Biography Kate provides scientific and organizational oversight of the department’s research enterprise and works with faculty leadership to develop, implement, and evaluate initiatives to address faculty and trainee research needs. She is a member of the Research Operations Committee and the administrative director of the Clinical Research Core. Kate writes the monthly Anesthesia Research Digest newsletter and manages the Anesthesia Biostats and Clinical Research Design (ABCD) Group, the department’s T32 training grant, faculty MOUs for research time, and internal research award programs. She supervises a team of staff with diverse expertise in grant writing, clinical trials administration, and research event planning. Kate has a Ph.D. in Chemistry and studied protein interactions at cell membrane interfaces before deciding that she prefers facilitating over doing research. Outside of work, she enjoys hiking, cooking, and practicing yoga. Role Non-Faculty Academic Category Research Education 2019 - Diversity, Equity, and Inclusion Champion Training, University of California, San FranciscoPh.D., 2015 - Chemistry - Biophysical Chemistry, University of California, BerkeleyB.S., 2010 - Chemistry - Biochemistry, Haverford College Publications Membrane Association Transforms an Inert Anti-TCRβ Fab' Ligand into a Potent T Cell Receptor Agonist. Lin JJ, O'Donoghue GP, Wilhelm KB, Coyle MP, Low-Nam ST, Fay NC, Alfieri KN, Groves JT Mapping the stochastic sequence of individual ligand-receptor binding events to cellular activation: T cells act on the rare events. Lin JJY, Low-Nam ST, Alfieri KN, McAffee DB, Fay NC, Groves JT Early T cell receptor signals globally modulate ligand:receptor affinities during antigen discrimination. Pielak RM, O'Donoghue GP, Lin JJ, Alfieri KN, Fay NC, Low-Nam ST, Groves JT Using infrared spectroscopy of cyanylated cysteine to map the membrane binding structure and orientation of the hybrid antimicrobial peptide CM15. Alfieri KN, Vienneau AR, Londergan CH Polyglutamine fibrils are formed using a simple designed beta-hairpin model. Smith MH, Miles TF, Sheehan M, Alfieri KN, Kokona B, Fairman R Cyanylated Cysteine: A Covalently Attached Vibrational Probe of Protein-Lipid Contacts. McMahon HA, Alfieri KN, Clark KA, Londergan CH
