Biography Danielle is a proud native of the Pacific Northwest. She completed her MD-PhD at Oregon Health & Science University, before joining the Department of Anesthesia at UCSF as an anesthesia resident and has since completed a fellowship in Critical Care Medicine, and a post-doctoral fellowship in the Sall Lab. Her current research interests include understanding how adaptive and maladaptive responses to physiologic stressors such as hypoxia can help us better understand and treat critical illness. In her free time, Danielle enjoys running dirt trails, climbing snow-covered mountains, and exploring the wilderness. Role Faculty Location UCSF at Mission Bay UCSF at Mount Zion UCSF at Parnassus Category Clinical Research Specialties Critical Care Medicine Education 2022 - Critical Care, University of California, San Francisco2021 - Anesthesia, University of California, San FranciscoMD, 2017 - , Oregon Health & Science UniversityPhD, 2015 - Biochemistry, Oregon Health & Science University - Internship, Providence St Vincent Medical Center Publications Cystic fibrosis in children: A pediatric anesthesiologist's perspective. Williamson DM, Sharma A Mechanism of Fine-tuning pH Sensors in Proprotein Convertases: IDENTIFICATION OF A pH-SENSING HISTIDINE PAIR IN THE PROPEPTIDE OF PROPROTEIN CONVERTASE 1/3. Williamson DM, Elferich J, Shinde U Determination of Histidine pKa Values in the Propeptides of Furin and Proprotein Convertase 1/3 Using Histidine Hydrogen-Deuterium Exchange Mass Spectrometry. Elferich J, Williamson DM, David LL, Shinde U The mechanism by which a propeptide-encoded pH sensor regulates spatiotemporal activation of furin. Williamson DM, Elferich J, Ramakrishnan P, Thomas G, Shinde U Propeptides of eukaryotic proteases encode histidines to exploit organelle pH for regulation. Elferich J, Williamson DM, Krishnamoorthy B, Shinde U Propeptides are sufficient to regulate organelle-specific pH-dependent activation of furin and proprotein convertase 1/3. Dillon SL, Williamson DM, Elferich J, Radler D, Joshi R, Thomas G, Shinde U Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action. Dikeakos JD, Atkins KM, Thomas L, Emert-Sedlak L, Byeon IJ, Jung J, Ahn J, Wortman MD, Kukull B, Saito M, Koizumi H, Williamson DM, Hiyoshi M, Barklis E, Takiguchi M, Suzu S, Gronenborn AM, Smithgall TE, Thomas G Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis. Aslan JE, You H, Williamson DM, Endig J, Youker RT, Thomas L, Shu H, Du Y, Milewski RL, Brush MH, Possemato A, Sprott K, Fu H, Greis KD, Runckel DN, Vogel A, Thomas G