Ethan Winkler, MD, PhD

Asst Prof In Residence

[email protected]

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Center for Cerebrovascular Research

Biography

Dr. Ethan Winkler is a cerebrovascular neurosurgeon and scientist who provides comprehensive endovascular and open microsurgical care for vascular disorders of the brain, neck or spine. These conditions include brain aneurysms, arteriovenous malformations, cavernous malformations, arteriovenous fistulas, Moyamoya disease, stroke, and carotid artery disease.

Dr. Winkler's research focuses on understanding the biological basis of debilitating diseases that result in stroke with an emphasis on vascular malformations and aneurysms. He leads the Vascular Anomalies & Stroke Computation (VASC) Laboratory at UCSF. The lab brings together genomic, stem cell, and bioengineering technologies to understand the cell-specific genetic mechanisms that regulate the brain's vasculature in health and disease. To translate these findings back to the clinic, we are also developing new technologies, such as endovascular biopsy, to inform and to develop new, state-of-the-art precision therapeutics to reverse cerebrovascular pathology.

Dr. Winkler earned his MD and PhD at the University of Rochester School of Medicine & Dentistry. He completed his residency in neurological surgery at the University of California San Francisco. He then completed two post-graduate clinical fellowships in endovascular neurosurgery and cerebrovascular and skull base neurosurgery at the Barrow Neurological Institute.

Education

Clinical Fellowship, 2023 - Cerebrovascular & Skull Base Neurosurgery, Barrow Neurological Institute

Clinical Fellowship, 2022 - Endovascular Neurosurgery, Barrow Neurological Institute

Residency, 2021 - Neurological Surgery, University of California San Francisco

Postdoctoral Fellowship, 2019 - Genomics, University of California San Francisco

MD, PhD, 2014 - Medicine/Neurobiology, University of Rochester School of Medicine & Dentistry

BA, 2006 - Neuroscience, University of Southern California

Publications

Stereotactic radiosurgery versus observation for intracranial low-grade dural arteriovenous fistulas.

Becerril-Gaitan A, Peesh P, Liu C, Lee CC, Yang HC, Niranjan A, Lunsford LD, Wei Z, Hoang A, Sheehan J, Dayawansa S, Peker S, Samanci Y, Starke RM, Abdelsalam A, Kondziolka D, Bernstein K, Ming Y, Ikeda G, Kano H, Tripathi M, Liscak R, May J, Wang Q, Li W, Welch B, O'Con J, Amin-Hanjani S, Nguyen Q, Lanzino G, Brinjikji W, Hayakawa M, Samaniego E, Du R, Lai R, Derdeyn C, Abla A, Gross B, Albuquerque F, Lawton M, Kim L, Levitt M, Alaraj A, Winkler E, Chalouhi N, Hoh B, Bulters D, Durnford A, Satomi J, Tada Y, van Dijk JMC, Potgieser ARE, Laurent D, Osbun J, Bahmani B, Zipfel G, Chen CJ

Journal of neurology, neurosurgery, and psychiatry

Incubator-Free Organoid Culture in a Sealed Recirculatory System.

Rosen Y, Doganyigit K, Arul S, Wachtel E, Ehrlich D, Venuturimilli V, Mouzaya M, Oriaku S, Ndiforchu B, Kaurala G, Hernandez S, Moarefian M, Schweiger H, Cisneros A, Zeraatkar M, Geng J, Mostajo-Radji MA, Winkler E, Haussler D, Teodorescu M

bioRxiv : the preprint server for biology

Preoperative embolization improves local control and modulates gene expression in atypical WHO grade 2 meningioma.

Haddad AF, Ramesh R, Zakimi N, Chen JS, Quintana D, Gil E, Kabir AS, Sibih YE, Lugo BM, Bhalla S, Chen WC, Villanueva-Meyer JE, Narsinh KH, Magill ST, Morshed RA, Winkler E, Theodosopoulos PV, McDermott MW, Aghi MK, Raleigh DR

Rescue management of recurrent or growing non-acute subdural hematoma following standalone or adjunctive middle meningeal artery embolization: A case series and systematic review.

Orscelik A, Senol YC, Chaney E, Narsinh K, Amans M, Raper DM, Winkler E, Hetts S, Cooke D, Savastano LE

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences

Transcirculation retrograde placement of a Pipeline embolization device for treatment of a vertebrobasilar junction aneurysm.

Srinivasan VM, Graffeo CS, Scherschinski L, Majmundar N, Catapano JS, Winkler EA, Jadhav AP, Ducruet AF, Lawton MT, Albuquerque FC

Journal of neurointerventional surgery

Outcome comparison between interposition and "contactless" transposition microvascular decompression approaches for trigeminal neuralgia.

Lee AT, Morshed RA, Kondapavulur S, Caldwell DJ, Nichols N, Smith G, Wang A, Ward M, Waung MW, Winkler E, Chang EF

Journal of neurosurgery

Iatrogenic dural arteriovenous fistula formation as a rare complication of external ventricular drain placement: institutional review of 16 cases.

Kabir A, Shah S, Haddad AF, Amans MR, Cooke DL, Hetts SW, Narsinh KH, Savastano L, Winkler EA, Raper DMS

Journal of neurointerventional surgery

Arteriovenous shunts of the cervical spine: patient demographics, presentation, patterns of high-risk venous drainage, and updated classification.

Isikbay M, Caton MT, Mattay R, Han W, Cooke DL, Raper D, Winkler EA, Savastano L, Narsinh KH, Hetts SW, Amans MR

Journal of neurointerventional surgery

Extra-axial cavernous malformation of the cerebellopontine angle: illustrative case.

Hackett AM, Adereti CO, Hashem ES, Scherschinski L, Nico E, Eberle AT, Hartke JN, Fox BM, Winkler EA, Catapano JS, Lawton MT

Journal of neurosurgery. Case lessons

Identification of a T2-hyperintense Perivascular Space in Brain Arteriovenous Malformations.

Wälchli T, Bhatia KD, Guest W, Bisschop J, Olijnyk L, Kortman H, Constanthin PE, Nicholson P, Monnier PP, Kalyvas A, Winkler EA, Berhouma M, Krings T, Radovanovic I

In vivo (Athens, Greece)

Single-Cell Analysis in Cerebrovascular Research: Primed for Breakthroughs and Clinical Impact.

Albertson AJ, Winkler EA, Yang AC, Buckwalter MS, Dingman AL, Fan H, Herson PS, McCullough LD, Perez-Pinzon MA, Sansing LH, Sun D, Alkayed NJ

Natural history of dolichoectatic vertebrobasilar aneurysms: a multinational study.

Rezai Jahromi B, Dashti R, Ota N, Dabbagh Ohadi MA, Srinivasan V, Fiorella D, Kaukovalta H, Laakso A, Schwartz C, Kivisaari R, Zamotin V, Lindgren A, Koivisto T, Silva JM, Rustemi O, Kelahaara M, Jahromi BS, Killer-Oberpfalzer M, Potts MB, Noda K, Hecker C, Griessenauer CJ, Numminen J, Göhre F, Andrade-Barazante H, Hijazy F, Wessels L, Kalani MYS, Vajkoczy P, Spetzler RF, Jääskeläinen JE, Kawashima A, Winkler E, Tähtinen O, Latini R, Meessen J, Tanikawa R, Lawton MT, Niemelä M

Journal of neurosurgery

Posterior Inferior Cerebellar Artery Double Reimplantation Bypass for Treatment of a Dolichoectatic Posterior Inferior Cerebellar Artery Aneurysm: A Technical Report.

Hackett AM, Adereti CO, Nico E, Scherschinski L, Pace ML, Eberle AT, Malnik SL, Hartke JN, Fox BM, Winkler EA, Catapano JS, Lawton MT

Neurosurgery practice

Evaluation of ChatGPT in knowledge of newly evolving neurosurgery: middle meningeal artery embolization for subdural hematoma management.

Koester SW, Catapano JS, Hartke JN, Rudy RF, Cole TS, Naik A, Winkler EA, Graffeo CS, Srinivasan VM, Jadhav AP, Ducruet AF, Lawton MT, Albuquerque FC

Journal of neurointerventional surgery

Supply cost bundling in acute ischemic stroke treatment.

Koester SW, Catapano JS, Hoglund BK, Hartke JN, Naik A, Nico E, Hackett AM, Winkler EA, Lawton MT, Ducruet AF, Albuquerque FC, Jadhav AP

Journal of neurointerventional surgery

Predictors of Neurological Outcomes in Patients with Poor Glasgow Coma Scale Scores 1 Week After Aneurysmal Subarachnoid Hemorrhage.

Koester SW, Catapano JS, Hoglund BK, Rhodenhiser EG, Hartke JN, Rudy RF, Winkler EA, Jha RM, Jadhav AP, Ducruet AF, Albuquerque FC, Lawton MT

World neurosurgery

A taxonomy for cerebellar cavernous malformations: subtypes of cerebellar lesions.

Scherschinski L, Eberle AT, Saggi S, Jensen KN, Morshed RA, Winkler EA, Catapano JS, Graffeo CS, VanBrabant D, Lawrence PM, Lawton MT

Journal of neurosurgery

A single-cell atlas deconstructs heterogeneity across multiple models in murine traumatic brain injury and identifies novel cell-specific targets.

Jha RM, Rajasundaram D, Sneiderman C, Schlegel BT, O'Brien C, Xiong Z, Janesko-Feldman K, Trivedi R, Vagni V, Zusman BE, Catapano JS, Eberle A, Desai SM, Jadhav AP, Mihaljevic S, Miller M, Raikwar S, Rani A, Rulney J, Shahjouie S, Raphael I, Kumar A, Phuah CL, Winkler EA, Simon DW, Kochanek PM, Kohanbash G

Arteriovenous malformations in the cerebellopontine angle: assessment of the "backdoor resection" technique and microsurgical results in 38 patients.

Hanalioglu S, Graffeo CS, Srinivasan VM, Ibrahim S, Garcia JH, Koester SW, Aabedi AA, Catapano JS, Winkler EA, Lawton MT

Journal of neurosurgery

Assessing the Relationship between Surgical Timing and Postoperative Seizure Outcomes in Cavernoma-Related Epilepsy: A Single-Institution Retrospective Analysis of 63 Patients with a Review of the Literature.

Nico E, Adereti CO, Hackett AM, Bianconi A, Naik A, Eberle AT, Cifre Serra PJ, Koester SW, Malnik SL, Fox BM, Hartke JN, Winkler EA, Catapano JS, Lawton MT

Dolichoectatic Posterior Inferior Cerebellar Artery Aneurysm Treated With Excision and Posterior Inferior Cerebellar Artery Double Reimplantation Bypass: 2-Dimensional Operative Video.

Winkler EA, Catapano JS, Scherschinski L, Hackett AM, Lawton MT

Operative neurosurgery (Hagerstown, Md.)

Posterior Interhemispheric-Transtentorial Approach for Resection of an Arteriovenous Malformation of the Superior Medullary Velum and Fourth Ventricle: 2-Dimensional Operative Video.

