Lee-Lynn Chen, MD

HS Clinical Professor
Biography: 

Dr. Lee-lynn Chen is an anesthesiologist who cares for patients before and during surgery, as well as for those in the intensive care unit. He also cares for patients with complicated, chronic medical, surgical or neurological pain.

Chen's research focuses on raising the quality of pain management, in the areas of both patient care and education. Working with various departments across UCSF, he is a leader in promoting enhanced recovery after surgery – a multidisciplinary effort to improve surgical outcomes and enhance patients' experiences. He is also passionate about the education of medical students and residents, with a particular interest in how using simulation-based courses can improve anesthesia education.

Chen earned his medical degree at the University of Rochester. He completed a residency in anesthesia at UCSF, where he also completed a fellowship in critical care medicine.

Chen is a member of the American Society of Anesthesiologists, California Society of Anesthesiologists, International Anesthesia Research Society, Society for Simulation in Healthcare, Association of University Anesthesiologists and American Society for Enhanced Recovery.

Publications: 
McNamara B, Guerra R, Qin J, Craig AD, Chen LM, Varma MG, Chapman JS. Survival impact of bowel resection at the time of interval cytoreductive surgery for advanced ovarian cancer. Gynecol Oncol Rep. 2021 Nov; 38:100870.
Pozzar RA, Hammer MJ, Cooper BA, Kober KM, Chen LM, Paul SM, Conley YP, Cartwright F, Wright F, Levine JD, Miaskowski C. Stability of Symptom Clusters in Patients With Gynecologic Cancer Receiving Chemotherapy. Cancer Nurs. 2022 Jul-Aug 01; 45(4):E706-E718.
Craig AD, Garcia E, Peters PN, Chen LM, Chapman JS. Primary treatment of advanced ovarian cancer: how does the 'real world' practice? Future Oncol. 2021 Dec; 17(34):4687-4696.
McNally L, Rabban JT, Poder L, Chetty S, Ueda S, Chen LM. Differentiating complete hydatidiform mole and coexistent fetus and placental mesenchymal dysplasia: A series of 9 cases and review of the literature. Gynecol Oncol Rep. 2021 Aug; 37:100811.
Swanson M, Nakalembe M, Chen LM, Ueda S, Namugga J, Nakisige C, Huchko MJ. Surgical candidacy and treatment initiation among women with cervical cancer at public referral hospitals in Kampala, Uganda: a descriptive cohort study. BMJ Open. 2020 12 12; 10(12):e039946.
Atallah M, Cooper B, Muñoz RF, Paul SM, Anguera J, Levine JD, Hammer M, Wright F, Chen LM, Melisko M, Conley YP, Miaskowski C, Dunn LB. Psychological Symptoms and Stress Are Associated With Decrements in Attentional Function in Cancer Patients Undergoing Chemotherapy. Cancer Nurs. 2020 Sep/Oct; 43(5):402-410.
Sinha S, Lazar A, Lam A, Anderson EM, Chen LM, Hsu IJ, Yoshida EJ. Adjuvant radiation followed by chemotherapy is associated with improved overall survival in endometrial cancer. Gynecol Oncol. 2020 10; 159(1):30-35.
Sarin A, Lancaster E, Chen LL, Porten S, Chen LM, Lager J, Wick E. Using provider-focused education toolkits can aid enhanced recovery programs to further reduce patient exposure to opioids. Perioper Med (Lond). 2020; 9:21.
Peters PN, Pierson WE, Chen LM, Westphalen AC, Chapman JS, Hsu IC. PET-detected asymptomatic recurrence is associated with improved survival in recurrent cervical cancer. Abdom Radiol (NY). 2021 01; 46(1):341-350.
