Biography Dr. Kate Alfieri is the Director of Research Development and Training in the Department of Anesthesia and Perioperative Care. She is the primary scientific advisor to the Vice Chair for Research and develops, implements, and evaluates initiatives to address faculty and trainee research needs. Before joining UCSF, Kate was the Scientific Program Manager at the Stanford ChEM-H Institute, where she developed and managed interdisciplinary programs aimed to advance research and training at the interface of chemistry, engineering, and medicine. Kate received her B.S. in Chemistry with a concentration in Biochemistry from Haverford College and her Ph.D. in Chemistry, studying cell signaling at membrane interfaces, in the lab of Dr. Jay T. Groves at UC Berkeley. She is passionate about diversity in STEM, science communication and outreach, and mentorship in science. Role Staff Category Research Education 2019 - Diversity, Equity, and Inclusion Champion Training, University of California, San FranciscoPh.D., 2015 - Chemistry - Biophysical Chemistry, University of California, BerkeleyB.S., 2010 - Chemistry - Biochemistry, Haverford College Publications Membrane Association Transforms an Inert Anti-TCRβ Fab' Ligand into a Potent T Cell Receptor Agonist. Lin JJ, O'Donoghue GP, Wilhelm KB, Coyle MP, Low-Nam ST, Fay NC, Alfieri KN, Groves JT Mapping the stochastic sequence of individual ligand-receptor binding events to cellular activation: T cells act on the rare events. Lin JJY, Low-Nam ST, Alfieri KN, McAffee DB, Fay NC, Groves JT Early T cell receptor signals globally modulate ligand:receptor affinities during antigen discrimination. Pielak RM, O'Donoghue GP, Lin JJ, Alfieri KN, Fay NC, Low-Nam ST, Groves JT Using infrared spectroscopy of cyanylated cysteine to map the membrane binding structure and orientation of the hybrid antimicrobial peptide CM15. Alfieri KN, Vienneau AR, Londergan CH Polyglutamine fibrils are formed using a simple designed beta-hairpin model. Smith MH, Miles TF, Sheehan M, Alfieri KN, Kokona B, Fairman R Cyanylated Cysteine: A Covalently Attached Vibrational Probe of Protein-Lipid Contacts. McMahon HA, Alfieri KN, Clark KA, Londergan CH