Winkler EA, Scherschinski L, Catapano JS, DiDomenico JD, Hanalioglu S, Lawton MT

Operative neurosurgery (Hagerstown, Md.)

Middle meningeal artery embolization associated with reduced chronic subdural hematoma volume and midline shift in the acute postoperative period.

Catapano JS, Koester SW, Hanalioglu S, Farhadi DS, Naik A, Hartke JN, Tunc O, Winkler EA, Chang SW, Lawton MT, Jadhav AP, Ducruet AF, Albuquerque FC

Journal of neurointerventional surgery

Racial and Socioeconomic Status among a Patient Population Presenting with Aneurysmal Subarachnoid Hemorrhage versus Unruptured Intracranial Aneurysm: A Single-Center Study.

Hackett AM, Adereti CO, Walker AP, Nico E, Scherschinski L, Rhodenhiser EG, Eberle AT, Naik A, Giraldo JP, Hartke JN, Rahmani R, Winkler EA, Catapano JS, Lawton MT

ESMO expert consensus statements on the screening and management of financial toxicity in patients with cancer.

Carrera PM, Curigliano G, Santini D, Sharp L, Chan RJ, Pisu M, Perrone F, Karjalainen S, Numico G, Cherny N, Winkler E, Amador ML, Fitch M, Lawler M, Meunier F, Khera N, Pentheroudakis G, Trapani D, Ripamonti CI

Far Lateral Approach and Occipital Artery to Posterior Inferior Cerebellar Artery Bypass With Staged Flow Diversion for Treatment of De Novo Vertebrobasilar Junction Aneurysm: 2-Dimensional Operative Video.

Graffeo CS, Srinivasan VM, Scherschinski L, Winkler EA, Baranoski JF, Albuquerque FC, Lawton MT

Operative neurosurgery (Hagerstown, Md.)

Strategies to Improve Drug Delivery Across the Blood-Brain Barrier for Glioblastoma.

Narsinh KH, Perez E, Haddad AF, Young JS, Savastano L, Villanueva-Meyer JE, Winkler E, de Groot J

Current neurology and neuroscience reports

Retraction Note: Pericyte loss influences Alzheimer-like neurodegeneration in mice.

Sagare AP, Bell RD, Zhao Z, Ma Q, Winkler EA, Ramanathan A, Zlokovic BV

Nature communications

Microsurgical Resection of Brainstem Cavernous Malformations in Older Adults: A Multicenter, 30-Year Experience.

Catapano JS, Koester SW, Rumalla K, Lamorie-Foote K, Winkler EA, Benner D, Scherschinski L, Baranoski JF, Cole TS, Rudy RF, Graffeo CS, Srinivasan VM, Spetzler RF, Lawton MT

Endovascular biopsy in neurointerventional surgery: A systematic review.

Shekhtman O, Sioutas GS, Piavchenko G, Bhalla S, Cooke DL, Winkler E, Burkhardt JK, Srinivasan VM

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences

Flow diversion for basilar quadrifurcation aneurysms.

Srinivasan VM, Jubran JH, Stonnington HO, Catapano JS, Scherschinski L, Hendricks BK, Winkler EA, Rudy RF, Nguyen BA, Dabrowski SJ, Jadhav AP, Ducruet AF, Albuquerque FC

Journal of neurointerventional surgery

Sex differences in patients with and without high-risk factors associated with aneurysmal subarachnoid hemorrhage.

Catapano JS, Winkler EA, Rudy RF, Graffeo CS, Koester SW, Srinivasan VM, Cole TS, Baranoski JF, Scherschinski L, Jha RM, Jadhav AP, Ducruet AF, Albuquerque FC, Lawton MT

Acta neurochirurgica

Dural arteriovenous fistulas are not observed to convert to a higher grade after partial embolization.

Walker E, Srienc A, Lew D, Guniganti R, Lanzino G, Brinjikji W, Hayakawa M, Samaniego EA, Derdeyn CP, Du R, Lai R, Sheehan JP, Starke RM, Abla A, Abdelsalam A, Gross B, Albuquerque F, Lawton MT, Kim LJ, Levitt M, Amin-Hanjani S, Alaraj A, Winkler E, Fox WC, Polifka A, Hall S, Bulters D, Durnford A, Satomi J, Tada Y, van Dijk JMC, Potgieser ARE, Chen CJ, Becerril-Gaitan A, Osbun JW, Zipfel GJ

Neurosurgical focus

Modafinil Therapy and Mental Status Following Aneurysmal Subarachnoid Hemorrhage: Comprehensive Stroke Center Analysis.

Koester SW, Rumalla K, Catapano JS, Sorkhi SR, Mahadevan V, Devine GP, Naik A, Winkler EA, Rudy RF, Baranoski JF, Cole TS, Graffeo CS, Srinivasan VM, Jha RM, Jadhav AP, Ducruet AF, Albuquerque FC, Lawton MT

World neurosurgery

The VEBAS score: a practical scoring system for intracranial dural arteriovenous fistula obliteration.

Becerril-Gaitan A, Ding D, Ironside N, Buell TJ, Kansagra AP, Lanzino G, Brinjikji W, Kim L, Levitt MR, Abecassis IJ, Bulters D, Durnford A, Fox WC, Blackburn S, Chen PR, Polifka AJ, Laurent D, Gross B, Hayakawa M, Derdeyn C, Amin-Hanjani S, Alaraj A, van Dijk JMC, Potgieser ARE, Starke RM, Peterson EC, Satomi J, Tada Y, Abla AA, Winkler EA, Du R, Lai PMR, Zipfel GJ, Chen CJ, Sheehan JP, CONDOR investigators

Journal of neurointerventional surgery

Hematologic and Inflammatory Predictors of Outcome in Patients with Brain Arteriovenous Malformations.

Koester SW, Hoglund BK, Ciobanu-Caraus O, Hartke JN, Pacult MA, Winkler EA, Catapano JS, Lawton MT

World neurosurgery

Author Correction: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.

Zhao Z, Sagare AP, Ma Q, Halliday MR, Kong P, Kisler K, Winkler EA, Ramanathan A, Kanekiyo T, Bu G, Owens NC, Rege SV, Si G, Ahuja A, Zhu D, Miller CA, Schneider JA, Maeda M, Maeda T, Sugawara T, Ichida JK, Zlokovic BV

Nature neuroscience

Optimal PHASES Scoring for Risk Stratification of Surgically Treated Unruptured Aneurysms.

Koester SW, Rhodenhiser EG, Dabrowski SJ, Scherschinski L, Hartke JN, Naik A, Karahalios K, Nico E, Hackett AM, Ciobanu-Caraus O, Lopez Lopez LB, Winkler EA, Catapano JS, Lawton MT

World neurosurgery

Dural Arteriovenous Fistulas With Cognitive Impairment: Angiographic Characteristics and Treatment Outcomes.

Sanchez S, Wendt L, Hayakawa M, Chen CJ, Sheehan JP, Kim LJ, Abecassis IJ, Levitt MR, Meyer RM, Guniganti R, Kansagra AP, Lanzino G, Giordan E, Brinjikji W, Bulters DO, Durnford A, Fox WC, Smith J, Polifka AJ, Gross B, Amin-Hanjani S, Alaraj A, Kwasnicki A, Starke RM, Chen SH, van Dijk JMC, Potgieser ARE, Satomi J, Tada Y, Phelps R, Abla A, Winkler E, Du R, Rosalind Lai PM, Ortega-Gutierrez S, Zipfel GJ, Derdeyn C, Samaniego EA

Transcallosal-Transchoroidal Fissure Approach for Midbrain and Thalamic Cavernous Malformations: 2-Dimensional Operative Video.

Winkler EA, Lawton MT

Operative neurosurgery (Hagerstown, Md.)

A taxonomy for deep cerebral cavernous malformations: subtypes of basal ganglia lesions.

Catapano JS, Rumalla K, Srinivasan VM, Winkler EA, Benner D, Lawrence PM, Larson Keil K, Lawton MT

Journal of neurosurgery

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging.

Bell RD, Winkler EA, Sagare AP, Singh I, LaRue B, Deane R, Zlokovic BV

Author Correction: Pericyte loss influences Alzheimer-like neurodegeneration in mice.

Sagare AP, Bell RD, Zhao Z, Ma Q, Winkler EA, Ramanathan A, Zlokovic BV

Nature communications

Thoracic laminectomy and midline myelotomy for resection of a spinal ependymoma.

Scherschinski L, Winkler EA, Furey CG, Gooldy TC, Catapano JS, Lawton MT

Neurosurgical focus: Video

Infragalenic triangle as a gateway to dorsal midbrain and posteromedial thalamic lesions: descriptive and quantitative analysis of microsurgical anatomy.

Hanalioglu S, Gurses ME, Mignucci-Jiménez G, González-Romo NI, Winkler EA, Preul MC, Lawton MT

Journal of neurosurgery

Mortality After Microsurgical Treatment of Unruptured Intracranial Aneurysms in the Modern Era.

Catapano JS, Koester SW, Rhodenhiser EG, Scherschinski L, Karahalios K, Hoglund BK, Winkler EA, Hartke JN, Ciobanu-Caraus O, Naik A, Lopez Lopez LB, Rulney JD, Spetzler RF, Lawton MT

World neurosurgery

Transvenous Embolization of Dural Arteriovenous Fistulas Through the Galenic (Deep Venous) System: Multicenter Case Series and Meta-Analysis.

Srinivasan VM, Karahalios K, Colasurdo M, Rhodenheiser E, Scherschinski L, Lazaro TT, Cortez G, Gross BA, Kühn AL, Puri A, Winkler EA, Catapano JS, Akamatsu Y, Thomas A, Hanel RA, Wakhloo A, Jadhav AP, Ducruet AF, Albuquerque FC, Kan P

Operative neurosurgery (Hagerstown, Md.)

Endovascular Embolization of Basilar Artery Fenestration Aneurysms: A 21-Year Institutional Case Series.

Srinivasan VM, Singh R, Karahalios K, Scherschinski L, Essibayi MA, Catapano JS, Winkler EA, Jadhav AP, Ducruet AF, Albuquerque FC

Operative neurosurgery (Hagerstown, Md.)

A cross-species proteomic map reveals neoteny of human synapse development.

Wang L, Pang K, Zhou L, Cebrián-Silla A, González-Granero S, Wang S, Bi Q, White ML, Ho B, Li J, Li T, Perez Y, Huang EJ, Winkler EA, Paredes MF, Kovner R, Sestan N, Pollen AA, Liu P, Li J, Piao X, García-Verdugo JM, Alvarez-Buylla A, Liu Z, Kriegstein AR

Occipital Artery to Middle Cerebral Artery Direct Bypass: A Salvage Revascularization Technique for Ischemic Moyamoya Disease.

Baranoski JF, Catapano JS, Garcia JH, Cole TS, Winkler EA, Rudy RF, Rutledge C, Srinivasan VM, Graffeo CS, Lawton MT, Wanebo JE

World neurosurgery

Early Treatment of Ruptured Cerebral Arteriovenous Malformations: Analysis of Neurological Outcomes and Health Care Costs.

