David Shimabukuro, MD

Clinical Professor
Medical-Surgical 13ICU Medical Director
Medical Director, Sepsis Program
Publications: 
Mohamadlou H, Panchavati S, Calvert J, Lynn-Palevsky A, Le S, Allen A, Pellegrini E, Green-Saxena A, Barton C, Fletcher G, Shieh L, Stark PB, Chettipally U, Shimabukuro D, Feldman M, Das R. Multicenter validation of a machine-learning algorithm for 48-h all-cause mortality prediction. Health Informatics J. 2019 Dec 30; 1460458219894494.
Sung N, Aldrich JM, Shimabukuro DW, Matthay MA, Liu KD. Assessing Preventable Harms in the Intensive Care Unit: Data From a Tertiary Care Academic Medical Institution. Am J Med Qual. 2018 May/Jun; 33(3):329.
Mao Q, Jay M, Hoffman JL, Calvert J, Barton C, Shimabukuro D, Shieh L, Chettipally U, Fletcher G, Kerem Y, Zhou Y, Das R. Multicentre validation of a sepsis prediction algorithm using only vital sign data in the emergency department, general ward and ICU. BMJ Open. 2018 01 26; 8(1):e017833.
Shimabukuro DW, Barton CW, Feldman MD, Mataraso SJ, Das R. Effect of a machine learning-based severe sepsis prediction algorithm on patient survival and hospital length of stay: a randomised clinical trial. BMJ Open Respir Res. 2017; 4(1):e000234.
Prasad PA, Shea ER, Shiboski S, Sullivan MC, Gonzales R, Shimabukuro D. Relationship Between a Sepsis Intervention Bundle and In-Hospital Mortality Among Hospitalized Patients: A Retrospective Analysis of Real-World Data. Anesth Analg. 2017 08; 125(2):507-513.
Calvert J, Hoffman J, Barton C, Shimabukuro D, Ries M, Chettipally U, Kerem Y, Jay M, Mataraso S, Das R. Cost and mortality impact of an algorithm-driven sepsis prediction system. J Med Econ. 2017 Jun; 20(6):646-651.
Desautels T, Calvert J, Hoffman J, Jay M, Kerem Y, Shieh L, Shimabukuro D, Chettipally U, Feldman MD, Barton C, Wales DJ, Das R. Prediction of Sepsis in the Intensive Care Unit With Minimal Electronic Health Record Data: A Machine Learning Approach. JMIR Med Inform. 2016 Sep 30; 4(3):e28.
Anne L. Donovan, David Shimabukuro. Protocol-Based Management of Severe Sepsis and Septic Shock. Current Anesthesiology Reports. 2015 Dec 1; 5(4):407-418.
Janice Man, John Feiner, David Shimabukuro. 949. Critical Care Medicine. 2014 Dec 1; 42(12):a1589.
David Shimabukuro. Chapter 3 Cardiopulmonary Resuscitation. Critical Care Secrets. 2013 Jan 1; 20-27.
David Shimabukuro, Richard H. Savel, Michael A. Gropper. Chapter 32 Sepsis, Severe Sepsis, and Septic Shock. Critical Care Secrets. 2013 Jan 1; 217-222.
Michel Kearns, David Shimabukuro. Respiratory Complications and Management of Mechanical Ventilation in Cervical Spine Injury. ICU Director. 2012 Sep 1; 3(5):220-223.
Weiskopf RB, Feiner J, Toy P, Twiford J, Shimabukuro D, Lieberman J, Looney MR, Lowell CA, Gropper MA. Fresh and stored red blood cell transfusion equivalently induce subclinical pulmonary gas exchange deficit in normal humans. Anesth Analg. 2012 Mar; 114(3):511-9.
David Shimabukuro. Acute Care Nurse Practitioners in an Academic Multidisciplinary ICU. ICU Director. 2011 Jan 1; 2(1-2):28-30.
David Shimabukuro, Linda L. Liu. Chapter 44 Cardiopulmonary Resuscitation. Basics of Anesthesia. 2011 Jan 1; 715-728.
Liu LL, Aldrich JM, Shimabukuro DW, Sullivan KR, Taylor JM, Thornton KC, Gropper MA. Special article: rescue therapies for acute hypoxemic respiratory failure. Anesth Analg. 2010 Sep; 111(3):693-702.
Shimabukuro DW, Gropper MA. Noisy mechanical ventilation: listen to the melody. Anesthesiology. 2009 Feb; 110(2):214-5.
Jeanine P. Wiener-Kronish, David W. Shimabukuro. Chapter 20 Airway Management. Clinical Respiratory Medicine. 2008 Jan 1; (Anesthesiology781993):267-274.
David Shimabukuro. Chapter 2 Cardiopulmonary Resuscitation. Critical Care Secrets. 2007 Jan 1; 14-20.
David Shimabukuro. Chapter 87 Ethics. Critical Care Secrets. 2007 Jan 1; 549-553.
David Shimabukuro. Chapter 88 Withdrawal of Treatment. Critical Care Secrets. 2007 Jan 1; 554-556.
Faure K, Fujimoto J, Shimabukuro DW, Ajayi T, Shime N, Moriyama K, Spack EG, Wiener-Kronish JP, Sawa T. Effects of monoclonal anti-PcrV antibody on Pseudomonas aeruginosa-induced acute lung injury in a rat model. J Immune Based Ther Vaccines. 2003 Aug 13; 1(1):2.
Shimabukuro DW, Sawa T, Gropper MA. Injury and repair in lung and airways. Crit Care Med. 2003 Aug; 31(8 Suppl):S524-31.
Faure K, Shimabukuro D, Ajayi T, Allmond LR, Sawa T, Wiener-Kronish JP. O-antigen serotypes and type III secretory toxins in clinical isolates of Pseudomonas aeruginosa. J Clin Microbiol. 2003 May; 41(5):2158-60.