Biography Dr. Xiaobing Yu is an anesthesiologist who collaborates with a health care team to improve quality of life and manage pain for patients with a wide array of chronic pain conditions. He provides innovative interventional procedures guided by ultrasound or fluoroscopy (an imaging technique using continuous X-rays) to treat many chronic and persistent pain conditions. These include mouth or face pain (such as trigeminal neuralgia), failed back surgery syndrome, facetogenic pain (involving the facet joints of the spine's vertebrae), neuropathic pain, complex regional pain syndrome and pain associated with cancer. Yu's research explores new treatments for neuropathic pain, with the goal of improving the standard of care for this chronic condition. After earning his medical degree at Peking Union Medical College, Yu completed a residency in anesthesiology at Brigham and Women's Hospital, an affiliate of Harvard Medical School. He completed a fellowship in pain medicine at UCSF before joining the faculty. Yu belongs to the American Society of Anesthesiologists, California Society of Anesthesiologists, American Society of Regional Anesthesia and Pain Medicine, and International Association for the Study of Pain. Yu has a strong commitment to medical education. He directs the chronic pain rotation for UCSF residents as well as a specialty training course in pain management. Role Faculty Location UCSF at Mount Zion Category Clinical Research Specialties Pain Medicine Education Fellowship, 2013 - Pain Medicine, UCSFResidency, 2012 - Anesthesiology, Harvard Medical SchoolResidency, 1996 - , Peking Union Medical College1994 - , Peking Union Medical College Publications ACVR1-activating mutation causes neuropathic pain and sensory neuron hyperexcitability in humans. Yu X, Ton AN, Niu Z, Morales BM, Chen J, Braz J, Lai MH, Barruet E, Liu H, Cheung K, Ali S, Chan T, Bigay K, Ho J, Nikolli I, Hansberry S, Wentworth K, Kriegstein A, Basbaum A, Hsiao EC Contribution of colony-stimulating factor 1 to neuropathic pain. Yu X, Basbaum A, Guan Z Cardiopulmonary and Neurologic Dysfunctions in Fibrodysplasia Ossificans Progressiva. Khan F, Yu X, Hsiao EC Maxillary Nerve-Mediated Postseptoplasty Nasal Allodynia: A Case Report. Sharma S, Ly W, Yu X Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain. Yu X, Liu H, Hamel KA, Morvan MG, Yu S, Leff J, Guan Z, Braz JM, Basbaum AI Rapid Isolation of Dorsal Root Ganglion Macrophages. Yu X, Leff J, Guan Z Integrating Patient-Controlled Analgesia Using Implanted Intrathecal Pumps for Postoperative Pain Management: A Case Report. Peniche A, Poree L, Schumacher M, Yu X T-cell acute leukemia 1 (TAL1) regulation of erythropoietin receptor and association with excessive erythrocytosis. Rogers H, Wang L, Yu X, Alnaeeli M, Cui K, Zhao K, Bieker JJ, Prchal J, Huang S, Weksler B, Noguchi CT Erythropoietin signaling promotes transplanted progenitor cell survival. Jia Y, Warin R, Yu X, Epstein R, Noguchi CT Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment. Yu X, Zou J, Ye Z, Hammond H, Chen G, Tokunaga A, Mali P, Li YM, Civin C, Gaiano N, Cheng L Kruppel-like factor 4 is essential for inflammatory monocyte differentiation in vivo. Alder JK, Georgantas RW, Hildreth RL, Kaplan IM, Morisot S, Yu X, McDevitt M, Civin CI Hypoxia alters progression of the erythroid program. Rogers HM, Yu X, Wen J, Smith R, Fibach E, Noguchi CT Modification of globin gene expression by RNA targeting strategies. Shen TJ, Rogers H, Yu X, Lin F, Noguchi CT, Ho C A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Ohm JE, McGarvey KM, Yu X, Cheng L, Schuebel KE, Cope L, Mohammad HP, Chen W, Daniel VC, Yu W, Berman DM, Jenuwein T, Pruitt K, Sharkis SJ, Watkins DN, Herman JG, Baylin SB HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Yu X, Alder JK, Chun JH, Friedman AD, Heimfeld S, Cheng L, Civin CI Tal1/SCL binding to pericentromeric DNA represses transcription. Wen J, Huang S, Pack SD, Yu X, Brandt SJ, Noguchi CT Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas. Esni F, Ghosh B, Biankin AV, Lin JW, Albert MA, Yu X, MacDonald RJ, Civin CI, Real FX, Pack MA, Ball DW, Leach SD Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells. Beleslin-Cokic BB, Cokic VP, Yu X, Weksler BB, Schechter AN, Noguchi CT High-efficiency stable gene transduction in primary human melanocytes using a lentiviral expression system. Dunlap S, Yu X, Cheng L, Civin CI, Alani RM Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Yu X, Zhan X, D'Costa J, Tanavde VM, Ye Z, Peng T, Malehorn MT, Yang X, Civin CI, Cheng L Erythropoietin receptor signalling is required for normal brain development. Yu X, Shacka JJ, Eells JB, Suarez-Quian C, Przygodzki RM, Beleslin-Cokic B, Lin CS, Nikodem VM, Hempstead B, Flanders KC, Costantini F, Noguchi CT Pathophysiology of a sickle cell trait mouse model: human alpha(beta)(S) transgenes with one mouse beta-globin allele. Noguchi CT, Gladwin M, Diwan B, Merciris P, Smith R, Yu X, Buzard G, Fitzhugh A, Keefer LK, Schechter AN, Mohandas N The human erythropoietin receptor gene rescues erythropoiesis and developmental defects in the erythropoietin receptor null mouse. Yu X, Lin CS, Costantini F, Noguchi CT Erythropoietin stimulates proliferation and interferes with differentiation of myoblasts. Ogilvie M, Yu X, Nicolas-Metral V, Pulido SM, Liu C, Ruegg UT, Noguchi CT Production and processing of erythropoietin receptor transcripts in brain. Chin K, Yu X, Beleslin-Cokic B, Liu C, Shen K, Mohrenweiser HW, Noguchi CT