Baranoski JF, Koester SW, Catapano JS, Garcia JH, Pacult MA, Hoglund BK, Dabrowski SJ, Benner D, Winkler EA, Cole TS, Rutledge C, Srinivasan VM, Graffeo CS, Ducruet AF, Albuquerque FC, Lawton MT

Editorial: Cerebral and spinal vascular malformations: from bench to bedside.

Ma L, Yang W, Winkler E, Burkhardt JK, Su H

Frontiers in neurology

A Review of Preoperative Embolization Effectiveness in Patients With Arteriovenous Malformations.

Catapano JS, Koester SW, Rumalla K, Rangel IC, Stonnington HO, Singh R, Memon A, Kimata AR, Winkler EA, Baranoski JF, Cole TS, Graffeo CS, Srinivasan VM, Jadhav AP, Ducruet AF, Albuquerque FC, Lawton MT

Endovascular Treatment of Cerebrovascular Lesions Using Nickel- or Nitinol-Containing Devices in Patients with Nickel Allergies.

Baranoski JF, Catapano JS, Rutledge C, Cole TS, Majmundar N, Winkler EA, Srinivasan VM, Jadhav AP, Ducruet AF, Albuquerque FC

AJNR. American journal of neuroradiology

Factors Associated with Unfavorable Clinical Presentations in Patients with Ruptured BrainArteriovenous Malformations.

Garcia JH, Carrete L, Rutledge WC, Raygor KP, Winkler EA, Pereira MP, Nelson J, Kim H, Cooke DL, Hetts SW, Lawton MT, Abla AA

World neurosurgery

Cerebrospinal Fluid Biomarkers for Diagnosis and the Prognostication of Acute Ischemic Stroke: A Systematic Review.

Naik A, Adeleye O, Koester SW, Winkler EA, Hartke JN, Karahalios K, Mihaljevic S, Rani A, Raikwar S, Rulney JD, Desai SM, Scherschinski L, Ducruet AF, Albuquerque FC, Lawton MT, Catapano JS, Jadhav AP, Jha RM

International journal of molecular sciences

Double-Interposition Bypass: Technical Case Report of a Novel Intraoperative Bypass Salvage Technique.

Graffeo CS, Srinivasan VM, Winkler EA, Lawton MT

Operative neurosurgery (Hagerstown, Md.)

Association Between Neurological Outcomes and Timing of Physical Therapy Initiation Among Patients Treated for Aneurysmal Subarachnoid Hemorrhage: A Propensity-Adjusted Analysis.

Catapano JS, Koester SW, Rumalla K, Dabrowski SJ, Winkler EA, Rudy RF, Cole TS, Baranoski JF, Graffeo CS, Srinivasan VM, Jha RM, Jadhav AP, Ducruet AF, Albuquerque FC, Lawton MT

Neurosurgery practice

Association between external ventricular drain removal or replacement and prophylactic anticoagulation in patients with aneurysmal subarachnoid hemorrhage: a propensity-adjusted analysis.

Catapano JS, Koester SW, Parikh PP, Rumalla K, Stonnington HO, Singh R, Winkler EA, Graffeo CS, Rudy RF, Srinivasan VM, Jha RM, Jadhav AP, Albuquerque FC, Lawton MT, Ducruet AF

Acta neurochirurgica

Outcomes in Patients with Aneurysmal Subarachnoid Hemorrhage Receiving Sulfonylureas: A Propensity-Adjusted Analysis.

Catapano JS, Koester SW, Bond KM, Srinivasan VM, Farhadi DS, Rumalla K, Cole TS, Baranoski JF, Winkler EA, Graffeo CS, Muñoz-Casabella A, Jadhav AP, Ducruet AF, Albuquerque FC, Lawton MT, Jha RM

World neurosurgery

Localized conditional induction of brain arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia.

Scherschinski L, Han C, Kim YH, Winkler EA, Catapano JS, Schriber TD, Vajkoczy P, Lawton MT, Oh SP

A taxonomy for deep cerebral cavernous malformations: subtypes of thalamic lesions.

Catapano JS, Rumalla K, Srinivasan VM, Benner D, Winkler EA, Lawrence PM, Larson Keil K, Lawton MT

Journal of neurosurgery

Cost-Effectiveness of Forgoing Postoperative Catheter Angiography After Microsurgical Occlusion of Spinal Dorsal Intradural Arteriovenous Fistulas.

Scherschinski L, Karahalios K, Srinivasan VM, Catapano JS, Jubran JH, Benner D, Rumalla K, Winkler EA, Graffeo CS, Lawton MT

World neurosurgery

Author Correction: Apolipoprotein E controls cerebrovascular integrity via cyclophilin A.

Bell RD, Winkler EA, Singh I, Sagare AP, Deane R, Wu Z, Holtzman DM, Betsholtz C, Armulik A, Sallstrom J, Berk BC, Zlokovic BV

A comprehensive assessment of self-reported symptoms among patients harboring an unruptured intracranial aneurysm.

Hackett AM, Koester SW, Rhodenhiser EG, Scherschinski L, Rulney JD, Naik A, Nico E, Eberle AT, Hartke JN, Fox BM, Winkler EA, Catapano JS, Lawton MT

Frontiers in surgery

Approach Selection Strategies for Repeat Resection of Brain Cavernous Malformations: Cohort Study.

Graffeo CS, Scherschinski L, Benner D, Devia DA, Thomas G, Koester SW, Catapano JS, Winkler EA, Srinivasan VM, Lawton MT

Operative neurosurgery (Hagerstown, Md.)

A comparison of incidental and symptomatic unruptured brain arteriovenous malformations in children.

Lu AY, Winkler EA, Garcia JH, Raygor KP, Fullerton HJ, Fox CK, Kim H, Auguste KI, Sun PP, Hetts SW, Lawton MT, Abla AA, Gupta N

Journal of neurosurgery. Pediatrics

Socioeconomic Drivers of Outcomes After Aneurysmal Subarachnoid Hemorrhage Treatment at a Large Comprehensive Stroke Center.

Rumalla K, Catapano JS, Mahadevan V, Sorkhi SR, Koester SW, Winkler EA, Graffeo CS, Srinivasan VM, Jha RM, Jadhav AP, Ducruet AF, Albuquerque FC, Lawton MT

World neurosurgery

You Take the Low Road: Differential Outcomes After Tangential and Transcortical Approaches to Medial Temporal Brain Arteriovenous Malformations.

Scherschinski L, Srinivasan VM, Karahalios K, Garcia JH, Koester SW, Jubran JH, Benner D, Winkler EA, Catapano JS, Labib MA, Graffeo CS, Lawton MT

World neurosurgery

Propensity-adjusted analysis of ultra-early aneurysmal subarachnoid hemorrhage treatment and patient outcomes.

Koester SW, Catapano JS, Rhodenhiser EG, Rudy RF, Winkler EA, Benner D, Cole TS, Baranoski JF, Srinivasan VM, Graffeo CS, Jha RM, Jadhav AP, Ducruet AF, Albuquerque FC, Lawton MT

Acta neurochirurgica

Surgical management of Eagle's syndrome causing neurovascular compression.

Singh R, Hartke JN, Catapano JS, Scherschinski L, Rahmani R, Srinivasan VM, Winkler EA, Graffeo CS, Lawton MT

Clinical neurology and neurosurgery

Incidence and Prediction of Chronic Depression Following Aneurysmal Subarachnoid Hemorrhage: A Single-Center 17-Year Experience.

Catapano JS, Rumalla K, Koester SW, Winkler EA, Rudy RF, Cole TS, Baranoski JF, Graffeo CS, Srinivasan VM, Jha RM, Jadhav AP, Ducruet AF, Albuquerque FC, Lawton MT

World neurosurgery

Intraventricular Tissue Plasminogen Activator and Shunt Dependency in Aneurysmal Subarachnoid Hemorrhage.

Pacult MA, Catapano JS, Rumalla K, Winkler EA, Graffeo CS, Srinivasan VM, Jadhav AP, Ducruet AF, Albuquerque FC, Lawton MT

World neurosurgery

Safety of brainstem safe entry zones: comparison of microsurgical outcomes associated with superficial, exophytic, and deep brainstem cavernous malformations.

Catapano JS, Benner D, Rhodenhiser EG, Rumalla K, Graffeo CS, Srinivasan VM, Winkler EA, Lawton MT

Journal of neurosurgery

Analysis of the Weekend Effect at a High-Volume Center for the Treatment of Intracranial Aneurysms.

Koester SW, Catapano JS, Rumalla K, Srinivasan VM, Rhodenhiser EG, Hartke JN, Benner D, Winkler EA, Cole TS, Baranoski JF, Jadhav AP, Ducruet AF, Albuquerque FC, Lawton MT

World neurosurgery

Direct puncture of the superior ophthalmic vein for carotid cavernous fistulas: a 21-year experience.

Catapano JS, Srinivasan VM, De La Peña NM, Singh R, Cole TS, Wilkinson DA, Baranoski JF, Rutledge C, Pacult MA, Winkler EA, Jadhav AP, Ducruet AF, Albuquerque FC

Journal of neurointerventional surgery

Challenging access during flow diversion treatment of a giant cavernous ICA aneurysm.

Srinivasan VM, Hartke JN, Catapano JS, Winkler EA, Jadhav AP, Albuquerque FC, Ducruet AF

Neurosurgical focus: Video

Retained radial catheters associated with variant radial anatomy in neurointerventional procedures.

Catapano JS, Winkler EA, Srinivasan VM, Dishion EL, Rutledge C, Baranoski JF, Cole TS, Rudy RF, Rumalla K, Zomaya MP, Jadhav AP, Ducruet AF, Albuquerque FC

Journal of neurointerventional surgery

Liver Cirrhosis and Inpatient Mortality in Aneurysmal Subarachnoid Hemorrhage: A Propensity-Adjusted Analysis.

Catapano JS, Lee KE, Rumalla K, Srinivasan VM, Cole TS, Baranoski JF, Winkler EA, Graffeo CS, Alabdly M, Jha RM, Jadhav AP, Ducruet AF, Albuquerque FC, Lawton MT

World neurosurgery

Health Care Expenditures Associated with Delayed Cerebral Ischemia Following Subarachnoid Hemorrhage: A Propensity-Adjusted Analysis.

Koester SW, Catapano JS, Rumalla K, Dabrowski SJ, Benner D, Winkler EA, Cole TS, Baranoski JF, Srinivasan VM, Graffeo CS, Jha RM, Jadhav AP, Ducruet AF, Albuquerque FC, Lawton MT

World neurosurgery

Natural history, angiographic presentation and outcomes of anterior cranial fossa dural arteriovenous fistulas.

Sanchez S, Raghuram A, Wendt L, Hayakawa M, Chen CJ, Sheehan JP, Kim LJ, Abecassis IJ, Levitt MR, Meyer RM, Guniganti R, Kansagra AP, Lanzino G, Giordan E, Brinjikji W, Bulters DO, Durnford A, Fox WC, Smith J, Polifka AJ, Gross B, Amin-Hanjani S, Alaraj A, Kwasnicki A, Starke RM, Chen SH, van Dijk JMC, Potgieser ARE, Satomi J, Tada Y, Phelps R, Abla A, Winkler E, Du R, Lai PMR, Zipfel GJ, Derdeyn C, Samaniego EA

Journal of neurointerventional surgery

Tropism of SARS-CoV-2 for human cortical astrocytes.

