Biography My group is interested in identifying why obese individuals are at greater risk of liver injury in the setting of trauma or surgery. My long-term goal is to understand the relationship between metabolic and immunologic processes in the liver. One potential link between these underlying mechanisms could be the peptide leptin, which can profoundly modify inflammatory and metabolic pathways. The goal of this research effort is to improve understanding of the impact of leptin on acute inflammatory cascade and metabolic response during hepatic ischemia-reperfusion. This will benefit patients by improving risk-stratification of candidates for hepatic surgery and possibly lead to preventive therapies for ischemia-reperfusion injury. Role Faculty Category Clinical Research Specialties Liver Transplant Publications Therapeutic Hypothermia in Low-Risk Nonpumped Brain-Dead Kidney Donors: A Randomized Clinical Trial. Patel MS, Salcedo-Betancourt JD, Saunders C, Broglio K, Malinoski D, Niemann CU JAMA network open . Feb 5, 2024 International Liver Transplantation Society Global Census: First Look at Pediatric Liver Transplantation Activity Around the World. Rodriguez-Davalos MI, Lopez-Verdugo F, Kasahara M, Muiesan P, Reddy MS, Flores-Huidobro Martinez A, Xia Q, Hong JC, Niemann CU, Seda-Neto J, Miloh TA, Yi NJ, Mazariegos GV, Ng VL, Esquivel CO, Lerut J, Rela M, Pediatric Liver Transplantation Global Census Group Transplantation . Sep 25, 2023 Lactate concentration at the end of liver transplant: Early predictor of graft function or just one piece of the puzzle? Galli AM, Kothari R, Adelmann D, Holm Z, Bokoch MP, De Gasperi A, Niemann CU, Kolodzie K Clinical transplantation . Jun 23, 2023 Hypothermia or Machine Perfusion in Kidney Donors. Malinoski D, Saunders C, Swain S, Groat T, Wood PR, Reese J, Nelson R, Prinz J, Kishish K, Van De Walker C, Geraghty PJ, Broglio K, Niemann CU The New England journal of medicine . Feb 2, 2023 Enhanced recovery for liver transplantation: recommendations from the 2022 International Liver Transplantation Society consensus conference. Pollok JM, Tinguely P, Berenguer M, Niemann CU, Raptis DA, Spiro M, ERAS4OLT.org collaborative The lancet. Gastroenterology & hepatology . Jan 1, 2023 Perioperative mortality in liver transplantation before and after the implementation of the organ allocation policy Share 35. Holm ZD, Kolodzie K, Galli AM, Meyhoff CS, Niemann CU, Adelmann D Clinical transplantation . Dec 7, 2022 Advantages and Limitations of Clinical Scores for Donation After Circulatory Death Liver Transplantation. Meier RPH, Kelly Y, Yamaguchi S, Braun HJ, Lunow-Luke T, Adelmann D, Niemann C, Maluf DG, Dietch ZC, Stock PG, Kang SM, Feng S, Posselt AM, Gardner JM, Syed SM, Hirose R, Freise CE, Ascher NL, Roberts JP, Roll GR Frontiers in surgery . Jan 5, 2022 Expedited evaluation for liver transplantation: A critical look at processes and outcomes. Braun HJ, Mello A, Kothari R, Ku E, Yilma M, Tavakol M, Zhang L, Niemann CU, Ascher NL, Adelmann D Clinical transplantation . Dec 23, 2021 Organ donor management goals and delayed graft function in adult kidney transplant recipients. Kothari R, Tolles J, Adelmann D, Lewis RJ, Malinoski DJ, Niemann CU Clinical transplantation . Nov 16, 2021 Perioperative Normal Saline Administration and Delayed Graft Function in Patients Undergoing Kidney Transplantation: A Retrospective Cohort Study. Kolodzie K, Cakmakkaya OS, Boparai ES, Tavakol M, Feiner JR, Kim MO, Newman TB, Niemann CU Anesthesiology . Oct 1, 2021 Machine Learning Prediction of Liver Allograft Utilization From Deceased