Gregory Chinn, MD, PhD
Asst Professor in Residence
Biography:
Gregory Chinn is a board certified anesthesiologist and research scientist who practices anesthesia at the Zuckerberg San Francisco General Hospital. His research focus is on developmental neurotoxicity and is currently trying to understand the effects perinatal cannabinoid exposure on brain development. Using a combination of techniques including animal behavior, genomics, and neuronal ultrastructure analysis, he hopes to define critical windows of sensitivity to these drugs to provide safety information around their use and to also understand how the endogenous cannabinoid system regulates neurodevelopment.
Publications:
Chinn GA, Gray AT, Larson MD. Overcoming Obstacles: The Legacy of Fidel Pagés, Founder of the Epidural, 100 Years After His Passing. Anesth Analg. 2024 Feb 01; 138(2):475-479.
Schober A, Chinn G, Eichbaum Y, Dudley M, Sall JW, University of California San Francisco AR36 working group. A Randomized Phase 2 Study to Evaluate Efficacy and Safety of AR36 for Prevention of Acute Mountain Sickness. Wilderness Environ Med. 2023 Dec; 34(4):498-508.
Soni I, Chinn GA, Halifax JC, Hellman J, Lynch KL, Sall JW. The Effect of Route of Administration and Vehicle on the Pharmacokinetics of THC and CBD in Adult, Neonate, and Breastfed Sprague-Dawley Rats. Cannabis Cannabinoid Res. 2023 Oct 18.
Chinn GA, Cummins MH, Sall JW. A Spatial Memory Deficit in Male But Not Female Rats After Neonatal Diazepam Exposure: A New Model for Developmental Sedative Neurotoxicity. Anesth Analg. 2023 Jun 22.
Chinn GA, Duong K, Horovitz TR, Sasaki Russell JM, Sall JW. Testosterone is Sufficient to Impart Susceptibility to Isoflurane Neurotoxicity in Female Neonatal Rats. J Neurosurg Anesthesiol. 2022 10 01; 34(4):429-436.
Chinn GA, Sasaki Russell JM, Yabut NA, Maharjan D, Sall JW. Androgenic Modulation of the Chloride Transporter NKCC1 Contributes to Age-dependent Isoflurane Neurotoxicity in Male Rats. Anesthesiology. 2020 10 01; 133(4):852-866.
Chinn GA, Pearn ML, Vutskits L, Mintz CD, Loepke AW, Lee JJ, Chen J, Bosnjak ZJ, Brambrink AM, Jevtovic-Todorovic V, Sun LS, Sall JW. Standards for preclinical research and publications in developmental anaesthetic neurotoxicity: expert opinion statement from the SmartTots preclinical working group. Br J Anaesth. 2020 May; 124(5):585-593.
Chinn GA, Sasaki Russell JM, Banh ET, Lee SC, Sall JW. Voluntary Exercise Rescues the Spatial Memory Deficit Associated With Early Life Isoflurane Exposure in Male Rats. Anesth Analg. 2019 11; 129(5):1365-1373.
Chinn G, Guan Z. Case Report and Literature Review: Interventional Management of Erythromelalgia. Transl Perioper Pain Med. 2019; 6(4):91-97.
Sasaki Russell JM, Chinn GA, Maharjan D, Eichbaum Y, Sall JW. Female rats are more vulnerable to lasting cognitive impairment after isoflurane exposure on postnatal day 4 than 7. Br J Anaesth. 2019 Apr; 122(4):490-499.
Chinn GA, Sasaki Russell JM, Sall JW. Is a short anesthetic exposure in children safe? Time will tell: a focused commentary of the GAS and PANDA trials. Ann Transl Med. 2016 Oct; 4(20):408.
Chinn GA, Hirokawa KE, Chuang TM, Urbina C, Patel F, Fong J, Funatsu N, Monuki ES. Agenesis of the Corpus Callosum Due to Defective Glial Wedge Formation in Lhx2 Mutant Mice. Cereb Cortex. 2015 Sep; 25(9):2707-18.
Berchtold NC, Chinn G, Chou M, Kesslak JP, Cotman CW. Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus. Neuroscience. 2005; 133(3):853-61.