Andrews MG, Mukhtar T, Eze UC, Simoneau CR, Ross J, Parikshak N, Wang S, Zhou L, Koontz M, Velmeshev D, Siebert CV, Gemenes KM, Tabata T, Perez Y, Wang L, Mostajo-Radji MA, de Majo M, Donohue KC, Shin D, Salma J, Pollen AA, Nowakowski TJ, Ullian E, Kumar GR, Winkler EA, Crouch EE, Ott M, Kriegstein AR

Proceedings of the National Academy of Sciences of the United States of America

Emerging pathogenic mechanisms in human brain arteriovenous malformations: a contemporary review in the multiomics era.

Winkler EA, Pacult MA, Catapano JS, Scherschinski L, Srinivasan VM, Graffeo CS, Oh SP, Lawton MT

Neurosurgical focus

Intraoperative Angiogram Using C-Arm Fluoroscopy and Direct Common Carotid Artery Puncture During Surgical Treatment of Paraclinoid Aneurysms.

Budohoski KP, Raygor K, Tonetti DA, Narsinh KH, Winkler EA, Dowd C, Abla AA

World neurosurgery

Machine learning for predicting hemorrhage in pediatric patients with brain arteriovenous malformation.

Saggi S, Winkler EA, Ammanuel SG, Morshed RA, Garcia JH, Young JS, Semonche A, Fullerton HJ, Kim H, Cooke DL, Hetts SW, Abla A, Lawton MT, Gupta N

Journal of neurosurgery. Pediatrics

Middle Meningeal Artery Embolization for Chronic Subdural Hematomas Is Efficacious and Cost-Effective.

Pacult MA, Catapano JS, Koester SW, Winkler EA, Srinivasan VM, Jadhav AP, Ducruet AF, Lawton MT, Albuquerque FC

World neurosurgery

A single-cell atlas of the normal and malformed human brain vasculature.

Winkler EA, Kim CN, Ross JM, Garcia JH, Gil E, Oh I, Chen LQ, Wu D, Catapano JS, Raygor K, Narsinh K, Kim H, Weinsheimer S, Cooke DL, Walcott BP, Lawton MT, Gupta N, Zlokovic BV, Chang EF, Abla AA, Lim DA, Nowakowski TJ

Science (New York, N.Y.)

Electroencephalography for detection of vasospasm and delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage: a retrospective analysis and systematic review.

Scherschinski L, Catapano JS, Karahalios K, Koester SW, Benner D, Winkler EA, Graffeo CS, Srinivasan VM, Jha RM, Jadhav AP, Ducruet AF, Albuquerque FC, Lawton MT

Neurosurgical focus

Validation of the Ruptured Arteriovenous Malformation Grading Scale in a pediatric cohort.

Garcia JH, Rutledge C, Winkler EA, Carrete L, Morshed RA, Lu AY, Saggi S, Fox CK, Fullerton HJ, Kim H, Cooke DL, Hetts SW, Lawton MT, Gupta N, Abla AA

Journal of neurosurgery. Pediatrics

Endoluminal Biopsy for Molecular Profiling of Human Brain Vascular Malformations.

Winkler E, Wu D, Gil E, McCoy D, Narsinh K, Sun Z, Mueller K, Ross J, Kim H, Weinsheimer S, Berger M, Nowakowski T, Lim D, Abla A, Cooke D

Role and responsibility of oncologists in assisted suicide. Practice and views among members of the German Society of Haematology and Medical Oncology.

Schildmann J, Junghanss C, Oldenburg M, Schuler U, Trümper L, Wörmann B, Winkler E

Total 1-year hospital cost of middle meningeal artery embolization compared to surgery for chronic subdural hematomas: a propensity-adjusted analysis.

Catapano JS, Koester SW, Srinivasan VM, Rumalla K, Baranoski JF, Rutledge C, Cole TS, Winkler EA, Lawton MT, Jadhav AP, Ducruet AF, Albuquerque FC

Journal of neurointerventional surgery

Association of Posttraumatic Epilepsy With 1-Year Outcomes After Traumatic Brain Injury.

Burke J, Gugger J, Ding K, Kim JA, Foreman B, Yue JK, Puccio AM, Yuh EL, Sun X, Rabinowitz M, Vassar MJ, Taylor SR, Winkler EA, Deng H, McCrea M, Stein MB, Robertson CS, Levin HS, Dikmen S, Temkin NR, Barber J, Giacino JT, Mukherjee P, Wang KKW, Okonkwo DO, Markowitz AJ, Jain S, Lowenstein D, Manley GT, Diaz-Arrastia R, TRACK-TBI Investigators, Badjatia N, Duhaime AC, Feeser VR, Gaudette E, Gopinath S, Keene CD, Korley FK, Madden C, Merchant R, Schnyer D, Zafonte R

JAMA network open

Endovascular Biopsy of Vertebrobasilar Aneurysm in Patient With Polyarteritis Nodosa.

Narsinh KH, Narsinh K, McCoy DB, Sun Z, Halabi C, Meisel K, Tihan T, Chaganti K, Amans MR, Halbach VV, Higashida RT, Hetts SW, Dowd CF, Winkler EA, Abla AA, Nowakowski TJ, Cooke DL

Frontiers in neurology

Sulfonylurea Receptor 1 in Central Nervous System Injury: An Updated Review.

Jha RM, Rani A, Desai SM, Raikwar S, Mihaljevic S, Munoz-Casabella A, Kochanek PM, Catapano J, Winkler E, Citerio G, Hemphill JC, Kimberly WT, Narayan R, Sahuquillo J, Sheth KN, Simard JM

International journal of molecular sciences

Factors associated with seizures at initial presentation in pediatric patients with cerebral arteriovenous malformations.

Garcia JH, Winkler EA, Morshed RA, Lu A, Ammanuel SG, Saggi S, Wang EJ, Braunstein S, Fox CK, Fullerton HJ, Kim H, Cooke DL, Hetts SW, Lawton MT, Abla AA, Gupta N

Journal of neurosurgery. Pediatrics

Radial artery access anatomy: considerations for neuroendovascular procedures.

Narsinh KH, Mirza MH, Duvvuri M, Caton MT, Baker A, Winkler EA, Higashida RT, Halbach VV, Amans MR, Cooke DL, Hetts SW, Abla AA, Dowd CF

Journal of neurointerventional surgery

Radial artery access for neuroendovascular procedures: safety review and complications.

Narsinh KH, Mirza MH, Caton MT, Baker A, Winkler E, Higashida RT, Halbach VV, Amans MR, Cooke DL, Hetts SW, Abla AA, Dowd CF

Journal of neurointerventional surgery

Assessing the rate, natural history, and treatment trends of intracranial aneurysms in patients with intracranial dural arteriovenous fistulas: a Consortium for Dural Arteriovenous Fistula Outcomes Research (CONDOR) investigation.

Abecassis IJ, Meyer RM, Levitt MR, Sheehan JP, Chen CJ, Gross BA, Lockerman A, Fox WC, Brinjikji W, Lanzino G, Starke RM, Chen SH, Potgieser ARE, van Dijk JMC, Durnford A, Bulters D, Satomi J, Tada Y, Kwasnicki A, Amin-Hanjani S, Alaraj A, Samaniego EA, Hayakawa M, Derdeyn CP, Winkler E, Abla A, Lai PMR, Du R, Guniganti R, Kansagra AP, Zipfel GJ, Kim LJ, Consortium for Dural Arteriovenous Fistula Outcomes Research, CONDOR Collaborators

Journal of neurosurgery

Comparison of Outcomes following Primary and Repeat Resection of Craniopharyngioma.

Aabedi AA, Young JS, Phelps RRL, Winkler EA, McDermott MW, Theodosopoulos PV

Journal of neurological surgery. Part B, Skull base

Consortium for Dural Arteriovenous Fistula Outcomes Research (CONDOR): rationale, design, and initial characterization of patient cohort.

Guniganti R, Giordan E, Chen CJ, Abecassis IJ, Levitt MR, Durnford A, Smith J, Samaniego EA, Derdeyn CP, Kwasnicki A, Alaraj A, Potgieser ARE, Sur S, Chen SH, Tada Y, Winkler E, Phelps RRL, Lai PMR, Du R, Abla A, Satomi J, Starke RM, van Dijk JMC, Amin-Hanjani S, Hayakawa M, Gross BA, Fox WC, Bulters D, Kim LJ, Sheehan J, Lanzino G, Piccirillo JF, Kansagra AP, Zipfel GJ, Consortium for Dural Arteriovenous Fistula Outcomes Research, CONDOR Collaborators

Journal of neurosurgery

Dural arteriovenous fistulas without cortical venous drainage: presentation, treatment, and outcomes.

Samaniego EA, Roa JA, Hayakawa M, Chen CJ, Sheehan JP, Kim LJ, Abecassis IJ, Levitt MR, Guniganti R, Kansagra AP, Lanzino G, Giordan E, Brinjikji W, Bulters D, Durnford A, Fox WC, Polifka AJ, Gross BA, Amin-Hanjani S, Alaraj A, Kwasnicki A, Starke RM, Sur S, van Dijk JMC, Potgieser ARE, Satomi J, Tada Y, Abla A, Winkler E, Du R, Lai PMR, Zipfel GJ, Derdeyn CP, Consortium for Dural Arteriovenous Fistula Outcomes Research, CONDOR Collaborators

Journal of neurosurgery

Intervention for unruptured high-grade intracranial dural arteriovenous fistulas: a multicenter study.

Chen CJ, Buell TJ, Ding D, Guniganti R, Kansagra AP, Lanzino G, Giordan E, Kim LJ, Levitt MR, Abecassis IJ, Bulters D, Durnford A, Fox WC, Polifka AJ, Gross BA, Hayakawa M, Derdeyn CP, Samaniego EA, Amin-Hanjani S, Alaraj A, Kwasnicki A, van Dijk JMC, Potgieser ARE, Starke RM, Sur S, Satomi J, Tada Y, Abla AA, Winkler EA, Du R, Lai PMR, Zipfel GJ, Sheehan JP, Consortium for Dural Arteriovenous Fistula Outcomes Research, CONDOR Collaborators

Journal of neurosurgery

Recurrence after cure in cranial dural arteriovenous fistulas: a collaborative effort by the Consortium for Dural Arteriovenous Fistula Outcomes Research (CONDOR).

Abecassis IJ, Meyer RM, Levitt MR, Sheehan JP, Chen CJ, Gross BA, Smith J, Fox WC, Giordan E, Lanzino G, Starke RM, Sur S, Potgieser ARE, van Dijk JMC, Durnford A, Bulters D, Satomi J, Tada Y, Kwasnicki A, Amin-Hanjani S, Alaraj A, Samaniego EA, Hayakawa M, Derdeyn CP, Winkler E, Abla A, Lai PMR, Du R, Guniganti R, Kansagra AP, Zipfel GJ, Kim LJ, Consortium for Dural Arteriovenous Fistula Outcomes Research, CONDOR Collaborators

Journal of neurosurgery

Pediatric moyamoya MRI score: an imaging-based scale to predict outcomes in surgically treated pediatric patients with moyamoya.

