Michael Bokoch, MD, PhD

Associate Prof of Anesthesia
Hillary Braun, Alex T Fields, Kim Rodriguez, Zachary A Matthay, Rishi Kothari, Claus U Niemann, Dieter Adelmann, Nancy L Ascher, John P Roberts, Michael P Bokoch, Lucy Z Kornblith. P2.02: Save the Environment: Liver Transplantation Restores A Circulating Environment That Supports Healthy Platelet Aggregation Within Two Hours of Reperfusion. Transplantation. 2022 Sep 13; 106(9S):s505-s506.
Legrand M, Bagshaw SM, Koyner JL, Schulman IH, Mathis MR, Bernholz J, Coca S, Gallagher M, Gaudry S, Liu KD, Mehta RL, Pirracchio R, Ryan A, Steubl D, Stockbridge N, Erlandsson F, Turan A, Wilson FP, Zarbock A, Bokoch MP, Casey JD, Rossignol P, Harhay MO. Optimizing the Design and Analysis of Future AKI Trials. J Am Soc Nephrol. 2022 08; 33(8):1459-1470.
Legrand M, Bokoch MP. The Yin and Yang of the Renin-Angiotensin-Aldosterone System in Acute Kidney Injury. Am J Respir Crit Care Med. 2021 05 01; 203(9):1053-1055.
Hannon V, Kothari RP, Zhang L, Bokoch MP, Hill R, Roll GR, Mello A, Feiner JR, Liu KD, Niemann CU, Adelmann D. The Association Between Vena Cava Implantation Technique and Acute Kidney Injury After Liver Transplantation. Transplantation. 2020 11; 104(11):e308-e316.
Bokoch MP, Findlay JY. Pulmonary Hypertension and Mortality in Patients Awaiting Kidney Transplant: Cause for Concern and Potential Opportunity. Transplantation. 2020 10; 104(10):2001-2002.
Khorashadi M, Bokoch MP, Legrand M. Is nitric oxide the forgotten nephroprotective treatment during cardiac surgery? Ann Intensive Care. 2020 Feb 12; 10(1):22.
Efune GE, Zerillo J, Zhou G, Mazzeffi MA, Demaria S, Wang C, Society for the Advancement of Transplant Anesthesia Research Committee Writing Group. Intravenous Fluid Management Practices in Kidney Transplant Patients: A Multicenter Observational Cohort Pilot Study. Semin Cardiothorac Vasc Anesth. 2020 Sep; 24(3):256-264.
House LM, Yen A, Bokoch MP. Central Venous Catheter in the Internal Mammary Vein. Anesthesiology. 2019 Aug; 131(2):397.
Vanessa G. Henke, Michael P. Bokoch, Linda L. Liu. Management of Hyponatremia in End-Stage Liver Disease. Critical Care for Potential Liver Transplant Candidates. 2019 Jan 1; 69-88.
Bokoch MP, Jo H, Valcourt JR, Srinivasan Y, Pan AC, Capponi S, Grabe M, Dror RO, Shaw DE, DeGrado WF, Coughlin SR. Entry from the Lipid Bilayer: A Possible Pathway for Inhibition of a Peptide G Protein-Coupled Receptor by a Lipophilic Small Molecule. Biochemistry. 2018 10 02; 57(39):5748-5758.
Brinson EL, Yu JS, Liu LL, Bokoch MP. Desmopressin Reverses Overly Rapid Serum Sodium Correction in a Hyponatremic Patient Undergoing Living Donor Liver Transplantation: A Case Report. A A Pract. 2018 Aug 01; 11(3):82-84.
Behrends M, Larson MD, Neice AE, Bokoch MP. Suppression of pupillary unrest by general anesthesia and propofol sedation. J Clin Monit Comput. 2019 Apr; 33(2):317-323.
Stephen J Wilson, Kate L Lowe, Michael P Bokoch, Yoga Srinivasan, Roland S Wu, Shaun R Coughlin. Abstract 437: Endothelial Cell Gene Expression in Hypertensive Mice. Arteriosclerosis Thrombosis and Vascular Biology. 2017 May 1; 37(suppl_1).
Bokoch MP, Hiramoto JS, Lobo EP, Shalabi A. Rapid Ventricular Pacing for Landing Zone Precision During Thoracic Endovascular Aortic Arch Repair: A Case Series. J Cardiothorac Vasc Anesth. 2017 12; 31(6):2141-2146.
