Michael Bokoch, MD, PhD

Assoc Professor of Anesthesia
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Publications: 
Marcus, SG
Syed, S
Anderson, AL
Bokoch, MP. Current Anesthesiology Reports. Goal-Directed Therapy in Liver Surgery. 2024; 1-12.
Krone S, Bokoch MP, Kothari R, Fong N, Tallarico RT, Sturgess-DaPrato J, Pirracchio R, Zarbock A, Legrand M. Association between peripheral perfusion index and postoperative acute kidney injury in major noncardiac surgery patients receiving continuous vasopressors: a post hoc exploratory analysis of the VEGA-1 trial. Br J Anaesth. 2024 Apr; 132(4):685-694.
Chen VJ, Guan LS, Bokoch MP, Langnas E, Kothari R, Croci R, Campbell LJ, Quan D, Freise C, Guan Z. Mismatched Postsurgical Opioid Prescription to Liver Transplant Patients: A Retrospective Cohort Study From a Single High-volume Transplant Center. Transplantation. 2024 Feb 01; 108(2):483-490.
Bokoch MP, Tran AT, Brinson EL, Marcus SG, Reddy M, Sun E, Roll GR, Pardo M, Fields S, Adelmann D, Kothari RP, Legrand M. Angiotensin II in liver transplantation (AngLT-1): protocol of a randomised, double-blind, placebo-controlled trial. BMJ Open. 2023 11 19; 13(11):e078713.
Galli AM, Kothari R, Adelmann D, Holm Z, Bokoch MP, De Gasperi A, Niemann CU, Kolodzie K. Lactate concentration at the end of liver transplant: Early predictor of graft function or just one piece of the puzzle? Clin Transplant. 2023 10; 37(10):e15057.
Dixon W, Sheetz K, Adelmann D, Bokoch M, Reddy M, Kothari R, Roberts JP, Syed S, Feng S, Roll G. Real-world implementation of normothermic machine perfusion: A detailed analysis of intraoperative and early postoperative impact. Clin Transplant. 2023 10; 37(10):e15049.
Mavrothalassitis O, Marcus SG, Roll GR, Tallarico RT, Bokoch MP. Pulmonary Injury Causing a Massive Air Leak During Liver Transplantation: A Case Report and Discussion of Decision-Making. A A Pract. 2023 Jun 01; 17(6):e01694.
Legrand M, Kothari R, Fong N, Palaniappa N, Boldt D, Chen LL, Kurien P, Gabel E, Sturgess-DaPrato J, Harhay MO, Pirracchio R, Bokoch MP, VEGA-1 trial investigators. Norepinephrine versus phenylephrine for treating hypotension during general anaesthesia in adult patients undergoing major noncardiac surgery: a multicentre, open-label, cluster-randomised, crossover, feasibility, and pilot trial. Br J Anaesth. 2023 05; 130(5):519-527.
Lazzareschi DV, Fong N, Mavrothalassitis O, Whitlock EL, Chen CL, Chiu C, Adelmann D, Bokoch MP, Chen LL, Liu KD, Pirracchio R, Mathis MR, Legrand M, MPOG Collaborators. Intraoperative Use of Albumin in Major Noncardiac Surgery: Incidence, Variability, and Association With Outcomes. Ann Surg. 2023 10 01; 278(4):e745-e753.
Holland M, Su P, Piper M, Withers J, Harbell MW, Bokoch MP, Sbitany H. Prepectoral Breast Reconstruction Reduces Opioid Consumption and Pain After Mastectomy: A Head-to-Head Comparison With Submuscular Reconstruction. Ann Plast Surg. 2022 11 01; 89(5):492-499.
Legrand M, Bagshaw SM, Koyner JL, Schulman IH, Mathis MR, Bernholz J, Coca S, Gallagher M, Gaudry S, Liu KD, Mehta RL, Pirracchio R, Ryan A, Steubl D, Stockbridge N, Erlandsson F, Turan A, Wilson FP, Zarbock A, Bokoch MP, Casey JD, Rossignol P, Harhay MO. Optimizing the Design and Analysis of Future AKI Trials. J Am Soc Nephrol. 2022 08; 33(8):1459-1470.
Legrand M, Bokoch MP. The Yin and Yang of the Renin-Angiotensin-Aldosterone System in Acute Kidney Injury. Am J Respir Crit Care Med. 2021 05 01; 203(9):1053-1055.
Hannon V, Kothari RP, Zhang L, Bokoch MP, Hill R, Roll GR, Mello A, Feiner JR, Liu KD, Niemann CU, Adelmann D. The Association Between Vena Cava Implantation Technique and Acute Kidney Injury After Liver Transplantation. Transplantation. 2020 11; 104(11):e308-e316.
Bokoch MP, Findlay JY. Pulmonary Hypertension and Mortality in Patients Awaiting Kidney Transplant: Cause for Concern and Potential Opportunity. Transplantation. 2020 10; 104(10):2001-2002.
Khorashadi M, Bokoch MP, Legrand M. Is nitric oxide the forgotten nephroprotective treatment during cardiac surgery? Ann Intensive Care. 2020 Feb 12; 10(1):22.
Efune GE, Zerillo J, Zhou G, Mazzeffi MA, Demaria S, Wang C, Society for the Advancement of Transplant Anesthesia Research Committee Writing Group. Intravenous Fluid Management Practices in Kidney Transplant Patients: A Multicenter Observational Cohort Pilot Study. Semin Cardiothorac Vasc Anesth. 2020 Sep; 24(3):256-264.