Garcia JH, Morshed RA, Winkler EA, Li Y, Fox CK, Fullerton HJ, Rutledge C, Beniwal AS, Lawton MT, Abla AA, Gupta N, Hetts SW

Neurosurgical focus

Multiple Tumor-Associated Intracranial Aneurysms Adjacent to a Suprasellar Germ Cell Tumor: Case Report and Review of Literature.

Yue JK, Chang D, Oh T, Winkler EA, Lu AY, Hetts SW, Young EP, Reddy AT, Fox CK, Abla AA, Roland JL

Pediatric neurosurgery

Somatic mosaicism in the MAPK pathway in sporadic brain arteriovenous malformation and association with phenotype.

Gao S, Nelson J, Weinsheimer S, Winkler EA, Rutledge C, Abla AA, Gupta N, Shieh JT, Cooke DL, Hetts SW, Tihan T, Hess CP, Ko N, Walcott BP, McCulloch CE, Lawton MT, Su H, Pawlikowska L, Kim H

Journal of neurosurgery

Review of treatment and therapeutic targets in brain arteriovenous malformation.

Pan P, Weinsheimer S, Cooke D, Winkler E, Abla A, Kim H, Su H

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Sensitivity of the Unruptured Intracranial Aneurysm Treatment Score (UIATS) in the Elderly: Retrospective Analysis of Ruptured Aneurysms.

Rutledge C, Raper DMS, Jonzzon S, Raygor KP, Pereira MP, Winkler EA, Zhang L, Lawton MT, Abla AA

World neurosurgery

Elderly traumatic central cord syndrome in the USA: a review of management and outcomes.

Phelps RR, Yue JK, Tsolinas RE, Deng H, Rios J, Upadhyayula PS, Dalle Ore CL, Lee YM, Suen CG, Burke JF, Winkler EA, Dhall SS

Journal of neurosurgical sciences

Predictors of six-month inability to return to work in previously employed subjects after mild traumatic brain injury: A TRACK-TBI pilot study.

Yue JK, Phelps RR, Hemmerle DD, Upadhyayula PS, Winkler EA, Deng H, Chang D, Vassar MJ, Taylor SR, Schnyer DM, Lingsma HF, Puccio AM, Yuh EL, Mukherjee P, Huang MC, Ngwenya LB, Valadka AB, Markowitz AJ, Okonkwo DO, Manley GT, TRACK-TBI Investigators

Journal of concussion

Endovascular embolization versus surgical clipping in a single surgeon series of basilar artery aneurysms: a complementary approach in the endovascular era.

Winkler EA, Lee A, Yue JK, Raygor KP, Rutledge WC, Rubio RR, Josephson SA, Berger MS, Raper DMS, Abla AA

Acta neurochirurgica

Supracerebellar Infratentorial Infratrochlear Trans-Quadrangular Lobule Approach to Pontine Cavernous Malformations.

Rutledge C, Raper DMS, Rodriguez Rubio R, Winkler EA, Abla AA

Operative neurosurgery (Hagerstown, Md.)

High-Sensitivity C-Reactive Protein is a Prognostic Biomarker of Six-Month Disability after Traumatic Brain Injury: Results from the TRACK-TBI Study.

Xu LB, Yue JK, Korley F, Puccio AM, Yuh EL, Sun X, Rabinowitz M, Vassar MJ, Taylor SR, Winkler EA, Puffer RC, Deng H, McCrea M, Stein MB, Robertson CS, Levin HS, Dikmen S, Temkin NR, Giacino JT, Mukherjee P, Wang KKW, Okonkwo DO, Markowitz AJ, Jain S, Manley GT, Diaz-Arrastia R, TRACK-TBI Investigators

Journal of neurotrauma

Controversies and Advances in Adult Intracranial Bypass Surgery in 2020.

Raper DMS, Rutledge WC, Winkler EA, Meisel K, Callen AL, Cooke DL, Abla AA

Operative neurosurgery (Hagerstown, Md.)

The Expanding Cell Diversity of the Brain Vasculature.

Ross JM, Kim C, Allen D, Crouch EE, Narsinh K, Cooke DL, Abla AA, Nowakowski TJ, Winkler EA

Frontiers in physiology

Transcirculation approach for stent-assisted coiling of intracranial aneurysms: a multicenter study.

Mascitelli JR, Levitt MR, Griessenauer CJ, Kim LJ, Gross B, Abla A, Winkler E, Jankowitz B, Grandhi R, Goren O, Schirmer CM

Journal of neurointerventional surgery

Far-Lateral Transcondylar Approach to a Right Cervicomedullary Dural Arteriovenous Fistula of the Posterior Fossa.

Rubio RR, Chae R, Dubnicoff T, Winkler E, Abla AA

Journal of neurological surgery. Part B, Skull base

An Update on Medications for Brain Arteriovenous Malformations.

Raper DMS, Winkler EA, Rutledge WC, Cooke DL, Abla AA

Cerebrovascular complications of coccidioidomycosis meningitis: Case report and systematic review.

Phelps RRL, Lu AY, Lee AT, Yue JK, Winkler EA, Raygor KP, Oh T, Barkovich MJ, Hollander H

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Surgical selection and outcomes among elderly patients with brain arteriovenous malformations.

Burkhardt JK, Winkler EA, Catapano JS, Spetzler RF, Lawton MT

Neurosurgical focus

Definitive Treatment With Microsurgical Clipping After Recurrence and Rerupture of Coiled Anterior Cerebral Artery Aneurysms.

Raper DMS, Rutledge C, Winkler EA, Abla AA

Operative neurosurgery (Hagerstown, Md.)

Sideline Concussion Assessment: The Current State of the Art.

Yue JK, Phelps RRL, Chandra A, Winkler EA, Manley GT, Berger MS

Clinical outcomes after revascularization for pediatric moyamoya disease and syndrome: A single-center series.

Morshed RA, Abla AA, Murph D, Dao JM, Winkler EA, Burkhardt JK, Colao K, Hetts SW, Fullerton HJ, Lawton MT, Gupta N, Fox CK

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Letter to the editor: "Is the unruptured intracranial aneurysm treatment score (UIATS) sensitive enough to detect aneurysms at risk of rupture?"

Rutledge C, Raper DMS, Winkler EA, Abla AA

Neurosurgical review

Polytrauma Is Associated with Increased Three- and Six-Month Disability after Traumatic Brain Injury: A TRACK-TBI Pilot Study.

Yue JK, Satris GG, Dalle Ore CL, Huie JR, Deng H, Winkler EA, Lee YM, Vassar MJ, Taylor SR, Schnyer DM, Lingsma HF, Puccio AM, Yuh EL, Mukherjee P, Valadka AB, Ferguson AR, Markowitz AJ, Okonkwo DO, Manley GT

Neurotrauma reports

Early versus Delayed Microsurgical Clipping of Additional Unruptured Aneurysms in Patients with Aneurysmal Subarachnoid Hemorrhage.

Burkhardt JK, Winkler EA, Weller J, Lawton MT

World neurosurgery

Multicenter Postmarket Analysis of the Neuroform Atlas Stent for Stent-Assisted Coil Embolization of Intracranial Aneurysms.

Burkhardt JK, Srinivasan V, Srivatsan A, Albuquerque F, Ducruet AF, Hendricks B, Gross BA, Jankowitz BT, Thomas AJ, Ogilvy CS, Maragkos GA, Enriquez-Marulanda A, Crowley RW, Levitt MR, Kim LJ, Griessenauer CJ, Schirmer CM, Dalal S, Piper K, Mokin M, Winkler EA, Abla AA, McDougall C, Birnbaum L, Mascitelli J, Litao M, Tanweer O, Riina H, Johnson J, Chen S, Kan P

AJNR. American journal of neuroradiology

Transforming Research and Clinical Knowledge in Spinal Cord Injury (TRACK-SCI): an overview of initial enrollment and demographics.

Tsolinas RE, Burke JF, DiGiorgio AM, Thomas LH, Duong-Fernandez X, Harris MH, Yue JK, Winkler EA, Suen CG, Pascual LU, Ferguson AR, Huie JR, Pan JZ, Hemmerle DD, Singh V, Torres-Espin A, Omondi C, Kyritsis N, Haefeli J, Weinstein PR, de Almeida Neto CA, Kuo YH, Taggard D, Talbott JF, Whetstone WD, Manley GT, Bresnahan JC, Beattie MS, Dhall SS

Neurosurgical focus

Small Aneurysms with Low PHASES Scores Account for Most Subarachnoid Hemorrhage Cases.

Rutledge C, Jonzzon S, Winkler EA, Raper D, Lawton MT, Abla AA

World neurosurgery

Interhemispheric Surgical Approaches for Ruptured Intraventricular Arteriovenous Malformation-Associated Aneurysms: Technical Report and Case Series.

Raper DMS, Winkler EA, Rutledge WC, Hetts SW, Abla AA

World neurosurgery

Bringing high-grade arteriovenous malformations under control: clinical outcomes following multimodality treatment in children.

Winkler EA, Lu A, Morshed RA, Yue JK, Rutledge WC, Burkhardt JK, Patel AB, Ammanuel SG, Braunstein S, Fox CK, Fullerton HJ, Kim H, Cooke D, Hetts SW, Lawton MT, Abla AA, Gupta N

Journal of neurosurgery. Pediatrics

High-Flow Vascular Malformations in Children.

Morshed RA, Winkler EA, Kim H, Braunstein S, Cooke DL, Hetts SW, Abla AA, Fullerton HJ, Gupta N

Seminars in neurology

Substance use on admission toxicology screen is associated with peri-injury factors and six-month outcome after traumatic brain injury: A TRACK-TBI Pilot study.

Yue JK, Phelps RRL, Winkler EA, Deng H, Upadhyayula PS, Vassar MJ, Madhok DY, Schnyer DM, Puccio AM, Lingsma HF, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Manley GT, TRACK-TBI Investigators

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Concurrent presentation of brain arteriovenous malformation, peripheral arteriovenous malformation, and cerebellar astrocytoma: Case report.

Gautam A, Sun Z, Winkler E, Su H, McCalmont TH, Kim H, Tihan T, Hoffman WY, Dowd CF, Frieden IJ, Cooke DL

Interdisciplinary neurosurgery : Advanced techniques and case management

Commentary: Post-treatment Antiplatelet Therapy Reduces Risk for Delayed Cerebral Ischemia Due to Aneurysmal Subarachnoid Hemorrhage.

Raygor KP, Winkler EA, Rutledge WC, Rubio RR, Abla AA

Cost determinants in management of brain arteriovenous malformations.

