, Friedman E, Rowbotham MC

The effect of systemic lidocaine on pain and secondary hyperalgesia associated with the heat/capsaicin sensitization model in healthy volunteers.

Dirks J, Fabricius P, Petersen KL, Rowbotham MC, Dahl JB

Will ion-channel blockers be useful for management of nonneuropathic pain?

Petersen KL, Rowbotham MC

Herpes zoster.

Dworkin RH, Galer BS, Rowbotham MC

Topical diclofenac patch relieves minor sports injury pain: results of a multicenter controlled clinical trial.

Galer BS, Rowbotham M, Perander J, Devers A, Friedman E

Quantitation of levorphanol in human plasma at subnanogram per milliliter levels using capillary gas chromatography with electron-capture detection.

Everhart ET, Shwonek P, Jacob P, Rowbotham MC, Jones RT

A new human experimental pain model: the heat/capsaicin sensitization model.

Petersen KL, Rowbotham MC

Topical lidocaine patch relieves postherpetic neuralgia more effectively than a vehicle topical patch: results of an enriched enrollment study.

Galer BS, Rowbotham MC, Perander J, Friedman E

Effect of sympathetic activity on capsaicin-evoked pain, hyperalgesia, and vasodilatation.

Baron R, Wasner G, Borgstedt R, Hastedt E, Schulte H, Binder A, Kopper F, Rowbotham M, Levine JD, Fields HL

Effect of EMLA pre-treatment on capsaicin-induced burning and hyperalgesia.

Yosipovitch G, Maibach HI, Rowbotham MC

Cocaine metabolite kinetics in the newborn.

Dempsey D, Jacob P, Partridge JC, Jones RT, Panganiban K, Rowbotham MC

Gabapentin for the treatment of postherpetic neuralgia: a randomized controlled trial.

Rowbotham M, Harden N, Stacey B, Bernstein P, Magnus-Miller L

Pain caused by herpes zoster infection.

Cluff RS, Rowbotham MC

Postherpetic neuralgia: irritable nociceptors and deafferentation.

Fields HL, Rowbotham M, Baron R

Complex regional pain syndrome type I (reflex sympathetic dystrophy): more than a myth.

Rowbotham MC

Cocaine, nicotine, caffeine, and metabolite plasma concentrations in neonates.

Dempsey DA, Partridge JC, Jones RT, Rowbotham MC

Effect of adrenergic receptor activation on post-herpetic neuralgia pain and sensory disturbances.

Choi B, Rowbotham MC

Response to intravenous lidocaine infusion predicts subsequent response to oral mexiletine: a prospective study.

Galer BS, Harle J, Rowbotham MC

Venlafaxine hydrochloride and chronic pain.

Taylor K, Rowbotham MC

Lidocaine patch: double-blind controlled study of a new treatment method for post-herpetic neuralgia.

Rowbotham MC, Davies PS, Verkempinck C, Galer BS

The relationship of pain, allodynia and thermal sensation in post-herpetic neuralgia.

Rowbotham MC, Fields HL

Cutaneous innervation density in the allodynic form of postherpetic neuralgia.

Rowbotham MC, Yosipovitch G, Connolly MK, Finlay D, Forde G, Fields HL

Chronic pain: from theory to practical management.

Rowbotham MC

Topical lidocaine gel relieves postherpetic neuralgia.

Rowbotham MC, Davies PS, Fields HL

The interpretation of pain relief and sensory changes following sympathetic blockade.

Dellemijn PL, Fields HL, Allen RR, McKay WR, Rowbotham MC

Postherpetic neuralgia.

Rowbotham MC

Managing post-herpetic neuralgia with opioids and local anesthetics.

Rowbotham MC

Response to intravenous lidocaine infusion differs based on clinical diagnosis and site of nervous system injury.

Galer BS, Miller KV, Rowbotham MC

Treatment of postherpetic neuralgia.

Rowbotham MC

Treatment of inflammatory, neuropathic and sympathetically maintained pain in a patient with Sjögren's syndrome.

Galer BS, Rowbotham MC, Miller KV, Walton A, Fields HL

Both intravenous lidocaine and morphine reduce the pain of postherpetic neuralgia.

Rowbotham MC, Reisner-Keller LA, Fields HL

Neurologic consequences of cocaine use.

Rowbotham MC, Lowenstein DH

Post-herpetic neuralgia: the relation of pain complaint, sensory disturbance, and skin temperature.

Rowbotham MC, Fields HL

Topical lidocaine reduces pain in post-herpetic neuralgia.

Rowbotham MC, Fields HL

Thalamomesencephalic strokes after cocaine abuse.

Rowley HA, Lowenstein DH, Rowbotham MC, Simon RP

Neurologic aspects of cocaine abuse.

Rowbotham MC

Acute neurologic and psychiatric complications associated with cocaine abuse.

Lowenstein DH, Massa SM, Rowbotham MC, Collins SD, McKinney HE, Simon RP

Cocaine-calcium channel antagonist interactions.

Rowbotham MC, Hooker WD, Mendelson J, Jones RT

Trazodone-oral cocaine interactions.

Rowbotham MC, Jones RT, Benowitz NL, Jacob P

Failure of naloxone to reverse apomorphine effects in humans.

Rowbotham MC, Joseph MS, Jones RT, Keil LC

Michael Rowbotham, MD

Publications