Neice AE, Behrends M, Bokoch MP, Seligman KM, Conrad NM, Larson MD. Prediction of Opioid Analgesic Efficacy by Measurement of Pupillary Unrest. Anesth Analg. 2017 03; 124(3):915-921.
Bokoch MP, Behrends M, Neice A, Larson MD. Fentanyl, an agonist at the mu opioid receptor, depresses pupillary unrest. Auton Neurosci. 2015 May; 189:68-74.
Michael P. Bokoch, Hyunil I. Jo, James R. Valcourt, Yoga Srinivasan, Kazuma Yasuhara, Albert C. Pan, Ron O. Dror, David E. Shaw, William F. DeGrado, Shaun R. Coughlin. Entry from the Lipid Bilayer: A Novel Pathway for Inhibition of a Peptide G-Protein Coupled Receptor by a Lipophilic Small Molecule. Biophysical Journal. 2015 Jan 1; 108(2):350a.
Bokoch MP, Gelb AW. From the journal archives: cyclopropane: induction and recovery with a bang! Can J Anaesth. 2014 Aug; 61(8):763-6.
Nygaard R, Zou Y, Dror RO, Mildorf TJ, Arlow DH, Manglik A, Pan AC, Liu CW, Fung JJ, Bokoch MP, Thian FS, Kobilka TS, Shaw DE, Mueller L, Prosser RS, Kobilka BK. The dynamic process of β(2)-adrenergic receptor activation. Cell. 2013 Jan 31; 152(3):532-42.
Larda ST, Bokoch MP, Evanics F, Prosser RS. Lysine methylation strategies for characterizing protein conformations by NMR. J Biomol NMR. 2012 Oct; 54(2):199-209.
Bokoch MP, Zou Y, Rasmussen SG, Liu CW, Nygaard R, Rosenbaum DM, Fung JJ, Choi HJ, Thian FS, Kobilka TS, Puglisi JD, Weis WI, Pardo L, Prosser RS, Mueller L, Kobilka BK. Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor. Nature. 2010 Jan 07; 463(7277):108-12.
Michael P. Bokoch, Rie Nygaard, Yaozhong Zou, Soren G.F. Rasmussen, Leonardo Pardo, R. Scott Prosser, Luciano Mueller, Brian K. Kobilka. Conformational Changes in GPCR Surface and Core Probed by [13C]-Methyl NMR Spectroscopy. Biophysical Journal. 2010 Jan 1; 98(3):418a.
Granier S, Kim S, Fung JJ, Bokoch MP, Parnot C. FRET-based measurement of GPCR conformational changes. Methods Mol Biol. 2009; 552:253-68.
Whorton MR, Bokoch MP, Rasmussen SG, Huang B, Zare RN, Kobilka B, Sunahara RK. A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein. Proc Natl Acad Sci U S A. 2007 May 01; 104(18):7682-7.
Perroud TD, Bokoch MP, Zare RN. Cytochrome c conformations resolved by the photon counting histogram: watching the alkaline transition with single-molecule sensitivity. Proc Natl Acad Sci U S A. 2005 Dec 06; 102(49):17570-5.
Michael P Bokoch, Anando Devadoss, Mariela S Palencsár, James D Burgess. Steady-state oxidation of cholesterol catalyzed by cholesterol oxidase in lipid bilayer membranes on platinum electrodes. Analytica Chimica Acta. 2004 Aug 1; 519(1):47-55.
Honors and Awards: 
William K. Hamilton Award for Excellence in Resident Teaching, UCSF, 2019-2020
Jeffrey A. Katz Award, for work ethic and professionalism in patient care, UCSF, 2015
Excellence in Medical Student Teaching Award, UCSF, 2013
Allen B. Barbour Award, Excellence in Clinical Medicine, Stanford University, 2011
Daniel Burke Prize, Excellence in both Biology and Chemistry, Case Western Reserve University, 2003
John Schoff Millis Award, Senior with the best academic record, Case Western Reserve University, 2003
Mateescu Student Citizenship Award, Dept. of Chemistry, Case Western Reserve University, 2003
Phi Beta Kappa, Alpha of Ohio Chapter, Case Western Reserve University, 2003
Olin Freeman Tower Prize, Excellence in Physical Chemistry, Case Western Reserve University, 2002
Merck Index Award, Excellence in Chemistry, Case Western Reserve University, 2001
Trustees' Scholarship, Case Western Reserve University, 1999-2003