Rutledge C, Nelson J, Lu A, Nisson P, Jonzzon S, Winkler EA, Cooke D, Abla AA, Lawton MT, Kim H

Acta neurochirurgica

Spontaneous Perforation of Anterior Choroidal Artery with Resultant Pseudoaneurysm Formation: Unusual Cause of Subarachnoid Hemorrhage.

Raper DMS, Rutledge WC, Winkler E, Abla AA

World neurosurgery

Y-Stent Technique for Treatment of Wide-Necked Posterior Communicating Artery Aneurysm Associated with Fetal Posterior Cerebral Artery: Technical Report.

Raper DMS, Rutledge WC, Winkler EA, Abla AA

World neurosurgery

Microsurgical Clipping of Anterior Choroidal Artery Aneurysms: A Systematic Approach to Reducing Ischemic Complications in an Experience with 146 Patients.

Winkler EA, Lu A, Burkhardt JK, Rutledge WC, Yue JK, Birk HS, Alotaibi N, Choudhri O, Lawton MT

Operative neurosurgery (Hagerstown, Md.)

Clinical Implementation of Novel Spinal Cord Perfusion Pressure Protocol in Acute Traumatic Spinal Cord Injury at U.S. Level I Trauma Center: TRACK-SCI Study.

Yue JK, Hemmerle DD, Winkler EA, Thomas LH, Fernandez XD, Kyritsis N, Pan JZ, Pascual LU, Singh V, Weinstein PR, Talbott JF, Huie JR, Ferguson AR, Whetstone WD, Manley GT, Beattie MS, Bresnahan JC, Mummaneni PV, Dhall SS

World neurosurgery

An Anatomical Feasibility Study for Revascularization of the Ophthalmic Artery. Part II: Intraorbital Segment.

Rubio RR, Vigo V, Gandhi S, Tabani H, Meybodi AT, Winkler EA, Abla AA, Lawton MT, Benet A

World neurosurgery

Pediatric firearm-related traumatic brain injury in United States trauma centers.

Deng H, Yue JK, Winkler EA, Dhall SS, Manley GT, Tarapore PE

Journal of neurosurgery. Pediatrics

Supracerebellar Approach to Radiation-Induced Giant Capillary Telangiectasia Within Juvenile Pilocytic Astrocytoma of Upper Brainstem.

Rubio RR, Chae R, Khare A, Dubnicoff T, Winkler E, Sloan E, Bollen AW, Berger MS, Abla AA

World neurosurgery

Association between plasma GFAP concentrations and MRI abnormalities in patients with CT-negative traumatic brain injury in the TRACK-TBI cohort: a prospective multicentre study.

Yue JK, Yuh EL, Korley FK, Winkler EA, Sun X, Puffer RC, Deng H, Choy W, Chandra A, Taylor SR, Ferguson AR, Huie JR, Rabinowitz M, Puccio AM, Mukherjee P, Vassar MJ, Wang KKW, Diaz-Arrastia R, Okonkwo DO, Jain S, Manley GT, TRACK-TBI Investigators

The Lancet. Neurology

In Reply: Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury.

Burke JF, Yue JK, Ngwenya LB, Winkler EA, Talbott JF, Pan JZ, Ferguson AR, Beattie MS, Bresnahan JC, Haefeli J, Whetstone WD, Suen CG, Huang MC, Manley GT, Tarapore PE, Dhall SS

Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury.

Burke JF, Yue JK, Ngwenya LB, Winkler EA, Talbott JF, Pan JZ, Ferguson AR, Beattie MS, Bresnahan JC, Haefeli J, Whetstone WD, Suen CG, Huang MC, Manley GT, Tarapore PE, Dhall SS

Risk factors for hemorrhage of brain arteriovenous malformation.

Shaligram SS, Winkler E, Cooke D, Su H

CNS neuroscience & therapeutics

Commentary: Outcome After Clipping and Coiling for Aneurysmal Subarachnoid Hemorrhage in Clinical Practice in Europe, USA, and Australia.

Winkler EA, Rutledge WC, Abla AA

Transcortical transventricular transchoroidal-fissure approach to distal fusiform hyperplastic anterior choroidal artery aneurysms.

Rutledge C, Jonzzon S, Andrew Winkler E, Hetts SW, Abla AA

British journal of neurosurgery

Age and sex-mediated differences in six-month outcomes after mild traumatic brain injury in young adults: a TRACK-TBI study.

Yue JK, Levin HS, Suen CG, Morrissey MR, Runyon SJ, Winkler EA, Puffer RC, Deng H, Robinson CK, Rick JW, Phelps RRL, Sharma S, Taylor SR, Vassar MJ, Cnossen MC, Lingsma HF, Gardner RC, Temkin NR, Barber J, Dikmen SS, Yuh EL, Mukherjee P, Stein MB, Cage TA, Valadka AB, Okonkwo DO, Manley GT, TRACK-TBI Investigators

Neurological research

Comparative Analysis of the Subtonsillar, Far-Lateral, Extreme-Lateral, and Endoscopic Far-Medial Approaches to the Lower Clivus: An Anatomical Cadaver Study.

Wang M, Chae R, Vigo V, Winkler E, McDermott MW, El-Sayed IH, Abla AA, Rubio RR

World neurosurgery

Pre-injury Comorbidities Are Associated With Functional Impairment and Post-concussive Symptoms at 3- and 6-Months After Mild Traumatic Brain Injury: A TRACK-TBI Study.

Yue JK, Cnossen MC, Winkler EA, Deng H, Phelps RRL, Coss NA, Sharma S, Robinson CK, Suen CG, Vassar MJ, Schnyer DM, Puccio AM, Gardner RC, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Lingsma HF, Manley GT, TRACK-TBI Investigators

Frontiers in neurology

Clipping of High-Risk Dural Arteriovenous Fistula of the Posterior Fossa: 3-Dimensional Operative Video.

Rubio RR, Chae R, Rutledge WC, De Vilalta A, Kournoutas I, Winkler E, Abla AA

World neurosurgery

Local in situ fibrinolysis for recanalization of an occluded extracranial-intracranial bypass: Technical note.

Winkler EA, Raygor K, Caleb Rutledge W, Lu AP, Phelps RRL, Lien BV, Rubio RR, Abla AA

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Defective vascular signaling & prospective therapeutic targets in brain arteriovenous malformations.

Winkler EA, Lu AY, Raygor KP, Linzey JR, Jonzzon S, Lien BV, Rutledge WC, Abla AA

Neurochemistry international

Incidence, classification, and treatment of angiographically occult intracranial aneurysms found during microsurgical aneurysm clipping of known aneurysms.

Burkhardt JK, Chua MH, Winkler EA, Rutledge WC, Lawton MT

Journal of neurosurgery

National trends in cerebral bypass surgery in the United States, 2002-2014.

Winkler EA, Yue JK, Deng H, Raygor KP, Phelps RRL, Rutledge C, Lu AY, Rodriguez Rubio R, Burkhardt JK, Abla AA

Neurosurgical focus

Single-Barrel Versus Double-Barrel Superficial Temporal Artery to Middle Cerebral Artery Bypass: A Comparative Analysis.

Burkhardt JK, Winkler EA, Gandhi S, Lawton MT

World neurosurgery

Cerebrospinal fluid untargeted metabolomic profiling of aneurysmal subarachnoid hemorrhage: an exploratory study.

Lu AY, Damisah EC, Winkler EA, Grant RA, Eid T, Bulsara KR

British journal of neurosurgery

Nationwide Analysis of Cost Variation for Treatment of Aneurysmal Subarachnoid Hemorrhage.

Yoon S, Yoon JC, Winkler E, Liu C, Lawton MT

A2 Anterior Cerebral Artery-to-A3 Anterior Cerebral Artery Interpositional Bypass with Radial Artery Graft for a Ruptured Mycotic Fusiform Aneurysm: 2-Dimensional Operative Video.

Burkhardt JK, Winkler E, Tabani H, Gandhi S, Benet A, Lawton MT

Operative neurosurgery (Hagerstown, Md.)

A mini-open transspinous approach for resection of intramedullary spinal cavernous malformations.

Winkler EA, Lu A, Rutledge WC, Tabani H, Rodriguez Rubio R, Mummaneni PV, Abla AA

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Hospital complications and costs of spinal arteriovenous malformations in the United States from 2002-2014.

Yue JK, Deng H, Winkler EA, Ordaz A, Gillis-Buck EM, Lee YM, Safaee MM, Abla AA, Huang MC, Dhall SS

Journal of neurosurgical sciences

Temporal lobe contusions on computed tomography are associated with impaired 6-month functional recovery after mild traumatic brain injury: a TRACK-TBI study.

Yue JK, Winkler EA, Puffer RC, Deng H, Phelps RRL, Wagle S, Morrissey MR, Rivera EJ, Runyon SJ, Vassar MJ, Taylor SR, Cnossen MC, Lingsma HF, Yuh EL, Mukherjee P, Schnyer DM, Puccio AM, Valadka AB, Okonkwo DO, Manley GT

Neurological research

Adult Firearm-Related Traumatic Brain Injury in United States Trauma Centers.

Deng H, Yue JK, Winkler EA, Dhall SS, Manley GT, Tarapore PE

Journal of neurotrauma

Prediction of Persistent Post-Concussion Symptoms after Mild Traumatic Brain Injury.

Cnossen MC, van der Naalt J, Spikman JM, Nieboer D, Yue JK, Winkler EA, Manley GT, von Steinbuechel N, Polinder S, Steyerberg EW, Lingsma HF

Journal of neurotrauma

Predictors of 30-Day Outcomes in Octogenarians with Traumatic C2 Fractures Undergoing Surgery.

Yue JK, Ordaz A, Winkler EA, Deng H, Suen CG, Burke JF, Chan AK, Manley GT, Dhall SS, Tarapore PE

World neurosurgery

Concordance of common data elements for assessment of subjective cognitive complaints after mild-traumatic brain injury: a TRACK-TBI Pilot Study.

Ngwenya LB, Gardner RC, Yue JK, Burke JF, Ferguson AR, Huang MC, Winkler EA, Pirracchio R, Satris GG, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Manley GT

Timing, severity of deficits, and clinical improvement after surgery for spinal dural arteriovenous fistulas.

Safaee MM, Clark AJ, Burkhardt JK, Winkler EA, Lawton MT

Journal of neurosurgery. Spine

Thalidomide Reduces Hemorrhage of Brain Arteriovenous Malformations in a Mouse Model.

Zhu W, Chen W, Zou D, Wang L, Bao C, Zhan L, Saw D, Wang S, Winkler E, Li Z, Zhang M, Shen F, Shaligram S, Lawton M, Su H

Radiation-induced Cavernous Malformation as a Late Sequelae of Stereotactic Radiosurgery for Epilepsy.

Winkler EA, Rutledge C, Ward M, Tihan T, Sneed PK, Barbaro N, Garcia P, McDermott M, Chang EF

Identification of a rare BMP pathway mutation in a non-syndromic human brain arteriovenous malformation via exome sequencing.

Walcott BP, Winkler EA, Zhou S, Birk H, Guo D, Koch MJ, Stapleton CJ, Spiegelman D, Dionne-Laporte A, Dion PA, Kahle KT, Rouleau GA, Lawton MT

Human genome variation

Reductions in brain pericytes are associated with arteriovenous malformation vascular instability.