McNally L, Zhou Y, Robinson JF, Zhao G, Chen LM, Chen H, Kim MY, Kapidzic M, Gormley M, Hannibal R, Fisher SJ. Up-regulated cytotrophoblast DOCK4 contributes to over-invasion in placenta accreta spectrum. Proc Natl Acad Sci U S A. 2020 07 07; 117(27):15852-15861.
Pierson WE, Peters PN, Chang MT, Chen LM, Quigley DA, Ashworth A, Chapman JS. An integrated molecular profile of endometrioid ovarian cancer. Gynecol Oncol. 2020 04; 157(1):55-61.
Chen LM, Blank SV, Burton E, Glass K, Penick E, Woodard T. Corrigendum to "Reproductive and hormonal considerations in women at increased risk for hereditary gynecologic cancers: Society of Gynecologic Oncology and American Society for reproductive medicine evidence-based review" [Gynecol. Oncol. 155 (2019) 508-514]. Gynecol Oncol. 2020 Mar; 156(3):748.
Chen LM, Blank SV, Burton E, Glass K, Penick E, Woodard T. Reproductive and Hormonal Considerations in Women at Increased Risk for Hereditary Gynecologic Cancers: Society of Gynecologic Oncology and American Society for Reproductive Medicine Evidence-Based Review. Gynecol Oncol. 2019 12; 155(3):508-514.
Chen LM, Blank SV, Burton E, Glass K, Penick E, Woodard T. Reproductive and hormonal considerations in women at increased risk for hereditary gynecologic cancers: Society of Gynecologic Oncology and American Society for Reproductive Medicine Evidence-Based Review. Fertil Steril. 2019 12; 112(6):1034-1042.
Ahmad TR, Chen LM, Chapman JS, Chen LL. Medicaid and Medicare payer status are associated with worse surgical outcomes in gynecologic oncology. Gynecol Oncol. 2019 10; 155(1):93-97.
Holschneider CH, Petereit DG, Chu C, Hsu IC, Ioffe YJ, Klopp AH, Pothuri B, Chen LM, Yashar C. Brachytherapy: A critical component of primary radiation therapy for cervical cancer: From the Society of Gynecologic Oncology (SGO) and the American Brachytherapy Society (ABS). Gynecol Oncol. 2019 03; 152(3):540-547.
Sethi R, Mayadev J, Sethi S, Rash D, Chen LM, Brooks R, Ueda S, Hsu IC. Patterns of Recurrence in Node-Positive Cervical Cancer Patients Treated With Contemporary Chemoradiation and Dose Escalation: A Multi-Institutional Study. Pract Radiat Oncol. 2019 Mar; 9(2):e180-e186.
Manrriquez E, Chapman JS, Mak J, Blanco AM, Chen LM. Disparities in genetics assessment for women with ovarian cancer: Can we do better? Gynecol Oncol. 2018 04; 149(1):84-88.
Liao CI, Chow S, Chen LM, Kapp DS, Mann A, Chan JK. Trends in the incidence of serous fallopian tube, ovarian, and peritoneal cancer in the US. Gynecol Oncol. 2018 05; 149(2):318-323.
Swanson M, Ueda S, Chen LM, Huchko MJ, Nakisige C, Namugga J. Evidence-based improvisation: Facing the challenges of cervical cancer care in Uganda. Gynecol Oncol Rep. 2018 May; 24:30-35.
Sarin A, Chen LL, Wick EC. Enhanced recovery after surgery-Preoperative fasting and glucose loading-A review. J Surg Oncol. 2017 Oct; 116(5):578-582.
Ohliger MA, Hope TA, Chapman JS, Chen LM, Behr SC, Poder L. PET/MR Imaging in Gynecologic Oncology. Magn Reson Imaging Clin N Am. 2017 Aug; 25(3):667-684.
Portillas R, Turner B, Jeffers A, Chen LL, Champagne M. High-Dose Interleukin-2: Evaluation of a Standardized Order Set for Biotherapy in an Intensive Care Unit
. Clin J Oncol Nurs. 2017 Apr 01; 21(2):E49-E53.
Salani R, Khanna N, Frimer M, Bristow RE, Chen LM. An update on post-treatment surveillance and diagnosis of recurrence in women with gynecologic malignancies: Society of Gynecologic Oncology (SGO) recommendations. Gynecol Oncol. 2017 07; 146(1):3-10.