Organ Donors Using the National Donor Management Goals Registry. Bishara AM, Lituiev DS, Adelmann D, Kothari RP, Malinoski DJ, Nudel JD, Sally MB, Hirose R, Hadley DD, Niemann CU Transplantation direct . Sep 27, 2021 Enhanced recovery after surgery programs improve short-term outcomes after liver transplantation-A systematic review and meta-analysis. Tinguely P, Morare N, Ramirez-Del Val A, Berenguer M, Niemann CU, Pollok JM, Raptis DA, Spiro M Clinical transplantation . Sep 16, 2021 Assessment of the global practice of living donor liver transplantation. Emamaullee J, Conrad C, Kim M, Goldbeck C, Kwon Y, Singh P, Niemann CU, Sher L, Genyk Y Transplant international : official journal of the European Society for Organ Transplantation . Sep 14, 2021 Raster Thomson scattering in large-scale laser plasmas produced at high repetition rate. Kaloyan M, Ghazaryan S, Constantin CG, Dorst RS, Heuer PV, Pilgram JJ, Schaeffer DB, Niemann C The Review of scientific instruments . Sep 1, 2021 Critical care and ventilatory management of deceased organ donors impact lung use and recipient graft survival. Swanson EA, Patel MS, Hutchens MP, Niemann CU, Groat T, Malinoski DJ, Sally MB American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons . Jul 10, 2021 Shared B cell memory to coronaviruses and other pathogens varies in human age groups and tissues. Yang F, Nielsen SCA, Hoh RA, Röltgen K, Wirz OF, Haraguchi E, Jean GH, Lee JY, Pham TD, Jackson KJL, Roskin KM, Liu Y, Nguyen K, Ohgami RS, Osborne EM, Nadeau KC, Niemann CU, Parsonnet J, Boyd SD Science (New York, N.Y.) . Apr 12, 2021 Prospective Multicenter Study of Early Antiviral Therapy in Liver and Kidney Transplant Recipients of HCV-Viremic Donors. Terrault NA, Burton J, Ghobrial M, Verna E, Bayer J, Klein C, Victor D, Mohan S, Trotter J, Dodge J, Niemann CU, Rubin RA Hepatology (Baltimore, Md.) . Jan 22, 2021 Weighing the waitlist: Weight changes and access to kidney transplantation among obese candidates. Ku E, Whelan AM, McCulloch CE, Lee B, Niemann CU, Roll GR, Grimes BA, Johansen KL PloS one . Nov 30, 2020 COVID-19 and Abdominal Transplant: A Stepwise Approach to Practice During Pandemic Conditions. Syed SM, Gardner J, Roll G, Webber A, Mehta N, Shoji J, Adelmann D, Niemann C, Braun HJ, Mello A, Yao F, Posselt A, Kang SM, Hirose R, Roberts J, Feng S, Ascher N, Stock P, Freise C Transplantation . Nov 1, 2020 The Association Between Vena Cava Implantation Technique and Acute Kidney Injury After Liver Transplantation. Hannon V, Kothari RP, Zhang L, Bokoch MP, Hill R, Roll GR, Mello A, Feiner JR, Liu KD, Niemann CU, Adelmann D Transplantation . Nov 1, 2020 Measurements of ion velocity distributions in a large scale laser-produced plasma. Dorst RS, Heuer PV, Schaeffer DB, Constantin CG, Niemann C The Review of scientific instruments . Oct 1, 2020 Longer Distance From Dialysis Facility to Transplant Center Is Associated With Lower Access to Kidney Transplantation. Whelan AM, Johansen KL, McCulloch CE, Adelmann D, Niemann CU, Roll GR, Siyahian S, Grimes B, Ku E Transplantation direct . Sep 17, 2020 Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation. Iske J, Seyda M, Heinbokel T, Maenosono R, Minami K, Nian Y, Quante M, Falk CS, Azuma H, Martin F, Passos JF, Niemann CU, Tchkonia T, Kirkland JL, Elkhal A, Tullius SG Nature communications . Aug 27, 2020 Impact of Deceased Donor Management on Donor Heart Use and Recipient Graft Survival. Swanson EA, Adams T, Patel MS, De La Cruz S, Hutchens M, Khush K, Sally MB, Niemann CU, Groat T, Malinoski DJ Journal of the American College of Surgeons . Jun 