Role Faculty Category Clinical Publications A mixed (long- and medium-chain) triglyceride lipid emulsion extracts local anesthetic from human serum in vitro more effectively than a long-chain emulsion. Ruan W, French D, Wong A, Drasner K, Wu AH Anesthesiology . Feb 1, 2012 Partition constant and volume of distribution as predictors of clinical efficacy of lipid rescue for toxicological emergencies. French D, Smollin C, Ruan W, Wong A, Drasner K, Wu AH Clinical toxicology (Philadelphia, Pa.) . Oct 7, 2011 Serum verapamil concentrations before and after Intralipid® therapy during treatment of an overdose. French D, Armenian P, Ruan W, Wong A, Drasner K, Olson KR, Wu AH Clinical toxicology (Philadelphia, Pa.) . Apr 1, 2011 Anesthetic effects on the developing nervous system: if you aren't concerned, you haven't been paying attention. Drasner K Anesthesiology . Jul 1, 2010 Safety of ultrasound-guided regional anesthesia. Gray AT, Drasner K Anesthesiology . Jun 1, 2010 ASRA practice advisory on local anesthetic systemic toxicity. Neal JM, Bernards CM, Butterworth JF, Di Gregorio G, Drasner K, Hejtmanek MR, Mulroy MF, Rosenquist RW, Weinberg GL Regional anesthesia and pain medicine . Mar 1, 2010 Local anesthetic systemic toxicity: a historical perspective. Drasner K Regional anesthesia and pain medicine . Mar 1, 2010 Safety of high volume lipid emulsion infusion: a first approximation of LD50 in rats. Hiller DB, Di Gregorio G, Kelly K, Ripper R, Edelman L, Boumendjel R, Drasner K, Weinberg GL Regional anesthesia and pain medicine . Mar 1, 2010 Continuous spinal analgesia for labor and delivery: a born-again technique? Drasner K, Smiley R Anesthesiology . Feb 1, 2008 Epidural chloroprocaine-standard of care for postpartum bilateral tubal ligation. Drasner K Anesthesia and analgesia . Oct 1, 2005 Chloroprocaine spinal anesthesia: back to the future? Drasner K Anesthesia and analgesia . Feb 1, 2005 Thoracic epidural anesthesia: asleep at the wheal? Drasner K Anesthesia and analgesia . Aug 1, 2004 Sodium bisulfite: scapegoat for chloroprocaine neurotoxicity? Taniguchi M, Bollen AW, Drasner K Anesthesiology . Jan 1, 2004 Comparative spinal neurotoxicity of prilocaine and lidocaine. Kishimoto T, Bollen AW, Drasner K Anesthesiology . Nov 1, 2002 Local anesthetic neurotoxicity: clinical injury and strategies that may minimize risk. Drasner K Regional anesthesia and pain medicine . Nov 1, 2002 Epinephrine increases the neurotoxic potential of intrathecally administered lidocaine in the rat. Hashimoto K, Hampl KF, Nakamura Y, Bollen AW, Feiner J, Drasner K Anesthesiology . May 1, 2001 Low concentrations of halothane increase response to a noxious thermal stimulus and attenuate the antinociceptive effect of intraventricular but not intrathecal morphine. Drasner K Anesthesiology . Feb 1, 2001 Comparative toxicity of glucose and lidocaine administered intrathecally in the rat. Hashimoto K, Sakura S, Bollen AW, Ciriales R, Drasner K Regional anesthesia and pain medicine . Sep 1, 1998 Transient neurologic symptoms after spinal anesthesia: an epidemiologic study of 1,863 patients. Freedman JM, Li DK, Drasner K, Jaskela MC, Larsen B, Wi S Anesthesiology . Sep 1, 1998 Lidocaine toxicity in primary afferent neurons from the rat. Gold MS, Reichling DB, Hampl KF, Drasner K, Levine JD The Journal of pharmacology and experimental therapeutics . May 1, 1998 A comparative study of low-dose hyperbaric spinal lidocaine 0.5% versus 5% for continuous spinal anesthesia. Chan VW, Garcia J, Al-Kaisy A, Drasner K Regional anesthesia and pain medicine . Mar 1, 1998 Transient neurologic symptoms after spinal anesthesia: a lower incidence with prilocaine and bupivacaine than with lidocaine. Hampl KF, Heinzmann-Wiedmer