Hay CM, Lefkowits C, Crowley-Matoka M, Bakitas MA, Clark LH, Duska LR, Urban RR, Chen LM, Creasy SL, Schenker Y. Gynecologic Oncologist Views Influencing Referral to Outpatient Specialty Palliative Care. Int J Gynecol Cancer. 2017 03; 27(3):588-596.
Chen LM, Chen LL, Chapman JS. In Reply. Obstet Gynecol. 2017 01; 129(1):208.
Westhoff GL, Fuh KC, Longacre TA, McNally JL, Hsu IC, Kapp DS, Teng N, Chen LM. Radiation Therapy for Recurrent Clear-Cell Cancer of the Ovary. Int J Gynecol Cancer. 2016 11; 26(9):1608-1614.
Chen LM. STIC-ing with what we know. Gynecol Oncol. 2016 11; 143(2):227-228.
The International Surgical Outcomes Study Group. . Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries. British Journal Of Anaesthesia. 2016; 5(117):601-9.
Sarin A, Litonius ES, Naidu R, Yost CS, Varma MG, Chen LL. Successful implementation of an Enhanced Recovery After Surgery program shortens length of stay and improves postoperative pain, and bowel and bladder function after colorectal surgery. BMC Anesthesiol. 2016 08 03; 16(1):55.
Chan JL, Letourneau J, Salem W, Cil AP, Chan SW, Chen LM, Rosen MP. Regret around fertility choices is decreased with pre-treatment counseling in gynecologic cancer patients. J Cancer Surviv. 2017 02; 11(1):58-63.
Chapman JS, Roddy E, Ueda S, Brooks R, Chen LL, Chen LM. Enhanced Recovery Pathways for Improving Outcomes After Minimally Invasive Gynecologic Oncology Surgery. Obstet Gynecol. 2016 07; 128(1):138-144.
Whitlock EL, Feiner JR, Chen LL. In Reply. Anesthesiology. 2016 06; 124(6):1419.
Whitlock EL, Feiner JR, Chen LL. Perioperative Mortality, 2010 to 2014: A Retrospective Cohort Study Using the National Anesthesia Clinical Outcomes Registry. Anesthesiology. 2015 Dec; 123(6):1312-21.
Letourneau J, Chan J, Salem W, Chan SW, Shah M, Ebbel E, McCulloch C, Chen LM, Cedars M, Rosen M. Fertility Sparing Surgery for Localized Ovarian Cancers Maintains an Ability to Conceive, but is Associated With Diminished Reproductive Potential. J Surg Oncol. 2015 Jul; 112(1):26-30.
Landrum LM, Blank S, Chen LM, Duska L, Bae-Jump V, Lee PS, Levine L, McCourt C, Moore KN, Urban RR. Comprehensive care in gynecologic oncology: The importance of palliative care. Gynecol Oncol. 2015 May; 137(2):193-202.
Cohn B, Chen LL. Central line-associated blood stream infections and ventilator-associated events in the intensive care unit (ICU). 2013; ICU Director: 4(6): 310-316.. Central line-associated blood stream infections and ventilator-associated events in the intensive care unit (ICU). ICU Director. 2013; 6(4):310-316.
Ruskin R, Urban RR, Sherman AE, Chen LL, Powell CB, Burkhardt DH, Chen LM. Predictors of intensive care unit utilization in gynecologic oncology surgery. Int J Gynecol Cancer. 2011 Nov; 21(8):1336-42.
Chen LM, Weinberg VK, Chen C, Powell CB, Chen LL, Chan JK, Burkhardt DH. Perioperative outcomes comparing patient controlled epidural versus intravenous analgesia in gynecologic oncology surgery. Gynecol Oncol. 2009 Dec; 115(3):357-61.
Chang WC, Meux MD, Yeh BM, Qayyum A, Joe BN, Chen LM, Coakley FV. CT and MRI of adnexal masses in patients with primary nonovarian malignancy. AJR Am J Roentgenol. 2006 Apr; 186(4):1039-45.
Schmeler KM, Lynch HT, Chen LM, Munsell MF, Soliman PT, Clark MB, Daniels MS, White KG, Boyd-Rogers SG, Conrad PG, Yang KY, Rubin MM, Sun CC, Slomovitz BM, Gershenson DM, Lu KH. Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome. N Engl J Med. 2006 Jan 19; 354(3):261-9.