Winkler EA, Birk H, Burkhardt JK, Chen X, Yue JK, Guo D, Rutledge WC, Lasker GF, Partow C, Tihan T, Chang EF, Su H, Kim H, Walcott BP, Lawton MT

Journal of neurosurgery

Microsurgical resection of brain arteriovenous malformations in the elderly: outcomes analysis and risk stratification.

Burkhardt JK, Lasker GF, Winkler EA, Kim H, Lawton MT

Journal of neurosurgery

Reduction of shunt dependency rates following aneurysmal subarachnoid hemorrhage by tandem fenestration of the lamina terminalis and membrane of Liliequist during microsurgical aneurysm repair.

Winkler EA, Burkhardt JK, Rutledge WC, Rick JW, Partow CP, Yue JK, Birk H, Bach AM, Raygor KP, Lawton MT

Journal of neurosurgery

A longitudinal communication approach in advanced lung cancer: A qualitative study of patients', relatives' and staff's perspectives.

Villalobos M, Coulibaly K, Krug K, Kamradt M, Wensing M, Siegle A, Kuon J, Eschbach C, Tessmer G, Winkler E, Szecsenyi J, Ose D, Thomas M

European journal of cancer care

Efficacy of decompressive craniectomy in the management of intracranial pressure in severe traumatic brain injury.

Yue JK, Rick JW, Deng H, Feldman MJ, Winkler EA

Journal of neurosurgical sciences

Pericytes Regulate Cerebral Blood Flow and Neuronal Health at a Capillary Level.

Winkler EA, Rutledge WC, Kalani MYS, Rolston JD

Update on critical care for acute spinal cord injury in the setting of polytrauma.

Yue JK, Winkler EA, Rick JW, Deng H, Partow CP, Upadhyayula PS, Birk HS, Chan AK, Dhall SS

Neurosurgical focus

Early Hemodynamic Changes Based on Initial Color-Coding Angiography as a Predictor for Developing Subsequent Symptomatic Vasospasm After Aneurysmal Subarachnoid Hemorrhage.

Burkhardt JK, Chen X, Winkler EA, Weiss M, Yue JK, Cooke DL, Kim H, Lawton MT

World neurosurgery

Spine deformity surgery in the elderly: risk factors and 30-day outcomes are comparable in posterior versus combined approaches.

Yue JK, Sing DC, Sharma S, Upadhyayula PS, Winkler EA, Shaw JD, Metz LN

Neurological research

Comparing Plasma Phospho Tau, Total Tau, and Phospho Tau-Total Tau Ratio as Acute and Chronic Traumatic Brain Injury Biomarkers.

Rubenstein R, Chang B, Yue JK, Chiu A, Winkler EA, Puccio AM, Diaz-Arrastia R, Yuh EL, Mukherjee P, Valadka AB, Gordon WA, Okonkwo DO, Davies P, Agarwal S, Lin F, Sarkis G, Yadikar H, Yang Z, Manley GT, Wang KKW, the TRACK-TBI Investigators, Cooper SR, Dams-O'Connor K, Borrasso AJ, Inoue T, Maas AIR, Menon DK, Schnyer DM, Vassar MJ

Isolated abducens nerve palsy associated with subarachnoid hemorrhage: a localizing sign of ruptured posterior inferior cerebellar artery aneurysms.

Burkhardt JK, Winkler EA, Lasker GF, Yue JK, Lawton MT

Journal of neurosurgery

Laminoplasty versus laminectomy with posterior spinal fusion for multilevel cervical spondylotic myelopathy: influence of cervical alignment on outcomes.

Lau D, Winkler EA, Than KD, Chou D, Mummaneni PV

Journal of neurosurgery. Spine

Apolipoprotein E epsilon 4 (APOE-ε4) genotype is associated with decreased 6-month verbal memory performance after mild traumatic brain injury.

Yue JK, Robinson CK, Burke JF, Winkler EA, Deng H, Cnossen MC, Lingsma HF, Ferguson AR, McAllister TW, Rosand J, Burchard EG, Sorani MD, Sharma S, Nielson JL, Satris GG, Talbott JF, Tarapore PE, Korley FK, Wang KKW, Yuh EL, Mukherjee P, Diaz-Arrastia R, Valadka AB, Okonkwo DO, Manley GT, TRACK-TBI Investigators

Brain and behavior

Emergency department blood alcohol level associates with injury factors and six-month outcome after uncomplicated mild traumatic brain injury.

Yue JK, Ngwenya LB, Upadhyayula PS, Deng H, Winkler EA, Burke JF, Lee YM, Robinson CK, Ferguson AR, Lingsma HF, Cnossen MC, Pirracchio R, Korley FK, Vassar MJ, Yuh EL, Mukherjee P, Gordon WA, Valadka AB, Okonkwo DO, Manley GT, TRACK-TBI Investigators

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Mini-open spinal column shortening for the treatment of adult tethered cord syndrome.

Safaee MM, Winkler EA, Chou D

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Selective Serotonin Reuptake Inhibitors for Treating Neurocognitive and Neuropsychiatric Disorders Following Traumatic Brain Injury: An Evaluation of Current Evidence.

Yue JK, Burke JF, Upadhyayula PS, Winkler EA, Deng H, Robinson CK, Pirracchio R, Suen CG, Sharma S, Ferguson AR, Ngwenya LB, Stein MB, Manley GT, Tarapore PE

Contralateral posterior interhemispheric approach to deep medial parietooccipital vascular malformations: surgical technique and results.

Burkhardt JK, Winkler EA, Lawton MT

Journal of neurosurgery

The Traumatic Brain Injury Endpoints Development (TED) Initiative: Progress on a Public-Private Regulatory Collaboration To Accelerate Diagnosis and Treatment of Traumatic Brain Injury.

Manley GT, Mac Donald CL, Markowitz AJ, Stephenson D, Robbins A, Gardner RC, Winkler E, Bodien YG, Taylor SR, Yue JK, Kannan L, Kumar A, McCrea MA, Wang KK, TED Investigators

Journal of neurotrauma

Risk of Aneurysm Residual Regrowth, Recurrence, and de Novo Aneurysm Formation After Microsurgical Clip Occlusion Based on Follow-up with Catheter Angiography.

Burkhardt JK, Chua MHJ, Weiss M, Do ASS, Winkler EA, Lawton MT

World neurosurgery

Development of a Prediction Model for Post-Concussive Symptoms following Mild Traumatic Brain Injury: A TRACK-TBI Pilot Study.

Cnossen MC, Winkler EA, Yue JK, Okonkwo DO, Valadka AB, Steyerberg EW, Lingsma HF, Manley GT, TRACK-TBI Investigators

Journal of neurotrauma

Morbidity and Mortality Associated with Surgery of Traumatic C2 Fractures in Octogenarians.

Dhall SS, Yue JK, Winkler EA, Mummaneni PV, Manley GT, Tarapore PE

Delayed Venous Drainage in Ruptured Arteriovenous Malformations Based on Quantitative Color-Coded Digital Subtraction Angiography.

Burkhardt JK, Chen X, Winkler EA, Cooke DL, Kim H, Lawton MT

World neurosurgery

Bilateral External Ventricular Drain Placement and Intraventricular Irrigation Combined with Concomitant Serial Prone Patient Positioning: A Novel Treatment for Gravity-Dependent Layering in Bacterial Ventriculitis.

Chan AK, Birk HS, Yue JK, Winkler EA, McDermott MW

Vasopressor support in managing acute spinal cord injury: current knowledge.

Yue JK, Tsolinas RE, Burke JF, Deng H, Upadhyayula PS, Robinson CK, Lee YM, Chan AK, Winkler EA, Dhall SS

Journal of neurosurgical sciences

Erratum to: Surgical resection of fourth ventricular ependymomas: case series and technical nuances.

Winkler EA, Birk H, Safaee M, Yue JK, Burke JF, Viner JA, Pekmezci M, Perry A, Aghi MK, Berger MS, McDermott MW

Journal of neuro-oncology

Temporal profile of care following mild traumatic brain injury: predictors of hospital admission, follow-up referral and six-month outcome.

Yue JK, Winkler EA, Sharma S, Vassar MJ, Ratcliff JJ, Korley FK, Seabury SA, Ferguson AR, Lingsma HF, Deng H, Meeuws S, Adeoye OM, Rick JW, Robinson CK, Duarte SM, Yuh EL, Mukherjee P, Dikmen SS, McAllister TW, Diaz-Arrastia R, Valadka AB, Gordon WA, Okonkwo DO, Manley GT, the TRACK-TBI Investigators

DRD2 C957T polymorphism is associated with improved 6-month verbal learning following traumatic brain injury.

Yue JK, Winkler EA, Rick JW, Burke JF, McAllister TW, Oh SS, Burchard EG, Hu D, Rosand J, Temkin NR, Korley FK, Sorani MD, Ferguson AR, Lingsma HF, Sharma S, Robinson CK, Yuh EL, Tarapore PE, Wang KK, Puccio AM, Mukherjee P, Diaz-Arrastia R, Gordon WA, Valadka AB, Okonkwo DO, Manley GT, TRACK-TBI Investigators

Evaluating the effectiveness of organisational-level strategies with or without an activity tracker to reduce office workers' sitting time: a cluster-randomised trial.

Brakenridge CL, Fjeldsoe BS, Young DC, Winkler EA, Dunstan DW, Straker LM, Healy GN

The international journal of behavioral nutrition and physical activity

Surgical resection of fourth ventricular ependymomas: case series and technical nuances.

Winkler EA, Birk H, Safaee M, Yue JK, Burke JF, Viner JA, Pekmezci M, Perry A, Aghi MK, Berger MS, McDermott MW

Journal of neuro-oncology

COMT Val158Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury.

Winkler EA, Yue JK, Ferguson AR, Temkin NR, Stein MB, Barber J, Yuh EL, Sharma S, Satris GG, McAllister TW, Rosand J, Sorani MD, Lingsma HF, Tarapore PE, Burchard EG, Hu D, Eng C, Wang KK, Mukherjee P, Okonkwo DO, Diaz-Arrastia R, Manley GT, TRACK-TBI Investigators

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Circadian variability of the initial Glasgow Coma Scale score in traumatic brain injury patients.

Yue JK, Robinson CK, Winkler EA, Upadhyayula PS, Burke JF, Pirracchio R, Suen CG, Deng H, Ngwenya LB, Dhall SS, Manley GT, Tarapore PE

Neurobiology of sleep and circadian rhythms

Cerebral Edema in Traumatic Brain Injury: Pathophysiology and Prospective Therapeutic Targets.

Winkler EA, Minter D, Yue JK, Manley GT

Neurosurgery clinics of North America

Feasibility, effectiveness and cost-effectiveness of a telephone-based weight loss program delivered via a hospital outpatient setting.

Whelan ME, Goode AD, Eakin EG, Veerman JL, Winkler EA, Hickman IJ, Reeves MM

Translational behavioral medicine

Molecular, Cellular, and Genetic Determinants of Sporadic Brain Arteriovenous Malformations.