S, Luginbuehl I, Harms C, Seeberger M, Schneider MC, Drasner K Anesthesiology . Mar 1, 1998 The addition of phenylephrine contributes to the development of transient neurologic symptoms after spinal anesthesia with 0.5% tetracaine. Sakura S, Sumi M, Sakaguchi Y, Saito Y, Kosaka Y, Drasner K Anesthesiology . Oct 1, 1997 Lidocaine spinal anesthesia: a vanishing therapeutic index? Drasner K Anesthesiology . Sep 1, 1997 A similar incidence of transient neurologic symptoms after spinal anesthesia with 2% and 5% lidocaine. Hampl KF, Schneider MC, Pargger H, Gut J, Drewe J, Drasner K Anesthesia and analgesia . Nov 1, 1996 Intrathecal catheterization in the rat. Improved technique for morphologic analysis of drug-induced injury. Sakura S, Hashimoto K, Bollen AW, Ciriales R, Drasner K Anesthesiology . Nov 1, 1996 Spontaneous intracranial hypotension: a series. Weitz SR, Drasner K Anesthesiology . Oct 1, 1996 [Neurologic sequelae of spinal anesthesia: local anesthetic toxicity]. Sakura S, Drasner K Masui. The Japanese journal of anesthesiology . Jul 1, 1996 Local anesthetic neurotoxicity does not result from blockade of voltage-gated sodium channels. Sakura S, Bollen AW, Ciriales R, Drasner K Anesthesia and analgesia . Aug 1, 1995 Local anesthetic test dose as a predictor of effective epidural opioid analgesia. Weitz SR, Drasner K Anesthesiology . Jul 1, 1995 Effects of perioperative dexmedetomidine infusion in patients undergoing vascular surgery. The Study of Perioperative Ischemia Research Group. Talke P, Li J, Jain U, Leung J, Drasner K, Hollenberg M, Mangano DT Anesthesiology . Mar 1, 1995 The addition of 7.5% glucose does not alter the neurotoxicity of 5% lidocaine administered intrathecally in the rat. Sakura S, Chan VW, Ciriales R, Drasner K Anesthesiology . Jan 1, 1995 Persistent sacral sensory deficit induced by intrathecal local anesthetic infusion in the rat. Drasner K, Sakura S, Chan VW, Bollen AW, Ciriales R Anesthesiology . Apr 1, 1994 Models for local anesthetic toxicity from continuous spinal anesthesia. Drasner K Regional anesthesia . Nov 1, 1993 Cauda equina syndrome following intended epidural anesthesia. Drasner K, Rigler ML, Sessler DI, Stoller ML Anesthesiology . Sep 1, 1992 Distribution of catheter-injected local anesthetic in a model of the subarachnoid space. Rigler ML, Drasner K Anesthesiology . Oct 1, 1991 Lumbar intrathecal morphine alters activity of putative nociceptive modulatory neurons in rostral ventromedial medulla. Heinricher MM, Drasner K Brain research . May 24, 1991 Cauda equina syndrome after continuous spinal anesthesia. Rigler ML, Drasner K, Krejcie TC, Yelich SJ, Scholnick FT, DeFontes J, Bohner D Anesthesia and analgesia . Mar 1, 1991 Hypotension during transfusion of autologous blood. Miller AC, Scherba-Krugliak L, Toy PT, Drasner K Anesthesiology . Mar 1, 1991 Is chronic ethanol consumption associated with tolerance to intrathecal lidocaine in the rat? Fassoulaki A, Drasner K, Eger EI Anesthesia and analgesia . May 1, 1990 Preoperative laboratory testing of children undergoing elective surgery. O'Connor ME, Drasner K Anesthesia and analgesia . Feb 1, 1990 Opioid peptides (DAGO-enkephalin, dynorphin A(1-13), BAM 22P) microinjected into the rat brainstem: comparison of their antinociceptive effect and their effect on neuronal firing in the rostral ventromedial medulla. Fang FG, Haws CM, Drasner K, Williamson A, Fields HL Brain research . Oct 30, 1989 Intrathecal morphine reduces the minimum alveolar concentration of halothane in humans. Drasner K, Bernards CM, Ozanne GM Anesthesiology . Sep 1, 1988 Synergy between the antinociceptive effects of intrathecal clonidine and systemic morphine in the rat. Drasner K, Fields HL Pain . Mar 1, 1988