House LM, Yen A, Bokoch MP. Central Venous Catheter in the Internal Mammary Vein. Anesthesiology. 2019 Aug; 131(2):397.
Vanessa G. Henke, Michael P. Bokoch, Linda L. Liu. Management of Hyponatremia in End-Stage Liver Disease. Critical Care for Potential Liver Transplant Candidates. 2019 Jan 1; 69-88.
Bokoch MP, Jo H, Valcourt JR, Srinivasan Y, Pan AC, Capponi S, Grabe M, Dror RO, Shaw DE, DeGrado WF, Coughlin SR. Entry from the Lipid Bilayer: A Possible Pathway for Inhibition of a Peptide G Protein-Coupled Receptor by a Lipophilic Small Molecule. Biochemistry. 2018 10 02; 57(39):5748-5758.
Brinson EL, Yu JS, Liu LL, Bokoch MP. Desmopressin Reverses Overly Rapid Serum Sodium Correction in a Hyponatremic Patient Undergoing Living Donor Liver Transplantation: A Case Report. A A Pract. 2018 Aug 01; 11(3):82-84.
Behrends M, Larson MD, Neice AE, Bokoch MP. Suppression of pupillary unrest by general anesthesia and propofol sedation. J Clin Monit Comput. 2019 Apr; 33(2):317-323.
Bokoch MP, Hiramoto JS, Lobo EP, Shalabi A. Rapid Ventricular Pacing for Landing Zone Precision During Thoracic Endovascular Aortic Arch Repair: A Case Series. J Cardiothorac Vasc Anesth. 2017 12; 31(6):2141-2146.
Neice AE, Behrends M, Bokoch MP, Seligman KM, Conrad NM, Larson MD. Prediction of Opioid Analgesic Efficacy by Measurement of Pupillary Unrest. Anesth Analg. 2017 03; 124(3):915-921.
Bokoch MP, Behrends M, Neice A, Larson MD. Fentanyl, an agonist at the mu opioid receptor, depresses pupillary unrest. Auton Neurosci. 2015 May; 189:68-74.
Bokoch MP, Gelb AW. From the journal archives: cyclopropane: induction and recovery with a bang! Can J Anaesth. 2014 Aug; 61(8):763-6.
Nygaard R, Zou Y, Dror RO, Mildorf TJ, Arlow DH, Manglik A, Pan AC, Liu CW, Fung JJ, Bokoch MP, Thian FS, Kobilka TS, Shaw DE, Mueller L, Prosser RS, Kobilka BK. The dynamic process of β(2)-adrenergic receptor activation. Cell. 2013 Jan 31; 152(3):532-42.
Larda ST, Bokoch MP, Evanics F, Prosser RS. Lysine methylation strategies for characterizing protein conformations by NMR. J Biomol NMR. 2012 Oct; 54(2):199-209.
Bokoch MP, Zou Y, Rasmussen SG, Liu CW, Nygaard R, Rosenbaum DM, Fung JJ, Choi HJ, Thian FS, Kobilka TS, Puglisi JD, Weis WI, Pardo L, Prosser RS, Mueller L, Kobilka BK. Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor. Nature. 2010 Jan 07; 463(7277):108-12.
Granier S, Kim S, Fung JJ, Bokoch MP, Parnot C. FRET-based measurement of GPCR conformational changes. Methods Mol Biol. 2009; 552:253-68.
Whorton MR, Bokoch MP, Rasmussen SG, Huang B, Zare RN, Kobilka B, Sunahara RK. A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein. Proc Natl Acad Sci U S A. 2007 May 01; 104(18):7682-7.
Perroud TD, Bokoch MP, Zare RN. Cytochrome c conformations resolved by the photon counting histogram: watching the alkaline transition with single-molecule sensitivity. Proc Natl Acad Sci U S A. 2005 Dec 06; 102(49):17570-5.
Michael P Bokoch, Anando Devadoss, Mariela S Palencsár, James D Burgess. Steady-state oxidation of cholesterol catalyzed by cholesterol oxidase in lipid bilayer membranes on platinum electrodes. Analytica Chimica Acta. 2004 Aug 1; 519(1):47-55.
Honors and Awards: 
Short-Term Mentor Award (Summer Explore program), UCSF, 2023
William K. Hamilton Award for Excellence in Resident Teaching, UCSF Anesthesia, 2023
William K. Hamilton Award for Excellence in Resident Teaching, UCSF Anesthesia, 2020
William K. Hamilton Award for Excellence in Resident Teaching, UCSF Anesthesia, 2019
Jeffrey A. Katz Award, for work ethic and professionalism in patient care, UCSF Anesthesia, 2015
Excellence in Medical Student Teaching Award, UCSF, 2013
Allen B. Barbour Award, Excellence in Clinical Medicine, Stanford University, 2011
Daniel Burke Prize, Excellence in both Biology and Chemistry, Case Western Reserve University, 2003
John Schoff Millis Award, Senior with the best academic record, Case Western Reserve University, 2003
Mateescu Student Citizenship Award, Dept. of Chemistry, Case Western Reserve University, 2003
Phi Beta Kappa, Alpha of Ohio Chapter, Case Western Reserve University, 2003
Olin Freeman Tower Prize, Excellence in Physical Chemistry, Case Western Reserve University, 2002
Merck Index Award, Excellence in Chemistry, Case Western Reserve University, 2001
Trustees' Scholarship, Case Western Reserve University, 1999-2003