Role Faculty Category Clinical Education 1965 - , University of Kansas Publications Response to Letter to the Editor for: "The Pupillary Light-Off Reflex in Acute Disorders of Consciousness". Kondziella D, Stückler SG, Larson MD Neurocritical care . Jul 8, 2025 Cortical, subcortical, brainstem and autonomic responses to nociception under total intravenous anesthesia. Vide S, Kreuzer M, Ferreira A, Couto M, Agustí M, Jaramillo S, Schneider G, García PS, Abelha F, Amorim P, Trocóniz I, Larson M, Gambús P Journal of clinical anesthesia . Apr 12, 2025 The Pupillary Light-Off Reflex in Acute Disorders of Consciousness. Zarifkar P, Othman MH, Hansen KIT, Amiri M, Stückler SG, Fabritius ML, Sigurdsson ST, Hassager C, Birkeland PF, Hauerberg J, Møller K, Kjaergaard J, Larson MD, Kondziella D Neurocritical care . Sep 25, 2024 Population study of pupillary unrest in ambient light. McKay RE, Kohn M, Schwartz E, Larson MD Autonomic neuroscience : basic & clinical . Jul 3, 2024 Absence of pupillary reflex dilation in response to a laryngeal test stimulus may predict safe tracheal extubation in anesthetized children. Abelson D, Larson MD Paediatric anaesthesia . Jun 22, 2024 Measurements of pupillary unrest using infrared pupillometry fail to detect changes in pain intensity in patients after surgery: a prospective observational study. Behrends M, Larson MD Canadian journal of anaesthesia = Journal canadien d'anesthesie . Mar 19, 2024 Overcoming Obstacles: The Legacy of Fidel Pagés, Founder of the Epidural, 100 Years After His Passing. Chinn GA, Gray AT, Larson MD Anesthesia and analgesia . Dec 4, 2023 Commentary on pupillometry and pain ratings. Larson MD European journal of pain (London, England) . Jul 9, 2023 Brimonidine eye drops reveal diminished sympathetic pupillary tone in comatose patients with brain injury. Jakobsen EW, Nersesjan V, Albrechtsen SS, Othman MH, Amiri M, Knudsen NV, Larson MD, Hassager C, Møller K, Kjaergaard J, Kondziella D Acta neurochirurgica . Apr 4, 2023 Reader Response: Automated Quantitative Pupillometry in the Critically Ill: A Systematic Review of the Literature. Larson MD Neurology . Dec 14, 2021 Semimechanistic models to relate noxious stimulation, movement, and pupillary dilation responses in the presence of opioids. Marco-Ariño N, Vide S, Agustí M, Chen A, Jaramillo S, Irurzun-Arana I, Pacheco A, Gonzalez C, Jensen EW, Capsi-Morales P, Valencia JF, Troconiz IF, Gambus PL, Larson MD CPT: pharmacometrics & systems pharmacology . Nov 18, 2021 Detection of Opioid Effect with Pupillometry McKay, Rachel Eshima Larson, Merlin D. Autonomic Neuroscience . Sep 18, 2021 Monitoring the Depth of Palliative Sedation by Video-Pupillometry: A Case Report. Palliative Medicine Elyn, A Saffon, N Larson, M Monitoring the Depth of Palliative Sedation by Video-Pupillometry: A Case Report. Palliative Medicine . Sep 18, 2021 Reader Response: Automated Quantitative Pupillometry in the Critically Ill. Neurology Larson, M Reader Response: Automated Quantitative Pupillometry in the Critically Ill. Neurology . Sep 18, 2021 Monitoring the depth of palliative sedation by video-pupillometry: A case report. Elyn A, Saffon N, Larson M Palliative medicine . Sep 2, 2021 Detection of opioid effect with pupillometry. McKay RE, Larson MD Autonomic neuroscience : basic & clinical . Aug 18, 2021 Pupillary unrest, opioid intensity, and the impact of environmental stimulation on respiratory depression. McKay RE, Kohn MA, Larson MD Journal of clinical monitoring and computing . Mar 2, 2021 Evaluation of two portable pupillometers to assess clinical utility. McKay RE, Kohn MA, Schwartz ES, Larson MD Concussion (London, England) . Oct 28, 2020 Nociceptive monitor subtypes. Comment on 'Objective monitoring of nociception: a review of current commercial solutions' (Br J Anaesth 2019; 123:e312-e321). Larson M, Neice A British journal of anaesthesia . Jul 29, 2019 Pharmacodynamic modelling of the effect of remifentanil using the Pupillary Pain Index. Vide S, Castro A, Antunes P, Lima D, Larson M, Gambús