Walcott BP, Winkler EA, Rouleau GA, Lawton MT

Stability of Programmable Shunt Valve Settings with Simultaneous Use of the Optune Transducer Array: A Case Report.

Chan AK, Birk HS, Winkler EA, Viner JA, Taylor JW, McDermott MW

Screening for Post-Traumatic Stress Disorder in a Civilian Emergency Department Population with Traumatic Brain Injury.

Haarbauer-Krupa J, Taylor CA, Yue JK, Winkler EA, Pirracchio R, Cooper SR, Burke JF, Stein MB, Manley GT

Journal of neurotrauma

Odontoid fractures in the octogenarian: a systematic review and meta-analysis.

Deng H, Yue JK, Upadhyayula PS, Burke JF, Suen CG, Chan AK, Winkler EA, Dhall SS

Journal of neurosurgical sciences

Obesity Is an Independent Risk Factor of Early Complications After Revision Spine Surgery.

Sing DC, Yue JK, Metz LN, Winkler EA, Zhang WR, Burch S, Berven SH

Clinical utility and cost analysis of routine postoperative head CT in elective aneurysm clippings.

Zygourakis CC, Winkler E, Pitts L, Hannegan L, Franc B, Lawton MT

Journal of neurosurgery

Adult sports-related traumatic brain injury in United States trauma centers.

Winkler EA, Yue JK, Burke JF, Chan AK, Dhall SS, Berger MS, Manley GT, Tarapore PE

Neurosurgical focus

Pediatric sports-related traumatic brain injury in United States trauma centers.

Yue JK, Winkler EA, Burke JF, Chan AK, Dhall SS, Berger MS, Manley GT, Tarapore PE

Neurosurgical focus

Rate of perioperative neurological complications after surgery for cervical spinal cord stimulation.

Chan AK, Winkler EA, Jacques L

Journal of neurosurgery. Spine

Plasma Anti-Glial Fibrillary Acidic Protein Autoantibody Levels during the Acute and Chronic Phases of Traumatic Brain Injury: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Pilot Study.

Wang KK, Yang Z, Yue JK, Zhang Z, Winkler EA, Puccio AM, Diaz-Arrastia R, Lingsma HF, Yuh EL, Mukherjee P, Valadka AB, Gordon WA, Okonkwo DO, Manley GT, Cooper SR, Dams-O'Connor K, Hricik AJ, Inoue T, Maas AI, Menon DK, Schnyer DM, Sinha TK, Vassar MJ

Journal of neurotrauma

Accelerated pericyte degeneration and blood-brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer's disease.

Halliday MR, Rege SV, Ma Q, Zhao Z, Miller CA, Winkler EA, Zlokovic BV

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

A review and update on the current and emerging clinical trials for the acute management of cervical spine and spinal cord injuries - Part III.

Yue JK, Upadhyayula PS, Chan AK, Winkler EA, Burke JF, Readdy WJ, Sharma S, Deng H, Dhall SS

Journal of neurosurgical sciences

COMT Val 158 Met polymorphism is associated with nonverbal cognition following mild traumatic brain injury.

Winkler EA, Yue JK, McAllister TW, Temkin NR, Oh SS, Burchard EG, Hu D, Ferguson AR, Lingsma HF, Burke JF, Sorani MD, Rosand J, Yuh EL, Barber J, Tarapore PE, Gardner RC, Sharma S, Satris GG, Eng C, Puccio AM, Wang KK, Mukherjee P, Valadka AB, Okonkwo DO, Diaz-Arrastia R, Manley GT, TRACK-TBI Investigators

Perioperative morbidity and mortality after lumbar trauma in the elderly.

Winkler EA, Yue JK, Birk H, Robinson CK, Manley GT, Dhall SS, Tarapore PE

Neurosurgical focus

A Tunneled Subcricoid Approach for Anterior Cervical Spine Reoperation: Technical and Safety Results.

Winkler EA, Rowland NC, Yue JK, Birk H, Ozpinar A, Tay B, Ames CP, Mummaneni PV, El-Sayed IH

World neurosurgery

A review and update on the guidelines for the acute management of cervical spinal cord injury - Part II.

Yue JK, Chan AK, Winkler EA, Upadhyayula PS, Readdy WJ, Dhall SS

Journal of neurosurgical sciences

The Presto 1000: A novel automated transcranial Doppler ultrasound system.

Han SJ, Rutledge WC, Englot DJ, Winkler EA, Browne JL, Pflugrath L, Cronsier D, Abla AA, Kliot M, Lawton MT

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.

Zhao Z, Sagare AP, Ma Q, Halliday MR, Kong P, Kisler K, Winkler EA, Ramanathan A, Kanekiyo T, Bu G, Owens NC, Rege SV, Si G, Ahuja A, Zhu D, Miller CA, Schneider JA, Maeda M, Maeda T, Sugawara T, Ichida JK, Zlokovic BV

Nature neuroscience

GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration.

Winkler EA, Nishida Y, Sagare AP, Rege SV, Bell RD, Perlmutter D, Sengillo JD, Hillman S, Kong P, Nelson AR, Sullivan JS, Zhao Z, Meiselman HJ, Wendy RB, Soto J, Abel ED, Makshanoff J, Zuniga E, De Vivo DC, Zlokovic BV

Nature neuroscience

Association of a common genetic variant within ANKK1 with six-month cognitive performance after traumatic brain injury.

Yue JK, Pronger AM, Ferguson AR, Temkin NR, Sharma S, Rosand J, Sorani MD, McAllister TW, Barber J, Winkler EA, Burchard EG, Hu D, Lingsma HF, Cooper SR, Puccio AM, Okonkwo DO, Diaz-Arrastia R, Manley GT, COBRIT Investigators, TRACK-TBI Investigators

The pericyte: a forgotten cell type with important implications for Alzheimer's disease?

Winkler EA, Sagare AP, Zlokovic BV

Brain pathology (Zurich, Switzerland)

Blood-spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice.

Winkler EA, Sengillo JD, Sagare AP, Zhao Z, Ma Q, Zuniga E, Wang Y, Zhong Z, Sullivan JS, Griffin JH, Cleveland DW, Zlokovic BV

Proceedings of the National Academy of Sciences of the United States of America

Six-month outcomes from living well with diabetes: A randomized trial of a telephone-delivered weight loss and physical activity intervention to improve glycemic control.

Eakin EG, Reeves MM, Winkler E, Healy GN, Dunstan DW, Owen N, Marshal AM, Wilkie KC

Annals of behavioral medicine : a publication of the Society of Behavioral Medicine

Chronic γ-secretase inhibition reduces amyloid plaque-associated instability of pre- and postsynaptic structures.

Liebscher S, Page RM, Käfer K, Winkler E, Quinn K, Goldbach E, Brigham EF, Quincy D, Basi GS, Schenk DB, Steiner H, Bonhoeffer T, Haass C, Meyer-Luehmann M, Hübener M

Molecular psychiatry

Pericyte loss influences Alzheimer-like neurodegeneration in mice.

Sagare AP, Bell RD, Zhao Z, Ma Q, Winkler EA, Ramanathan A, Zlokovic BV

Nature communications

Deficiency in mural vascular cells coincides with blood-brain barrier disruption in Alzheimer's disease.

Sengillo JD, Winkler EA, Walker CT, Sullivan JS, Johnson M, Zlokovic BV

Brain pathology (Zurich, Switzerland)

Blood-spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis.

Winkler EA, Sengillo JD, Sullivan JS, Henkel JS, Appel SH, Zlokovic BV

Acta neuropathologica

Blood-spinal cord barrier pericyte reductions contribute to increased capillary permeability.

Winkler EA, Sengillo JD, Bell RD, Wang J, Zlokovic BV

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Apolipoprotein E controls cerebrovascular integrity via cyclophilin A.

Bell RD, Winkler EA, Singh I, Sagare AP, Deane R, Wu Z, Holtzman DM, Betsholtz C, Armulik A, Sallstrom J, Berk BC, Zlokovic BV

Central nervous system pericytes in health and disease.

Winkler EA, Bell RD, Zlokovic BV

Nature neuroscience

Stuck at the bench: Potential natural neuroprotective compounds for concussion.

Petraglia AL, Winkler EA, Bailes JE

Surgical neurology international

From the liver to the blood-brain barrier: an interconnected system regulating brain amyloid-β levels.

Sagare AP, Winkler EA, Bell RD, Deane R, Zlokovic BV

Journal of neuroscience research

Microhemorrhages: undetectable but clinically meaningful the question persists.

Zhong Z, Winkler EA, Zlokovic BV

Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases

Lack of Smad or Notch leads to a fatal game of brain pericyte hopscotch.

Winkler EA, Bell RD, Zlokovic BV

Developmental cell

Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging.

Bell RD, Winkler EA, Sagare AP, Singh I, LaRue B, Deane R, Zlokovic BV

Low-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer's amyloid β-peptide elimination from the brain.

Zlokovic BV, Deane R, Sagare AP, Bell RD, Winkler EA

Journal of neurochemistry

Pericyte-specific expression of PDGF beta receptor in mouse models with normal and deficient PDGF beta receptor signaling.

Winkler EA, Bell RD, Zlokovic BV

Molecular neurodegeneration

Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor.

Zhu D, Wang Y, Singh I, Bell RD, Deane R, Zhong Z, Sagare A, Winkler EA, Zlokovic BV

The intraflagellar transport protein ift80 is essential for photoreceptor survival in a zebrafish model of jeune asphyxiating thoracic dystrophy.

Hudak LM, Lunt S, Chang CH, Winkler E, Flammer H, Lindsey M, Perkins BD

Investigative ophthalmology & visual science

Endoproteolysis of the ER stress transducer ATF6 in the presence of functionally inactive presenilins.

Steiner H, Winkler E, Shearman MS, Prywes R, Haass C

Neurobiology of disease

Two p16 (CDKN2A) germline mutations in 30 Israeli melanoma families.

Yakobson E, Shemesh P, Azizi E, Winkler E, Lassam N, Hogg D, Brookes S, Peters G, Lotem M, Zlotogorski A, Landau M, Safro M, Shafir R, Friedman E, Peretz H

European journal of human genetics : EJHG

Use of flumazenil in the diagnosis and treatment of patients with coma of unknown etiology.

Winkler E, Almog S, Kriger D, Tirosh MS, Halkin H, Ezra D

Critical Care Medicine

Role of cholecystostomy in the management of critically ill patients suffering from acute cholecystitis.

Winkler E, Kaplan O, Gutman M, Skornick Y, Rozin RR

The British journal of surgery

[Biochemical examination of bronchial secretion in children with aspecific chronic bronchopneumopathies].

Dietzsch HJ, Gottschalk B, Klemm E, Mittenzwey KW, Winkler E

The influence of tetracyclines for intravenous application on the pulmonary and circulatory functions of healthy persons and patients with chronic bronchitis.

Krekeler H, von Nieding G, Schoog M, Smidt U, Weih H, Winkler E

Arzneimittel-Forschung