17, 2020 Bacchus Listed for a Liver Transplant: Comment. Niemann CU Anesthesiology . Jun 1, 2020 Vasopressor selection during critical care management of brain dead organ donors and the effects on kidney graft function. Swanson EA, Patel MS, Groat T, Jameson NE, Ellis MKM, Hutchens MP, Niemann CU, Malinoski DJ, Sally MB The journal of trauma and acute care surgery . Jun 1, 2020 The role of deceased donor liver biopsy: An analysis of 5449 liver transplant recipients. Patel MS, Mohebali J, Coe TM, Sally M, Groat T, Niemann CU, Malinoski DJ, Vagefi PA Clinical transplantation . Mar 23, 2020 Transplant anesthesia and critical care: Current research and possible future developments. Niemann CU, Biancofiore G Best practice & research. Clinical anaesthesiology . Mar 12, 2020 Therapeutic Hypothermia in Organ Donors: Follow-up and Safety Analysis. Malinoski D, Patel MS, Axelrod DA, Broglio K, Lewis RJ, Groat T, Niemann CU Transplantation . Nov 1, 2019 Modeling the economic benefit of targeted mild hypothermia in deceased donor kidney transplantation. Axelrod DA, Malinoski D, Patel MS, Broglio K, Lewis R, Groat T, Lentine KL, Schnitzler M, Niemann CU Clinical transplantation . Jul 1, 2019 The Continued Need for Clinical Trials in Deceased Organ Donor Management. Niemann CU, Matthay MA, Ware LB Transplantation . Jul 1, 2019 Deceased organ donor factors influencing pancreatic graft transplantation and survival. Sally MB, Ellis MK, Hutchens M, Groat T, Swanson E, Patel MS, Niemann CU, Malinoski DJ Clinical transplantation . Jun 1, 2019 The Impact of Deceased Donor Liver Extraction Time on Early Allograft Function in Adult Liver Transplant Recipients. Adelmann D, Roll GR, Kothari R, Syed S, Burdine LJ, Tavakol M, Niemann CU Transplantation . Nov 1, 2018 Intraoperative Management of Liver Transplant Patients Without the Routine Use of Renal Replacement Therapy. Adelmann D, Olmos A, Liu LL, Feiner JR, Roll GR, Burdine L, Tavakol M, Syed S, Orandi BJ, Niemann CU Transplantation . May 1, 2018 Central venous pressure monitoring in living donor kidney recipients does not affect immediate graft function: A propensity score analysis. Adelmann D, Bicknell L, Niemann CU, Feiner J, Roll GR, Burdine L, Whitlock EL Clinical transplantation . Mar 30, 2018 Organ Donor Management: Part 1. Toward a Consensus to Guide Anesthesia Services During Donation After Brain Death. Souter MJ, Eidbo E, Findlay JY, Lebovitz DJ, Moguilevitch M, Neidlinger NA, Wagener G, Paramesh AS, Niemann CU, Roberts PR, Pretto EA Seminars in cardiothoracic and vascular anesthesia . Dec 24, 2017 Comments on "Impact of spontaneous donor hypothermia on graft outcomes after kidney transplantation". Niemann CU, Broglio K, Malinoski D American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons . Dec 9, 2017 Potentially inappropriate liver transplantation in the era of the "sickest first" policy - A search for the upper limits. Linecker M, Krones T, Berg T, Niemann CU, Steadman RH, Dutkowski P, Clavien PA, Busuttil RW, Truog RD, Petrowsky H Journal of hepatology . Nov 11, 2017 Protecting the Kidney in Liver Transplant Recipients: Practice-Based Recommendations From the American Society of Transplantation Liver and Intestine Community of Practice. Levitsky J, O'Leary JG, Asrani S, Sharma P, Fung J, Wiseman A, Niemann CU American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons . Apr 22, 2016 Therapeutic Hypothermia in Deceased Organ Donors and Kidney-Graft Function. Niemann CU, Malinoski D The New England journal of medicine . Dec 31, 2015 Impact of a quality improvement project on deceased organ donor management. Olmos A, Feiner J, Hirose R, Swain S, Blasi A, Roberts JP, Niemann CU Progress in transplantation (Aliso Viejo, Calif.) . Dec 1, 2015 Therapeutic Hypothermia in Deceased Organ Donors and Kidney-Graft Function. Niemann CU, Feiner J, Swain S, Bunting S, Friedman M, Crutchfield M, Broglio K, Hirose R, Roberts JP, Malinoski D The New England journal of medicine . Jul 30, 2015 Management of the Potential Organ Donor in the ICU: Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Consensus Statement. Kotloff RM, Blosser S, Fulda GJ, Malinoski D, Ahya VN, Angel L, Byrnes MC, DeVita MA, Grissom TE, Halpern SD, Nakagawa TA, Stock PG, Sudan DL, Wood KE, Anillo SJ, Bleck TP, Eidbo EE, Fowler RA, Glazier AK, Gries C, Hasz R, Herr D, Khan A, Landsberg D, Lebovitz DJ, Levine DJ, Mathur M, Naik P, Niemann CU, Nunley DR, O'Connor KJ, Pelletier SJ, Rahman O, Ranjan D, Salim A, Sawyer RG, Shafer T, Sonneti D, Spiro P, Valapour M, Vikraman-Sushama D, Whelan TP, Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurem Critical Care Medicine . Jun 1, 2015 The Impact of Hydroxyethyl Starch Use in Deceased Organ Donors on the Development of Delayed Graft Function in Kidney Transplant Recipients: A Propensity-Adjusted Analysis. Patel MS, Niemann CU, Sally MB, De La Cruz S, Zatarain J, Ewing T, Crutchfield M, Enestvedt CK, Malinoski DJ American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons . Apr 22, 2015 A role for Rac1 activity in malignant progression of sebaceous skin tumors. Frances D, Sharma N, Pofahl R, Maneck M, Behrendt K, Reuter K, Krieg T, Klein CA, Haase I, Niemann C Oncogene . Feb 9, 2015 Exercise-induced changes in basal ganglia volume and cognition in older adults. Niemann C, Godde B, Staudinger UM, Voelcker-Rehage C Neuroscience . Sep 22, 2014 Abdominal transplantation. Niemann CU Anesthesiology clinics . Nov 6, 2013 Patients with chronic kidney disease. Kalamas AG, Niemann CU The Medical clinics of North America . Sep 21, 2013 Peri-operative hyperglycemia is associated with delayed graft function in deceased donor renal transplantation. Parekh J, Roll GR, Feng S, Niemann CU, Hirose R Clinical transplantation . Jun 30, 2013 Functional elements associated with hepatic regeneration in living donors after right hepatic lobectomy. Everson GT, Hoefs JC, Niemann CU, Olthoff KM, Dupuis R, Lauriski S, Herman A, Milne N, Gillespie BW, Goodrich NP, Everhart JE Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society . Mar 1, 2013 Deceased organ donor research: the last research frontier? Mone T, Heldens J, Niemann CU Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society . Feb 1, 2013 Liver transplantation outcome in patients with angiographically proven coronary artery disease: a multi-institutional study. Wray C, Scovotti JC, Tobis J, Niemann CU, Planinsic R, Walia A, Findlay J, Wagener G, Cywinski JB, Markovic D, Hughes C, Humar A, Olmos A, Sierra R, Busuttil R, Steadman RH American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons . Nov 5, 2012 Infrared pupillometry to detect the light reflex during cardiopulmonary resuscitation: a case series. Behrends M, Niemann CU, Larson MD Resuscitation . May 30, 2012 Optimizing cost-effectiveness in perioperative care for liver transplantation: a model for low- to medium-income countries. Rando K, Niemann CU, Taura P, Klinck J Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society . Nov 1, 2011 Intraoperative hyperglycemia augments ischemia reperfusion injury in renal transplantation: a prospective study. Parekh J, Niemann CU, Dang K, Hirose R Journal of transplantation . Sep 4, 2011 Transplant critical care: standards for intensive care of the patient with liver failure before and after transplantation. Niemann CU, Kramer DJ Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society . May 1, 2011 Intraoperative management of liver transplant patients. Liu LL, Niemann CU Transplantation reviews (Orlando, Fla.) . Apr 21, 2011 Donor pre-treatment with everolimus or cyclosporine does not reduce ischaemia-reperfusion injury in a rat kidney transplant model. Martinez-Palli G, Hirose R, Liu T, Xu F, Dang K, Feiner J, Serkova NJ, Niemann CU Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association . Nov 10, 2010 Multivessel coronary artery disease predicts mortality, length of stay, and pressor requirements after liver transplantation. Yong CM, Sharma M, Ochoa V, Abnousi F, Roberts J, Bass NM, Niemann CU, Shiboski S, Prasad M, Tavakol M, Ports TA, Gregoratos G, Yeghiazarians Y, Boyle AJ Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society . Nov 1, 2010 Liver transplant perioperative pathways: which way towards high-quality care and better outcomes? Biancofiore G, Niemann CU Minerva anestesiologica . Oct 1, 2010 Mapping the ionization state of laser-irradiated Ar gas jets with multiwavelength monochromatic x-ray imaging. Kugland NL, Döppner T, Kemp A, Schaeffer D, Glenzer SH, Niemann C The Review of scientific instruments . Oct 1, 2010 1H-NMR-based metabolic signatures of clinical outcomes in trauma patients--beyond lactate and base deficit. Cohen MJ, Serkova NJ, Wiener-Kronish J, Pittet JF, Niemann CU The Journal of trauma . Jul 1, 2010 Chronic kidney disease: implications for the perioperative period. Eilers H, Liu KD, Gruber A, Niemann CU Minerva anestesiologica . Jun 28, 2010 Induction of intestinal ischemia reperfusion injury by portal vein outflow occlusion in rats. Vincenti M, Behrends M, Dang K, Park YH, Hirose R, Blasi-Ibanez A, Liu T, Serkova NJ, Niemann CU Journal of gastroenterology . Jun 15, 2010 Quality improvement in transplant anesthesia: which way forward? Niemann CU, Feiner J Current opinion in organ transplantation . Jun 1, 2010 Short passive cooling protects rats during hepatectomy by inducing heat shock proteins and limiting the induction of pro-inflammatory cytokines. Niemann CU, Xu F, Choi S, Behrends M, Park Y, Hirose R, Maher JJ The Journal of surgical research . Jan 1, 2010 Evolution of elastic x-ray scattering in laser-shocked warm dense lithium. Kugland NL, Gregori G, Bandyopadhyay S, Brenner CM, Brown CR, Constantin C, Glenzer SH, Khattak FY, Kritcher AL, Niemann C, Otten A, Pasley J, Pelka A, Roth M, Spindloe C, Riley D Physical review. E, Statistical, nonlinear, and soft matter physics . Dec 17, 2009 Acute hyperglycemia worsens hepatic ischemia/reperfusion injury in rats. Behrends M, Martinez-Palli G, Niemann CU, Cohen S, Ramachandran R, Hirose R Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract . Dec 9, 2009 Acute kidney injury during liver transplantation as determined by neutrophil gelatinase-associated lipocalin. Niemann CU, Walia A, Waldman J, Davio M, Roberts JP, Hirose R, Feiner J Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society . Dec 1, 2009 Abdominal organ transplantation. Niemann CU, Eilers H Minerva anestesiologica . Nov 24, 2009 Systemic inflammation, coagulopathy, and acute renal insufficiency following endovascular thoracoabdominal aortic aneurysm repair. Chang CK, Chuter TA, Niemann CU, Shlipak MG, Cohen MJ, Reilly LM, Hiramoto JS Journal of vascular surgery . May 1, 2009 Predictors associated with terminal renal function in deceased