P, Amorim P Journal of clinical monitoring and computing . May 22, 2019 Suppression of pupillary unrest by general anesthesia and propofol sedation. Behrends M, Larson MD, Neice AE, Bokoch MP Journal of clinical monitoring and computing . May 21, 2018 Pupillary Unrest in Ambient Light and Prediction of Opioid Responsiveness: Case Report on Its Utility in the Management of 2 Patients With Challenging Acute Pain Conditions. McKay RE, Neice AE, Larson MD A&A practice . May 15, 2018 In Response. Neice AE, Larson MD, Behrends M, Bokoch MP Anesthesia and analgesia . Aug 1, 2017 Prediction of Opioid Analgesic Efficacy by Measurement of Pupillary Unrest. Neice AE, Behrends M, Bokoch MP, Seligman KM, Conrad NM, Larson MD Anesthesia and analgesia . Mar 1, 2017 Portable infrared pupillometry in critical care. Larson MD, Singh V Critical care (London, England) . Jun 22, 2016 Portable infrared pupillometry: a review. Larson MD, Behrends M Anesthesia and analgesia . Jun 1, 2015 Pupillary Reflex Dilation to Predict Movement: A Step Forward Toward Real-time Individualized Intravenous Anesthetics. Larson MD, Gupta DK Anesthesiology . May 1, 2015 Fentanyl, an agonist at the mu opioid receptor, depresses pupillary unrest. Bokoch MP, Behrends M, Neice A, Larson MD Autonomic neuroscience : basic & clinical . Feb 18, 2015 Pupillary effects of high-dose opioid quantified with infrared pupillometry. Rollins MD, Feiner JR, Lee JM, Shah S, Larson M Anesthesiology . Nov 1, 2014 Infrared pupillometry to detect the light reflex during cardiopulmonary resuscitation: a case series. Behrends M, Niemann CU, Larson MD Resuscitation . May 30, 2012 Pupillometry to guide postoperative analgesia. Larson MD, Sessler DI Anesthesiology . May 1, 2012 Procedure-specific guidelines. Stites-Hallett N, Larson MD Anesthesiology . Aug 1, 2010 The effect of ketamine and nitrous oxide on the human pupillary light reflex during general anesthesia. Eilers H, Larson MD Autonomic neuroscience : basic & clinical . Nov 11, 2009 Mechanism of opioid-induced pupillary effects. Larson MD Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology . Apr 7, 2008 Efficacy of epidural block during general anesthesia. Larson MD, Fung RS, Infosino AJ, Baba A Anesthesiology . Sep 1, 2006 Induction rooms. Larson MD, Senturk M Bulletin of anesthesia history . Apr 1, 2006 Evaluation of the portable infrared pupillometer. Du R, Meeker M, Bacchetti P, Larson MD, Holland MC, Manley GT Neurosurgery . Jul 1, 2005 Tolerance to miotic effects of opioids. Kollars JP, Larson MD Anesthesiology . Mar 1, 2005 Pupil examination: validity and clinical utility of an automated pupillometer. Meeker M, Du R, Bacchetti P, Privitera CM, Larson MD, Holland MC, Manley G The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses . Feb 1, 2005 Latency of pupillary reflex dilation during general anesthesia. Larson MD, Berry PD, May J, Bjorksten A, Sessler DI Journal of applied physiology (Bethesda, Md. : 1985) . Aug 1, 2004 Mechanism of pupillary reflex dilation in awake volunteers and in organ donors. Yang LL, Niemann CU, Larson MD Anesthesiology . Dec 1, 2003 The effect of antiemetics on pupillary reflex dilation during epidural/general anesthesia. Larson MD Anesthesia and analgesia . Dec 1, 2003 Effect of asphyxia on the pupils of brain dead subjects. Larson MD, May J Resuscitation . Oct 1, 2002 Infrared pupillometry during uncal herniation. Manley GT, Larson MD Journal of neurosurgical anesthesiology . Jul 1, 2002 The effect of opioids on thermoregulatory responses in humans and the special antishivering action of meperidine. Ikeda T, Kurz A, Sessler DI, Go J, Kurz M, Belani K, Larson M, Bjorksten AR, Dechert M, Christensen R Annals of the New York Academy of Sciences . Mar 15, 1997 Alteration of Human Pupillary Light Reflex by General Anesthesia Larson, Merlin D. Anesthesiology Review . Jan 1, 1989 Anaesthesia Larson, Merlin D. Miotic effects of Opioids . Jan 1, 1987 Pupillary Effects of General Anesthesia Larson, Merlin D. Anesthesiology Review . Jan 1, 1985