organ donors in the intensive care unit. Blasi-Ibanez A, Hirose R, Feiner J, Freise C, Stock PG, Roberts JP, Niemann CU Anesthesiology . Feb 1, 2009 Postoperative infectious complications of abdominal solid organ transplantation. Hlava N, Niemann CU, Gropper MA, Melcher ML Journal of intensive care medicine . Nov 17, 2008 High contrast Kr gas jet K alpha x-ray source for high energy density physics experiments. Kugland NL, Neumayer P, Döppner T, Chung HK, Constantin CG, Girard F, Glenzer SH, Kemp A, Niemann C The Review of scientific instruments . Oct 1, 2008 Alterations in the proteome of pulmonary alveolar type II cells in the rat after hepatic ischemia-reperfusion. Hirsch J, Niemann CU, Hansen KC, Choi S, Su X, Frank JA, Fang X, Hirose R, Theodore P, Sapru A, Burlingame AL, Matthay MA Critical Care Medicine . Jun 1, 2008 Perioperative liver transplant best practices: weighing the evidence. Mandell MS, Niemann CU Current opinion in organ transplantation . Jun 1, 2008 Transient hyperglycemia affects the extent of ischemia-reperfusion-induced renal injury in rats. Hirose R, Xu F, Dang K, Liu T, Behrends M, Brakeman PR, Wiener-Kronish J, Niemann CU Anesthesiology . Mar 1, 2008 Green frequency-doubled laser-beam propagation in high-temperature hohlraum plasmas. Niemann C, Berger RL, Divol L, Froula DH, Jones O, Kirkwood RK, Meezan N, Moody JD, Ross J, Sorce C, Suter LJ, Glenzer SH Physical review letters . Jan 29, 2008 Increased severity of renal ischemia-reperfusion injury with venous clamping compared to arterial clamping in a rat model. Park Y, Hirose R, Dang K, Xu F, Behrends M, Tan V, Roberts JP, Niemann CU Surgery . Dec 27, 2007 A multicenter evaluation of safety of early extubation in liver transplant recipients. Mandell MS, Stoner TJ, Barnett R, Shaked A, Bellamy M, Biancofiore G, Niemann C, Walia A, Vater Y, Tran ZV, Kam I Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society . Nov 1, 2007 Remote renal injury following partial hepatic ischemia/reperfusion injury in rats. Behrends M, Hirose R, Park YH, Tan V, Dang K, Xu F, Park SH, Niemann CU Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract . Aug 14, 2007 Biochemical mechanisms of nephrotoxicity: application for metabolomics. Niemann CU, Serkova NJ Expert opinion on drug metabolism & toxicology . Aug 1, 2007 Early detection of graft failure using the blood metabolic profile of a liver recipient. Serkova NJ, Zhang Y, Coatney JL, Hunter L, Wachs ME, Niemann CU, Mandell MS Transplantation . Feb 27, 2007 Glutamine donor pretreatment in rat kidney transplants with severe preservation reperfusion injury. Fuller TF, Rose F, Singleton KD, Linde Y, Hoff U, Freise CE, Dragun D, Niemann CU The Journal of surgical research . Feb 9, 2007 Central venous pressure monitoring during living right donor hepatectomy. Niemann CU, Feiner J, Behrends M, Eilers H, Ascher NL, Roberts JP Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society . Feb 1, 2007 Ischemia-reperfusion injury is more severe in older versus young rat livers. Park Y, Hirose R, Coatney JL, Ferrell L, Behrends M, Roberts JP, Serkova NJ, Niemann CU The Journal of surgical research . Oct 24, 2006 Pattern recognition and biomarker validation using quantitative 1H-NMR-based metabolomics. Serkova NJ, Niemann CU Expert review of molecular diagnostics . Sep 1, 2006 Mild hypothermia reduces the inflammatory response and hepatic ischemia/reperfusion injury in rats. Behrends M, Hirose R, Serkova NJ, Coatney JL, Bedolli M, Yardi J, Park YH, Niemann CU Liver international : official journal of the International Association for the Study of the Liver . Aug 1, 2006 Mild hypothermia protects obese rats from fulminant hepatic necrosis induced by ischemia-reperfusion. Niemann CU, Choi S, Behrends M, Hirose R, Noh J, Coatney JL, Roberts JP, Serkova NJ, Maher JJ Surgery . Jul 28, 2006 Recombinant factor VIIa reduces transfusion requirements in liver transplant patients with high MELD scores. Niemann CU, Behrends M, Quan D, Eilers H, Gropper MA, Roberts JP, Hirose R Transfusion medicine (Oxford, England) . Apr 1, 2006 Warm ischemia-induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats. Hirsch J, Hansen KC, Choi S, Noh J, Hirose R, Roberts JP, Matthay MA, Burlingame AL, Maher JJ, Niemann CU Molecular & cellular proteomics : MCP . Feb 24, 2006 Glutamine does not protect against hepatic warm ischemia/reperfusion injury in rats. Noh J, Behrends M, Choi S, Bedolli MA, Yardi J, Hirose R, Niemann CU Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract . Feb 1, 2006 Ischemic preconditioning improves energy state and transplantation survival in obese Zucker rat livers. Niemann CU, Hirose R, Liu T, Behrends M, Brown JL, Kominsky DF, Roberts JP, Serkova N Anesthesia and analgesia . Dec 1, 2005 Metabolic profiling of livers and blood from obese Zucker rats. Serkova NJ, Jackman M, Brown JL, Liu T, Hirose R, Roberts JP, Maher JJ, Niemann CU Journal of hepatology . Aug 2, 2005 H-NMR-based metabolic signatures of mild and severe ischemia/reperfusion injury in rat kidney transplants. Serkova N, Fuller TF, Klawitter J, Freise CE, Niemann CU Kidney international . Mar 1, 2005 Mild hypothermia provides significant protection against ischemia/reperfusion injury in livers of obese and lean rats. Choi S, Noh J, Hirose R, Ferell L, Bedolli M, Roberts JP, Niemann CU Annals of surgery . Mar 1, 2005 Ischemic preconditioning improves rat kidney graft function after severe ischemia/reperfusion injury. Fuller TF, Freise CE, Feng S, Niemann CU Transplantation proceedings . Jan 1, 2005 Automated, fast, and sensitive quantification of drugs in human plasma by LC/LC-MS: quantification of 6 protease inhibitors and 3 nonnucleoside transcriptase inhibitors. Egge-Jacobsen W, Unger M, Niemann CU, Baluom M, Hirai S, Benet LZ, Christians U Therapeutic drug monitoring . Oct 1, 2004 Beta-adrenergic blockade affects initial drug distribution due to decreased cardiac output and altered blood flow distribution. Avram MJ, Krejcie TC, Henthorn TK, Niemann CU The Journal of pharmacology and experimental therapeutics . Jun 14, 2004 Intraoperative fluid management of living donor versus cadaveric liver transplant recipients. Niemann CU, Hirose R, Stock P, Roberts JP, Mandell S, Spencer Yost C Transplantation proceedings . Jun 1, 2004 Influence of donor pretreatment with N-acetylcysteine on ischemia/reperfusion injury in rat kidney grafts. Fuller TF, Serkova N, Niemann CU, Freise CE The Journal of urology . Mar 1, 2004 Sirolimus delays recovery of rat kidney transplants after ischemia-reperfusion injury. Fuller TF, Freise CE, Serkova N, Niemann CU, Olson JL, Feng S Transplantation . Dec 15, 2003 Mechanism of pupillary reflex dilation in awake volunteers and in organ donors. Yang LL, Niemann CU, Larson MD Anesthesiology . Dec 1, 2003 The effects of desflurane and propofol on portosystemic pressure in patients with portal hypertension. Mandell MS, Durham J, Kumpe D, Trotter JF, Everson GT, Niemann CU Anesthesia and analgesia . Dec 1, 2003 Organ-specific response to inhibition of mitochondrial metabolism by cyclosporine in the rat. Serkova N, Klawitter J, Niemann CU Transplant international : official journal of the European Society for Organ Transplantation . Jun 24, 2003 Clinically important drug interactions with intravenous anaesthetics in older patients. Eilers H, Niemann C Drugs & aging . Jan 1, 2003 Intraoperative hemodynamics and liver function in adult-to-adult living liver donors. Niemann CU, Roberts JP, Ascher NL, Yost CS Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society . Dec 1, 2002 Elimination of indocyanine green in the perioperative evaluation of donor liver function. Mandell MS, Wachs M, Niemann CU, Henthorn TK Anesthesia and analgesia . Nov 1, 2002 Cyclosporine can increase isoflurane MAC. Niemann CU, Stabernack C, Serkova N, Jacobsen W, Christians U, Eger EI Anesthesia and analgesia . Oct 1, 2002 Close association between the reduction in myocardial energy metabolism and infarct size: dose-response assessment of cyclosporine. Niemann CU, Saeed M, Akbari H, Jacobsen W, Benet LZ, Christians U, Serkova N The Journal of pharmacology and experimental therapeutics . Sep 1, 2002 Evaluation of the splanchnic circulation with indocyanine green pharmacokinetics in liver transplant patients. Niemann CU, Yost CS, Mandell S, Henthorn TK Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society . May 1, 2002 Comparison of the effects of cyclosporin a on the metabolism of perfused rat brain slices during normoxia and hypoxia. Serkova N, Donohoe P, Gottschalk S, Hainz C, Niemann CU, Bickler PE, Litt L, Benet LZ, Leibfritz D, Christians U Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism . Mar 1, 2002 Sirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brain. Serkova N, Jacobsen W, Niemann CU, Litt L, Benet LZ, Leibfritz D, Christians U British journal of pharmacology . Jul 1, 2001 Isoflurane alters the recirculatory pharmacokinetics of physiologic markers. Avram MJ, Krejcie TC, Niemann CU, Enders-Klein C, Shanks CA, Henthorn TK Anesthesiology . Jun 1, 2000 Indocyanine green kinetics characterize blood volume and flow distribution and their alteration by propranolol. Niemann CU, Henthorn TK, Krejcie TC, Shanks CA, Enders-Klein C, Avram MJ Clinical pharmacology and therapeutics . Apr 1, 2000 Ketamine distribution described by a recirculatory pharmacokinetic model is not stereoselective. Henthorn TK, Krejcie TC, Niemann CU, Enders-Klein C, Shanks CA, Avram MJ Anesthesiology . Dec 1, 1999 Modifications of blood volume alter the disposition of markers of blood volume, extracellular fluid, and total body water. Krejcie TC, Henthorn TK, Gentry WB, Niemann CU, Enders-Klein C, Shanks CA, Avram MJ The Journal of pharmacology and experimental therapeutics . Dec 1, 1999 The effect of halothane on the recirculatory pharmacokinetics of physiologic markers. Avram MJ, Krejcie TC, Niemann CU, Klein C, Gentry WB, Shanks CA, Henthorn TK Anesthesiology . Dec 1, 1997 A recirculatory model of the pulmonary uptake and pharmacokinetics of lidocaine based on analysis of arterial and mixed venous data from dogs. Krejcie TC, Avram MJ, Gentry WB, Niemann CU, Janowski MP, Henthorn TK Journal of pharmacokinetics and biopharmaceutics . Apr 1, 1997 Use of parallel Erlang density functions to analyze first-pass pulmonary uptake of multiple indicators in dogs. Krejcie TC, Jacquez JA, Avram MJ, Niemann CU, Shanks CA, Henthorn TK Journal of pharmacokinetics and biopharmaceutics . Dec 1, 1996 Recirculatory pharmacokinetic models of markers of blood, extracellular fluid and total body water administered concomitantly. Krejcie TC, Henthorn TK, Niemann CU, Klein C, Gupta DK, Gentry WB, Shanks CA, Avram MJ The Journal of pharmacology and experimental therapeutics . Sep 1, 1996
