Education 09/2021 - Diversity, Equity, and Inclusion Champion Training, University of California, San FranciscoM.A.S. in Clinical Research, 2012 - Graduate Division (Advance Training in Clinical Research), University of California, San FranciscoM.D., 2004 - Medicine, University of California, San Francisco Publications Improving understanding of long-term cognitive recovery after childhood ischemic stroke. Fox CK 4D flow MRI for noninvasive monitoring of high-flow vascular malformations in neonates and infants: A feasibility study. Massachi JA, Yoo C, Walia S, Schollenberger J, Saloner D, Kim H, Fox CK, Fullerton HJ, Hetts SW, Narsinh KH Thrombectomy Versus Medical Management for Pediatric Arterial Ischemic Stroke With Large Baseline Infarct. Bhatia KD, Muthusami P, Parra-Farinas C, Pulcine E, Chowdhury S, Dlamini N, Andrews I, Gupta S, Webster R, Troedson C, Dale RC, Miteff F, Miteff C, Fox CK, Dmytriw AA, Lee S, Fiehler J, Abruzzo T, Pabst L, Fraser S, Sun LR, Boulouis G, Nguyen-Kim TDL, Wildgruber M, Sporns PB Assessing the Impact of the COVID-19 Pandemic on Childhood Arterial Ischemic Stroke: An Unanticipated Natural Experiment. Fullerton HJ, Hills NK, Wintermark M, Dlamini N, Fox CK, Cummings DD, Bernard TJ, Beslow LA, Sun LR, Grose C, Norris PJ, Di Germanio C, VIPS II Investigators Focal Cerebral Injury in Pediatric Extracorporeal Life Support: Timing in Relation to Cannulation or Other Circuit Events in a Single-Center Retrospective Series, 2015-2023. Caffarelli M, Li Y, Amorim E, Finlay K, Guterman EL, Benedetti G, Press CA, Harrar D, Thomas AX, Steurer M, Sacks LD, Fox CK A Quantitative Electroencephalographic Index for Stroke Detection in Adults. Caffarelli M, Simmons R, Tolokh I, Karukonda V, Guterman EL, Smith W, Fox CK, Westover MB, Amorim E Abstract TMP88: Clinical Utility of Genetic Testing in Pediatric and Young Adult Hemorrhagic Stroke and Cerebrovascular Malformations. Rachel Vassar, Joseph Shieh, Ethan Winkler, Shantel Weinsheimer, Daniel Cooke, Steven Hetts, Nerissa Ko, Christine Fox, Heather Fullerton, Helen Kim Abstract TMP94: Mental Health Outcomes In Parents with Children with Pediatric Arterial Ischemic Stroke. Laura Lehman, Lauren Beslow, Nomazulu Dlamini, Adam Kirton, Kristin Guilliams, John Taylor, Daniel Fain, Hannah Glass, Lindsay Peglar, Mubeen Rafay, Michael Dowling, Paola Pergami, Christine Fox Endovascular thrombectomy for childhood stroke (Save ChildS Pro): an international, multicentre, prospective registry study. Sporns PB, Bhatia K, Abruzzo T, Pabst L, Fraser S, Chung MG, Lo W, Othman A, Steinmetz S, Jensen-Kondering U, Schob S, Kaiser DPO, Marik W, Wendl C, Kleffner I, Henkes H, Kraehling H, Nguyen-Kim TDL, Chapot R, Yilmaz U, Wang F, Hafeez MU, Requejo F, Limbucci N, Kauffmann B, Möhlenbruch M, Nikoubashman O, Schellinger PD, Musolino P, Alawieh A, Wilson J, Grieb D, Gersing AS, Liebig T, Olivieri M, Schwabova JP, Tomek A, Papanagiotou P, Boulouis G, Naggara O, Fox CK, Orlov K, Kuznetsova A, Parra-Farinas C, Muthusami P, Regenhardt RW, Dmytriw AA, Burkard T, Martinez M, Brechbühl D, Steinlin M, Sun LR, Hassan AE, Kemmling A, Lee S, Fullerton HJ, Fiehler J, Psychogios MN, Wildgruber M Congenital Heart Disease, Atrial Fibrillation, and Ischemic Stroke Risk. Fox CK, Kamel H Stroke Mimics in Children With Moyamoya Arteriopathy. Ariana J. Andere, Jasmin Dao, Amy A. Gelfand, Ramin A. Morshed, Alexandra C. Ross, Amanda E. Wagstaff, Heather J. Fullerton, Christine K. Fox Silent Cerebral Infarcts in Adults With Sickle Cell Disease: Expanding Beyond Childhood Borders. Dain AS, Fox CK Pediatric Arterial Ischemic Stroke. Catherine Amlie-Lefond, Christine K. Fox Risk factors associated with in-hospital complications for pediatric sickle-cell disease-associated moyamoya syndrome: a nationwide cross-sectional study. Osorio RC, Raygor KP, Rinaldo L, Fox CK, Bhasin N, Abla AA, Gupta N Abstract 112: Assessing the Impact of the COVID-19 Pandemic on Childhood Arterial Ischemic Stroke: An Unanticipated Natural Experiment. Heather J Fullerton, Clara Di Germanio, Nancy K Hills, Lauren A Beslow, Dana D Cummings, Nomazulu Dlamini, Christine K Fox, Lisa R Sun, Philip Norris Abstract TMP2: Longitudinal Risk of Seizures in Patients With Brain Arteriovenous Malformations. Samyami S Chowdhury, Jeffrey Nelson, Shantel Weinsheimer, Jonas Schollenberger, Heather J Fullerton, Christine K Fox, Helen Kim Abstract TMP60: Contralesional Brain Regions Mirror the Volume Changes of Their Homologous Counterparts in the Ipsilesional Hemisphere in Children During the First Year After Unilateral Intracerebral Hemorrhage. Hannah L Choi, Shivani Mahuvakar, Lanya T Cai, Helen Kim, David A Saloner, Christine K Fox, Jarod Roland, Heather J Fullerton, Pratik Mukherjee Abstract TP6: Identification of Circulating Epigenetic Biomarkers for Seizure in Brain Arteriovenous Malformation by Methylome Profiling. Peter Park, Jeffrey Nelson, Christine K Fox, Adam Numis, Nerissa Ko, Ethan Winkler, Charles McCulloch, Helen Kim, Shantel Weinsheimer Abstract WP217: 4D Flow MRI Monitoring of Pediatric Brain Arteriovenous Malformations: A Feasibility Study. Jonas Schollenberger, Shivani Mahuvakar, Christine K Fox, Pratik Mukherjee, Heather J Fullerton, Helen Kim, David Saloner Multicenter Study of Long-Term Outcomes and Quality of Life in PHACE Syndrome after Age 10. Braun M, Frieden IJ, Siegel DH, George E, Hess CP, Fox CK, Chamlin SL, Drolet BA, Metry D, Pope E, Powell J, Holland K, Ulschmid C, Liang MG, Barry KK, Ho T, Cotter C, Baselga E, Bosquez D, Jain SN, Bui JK, Lara-Corrales I, Funk T, Small A, Baghoomian W, Yan AC, Treat JR, Hogrogian GS, Huang C, Haggstrom A, List M, McCuaig CC, Barrio V, Mancini AJ, Lawley LP, Grunnet-Satcher K, Horii KA, Newell B, Nopper A, Garzon MC, Scollan ME, Mathes EF A quantitative EEG index for the recognition of arterial ischemic stroke in children. Caffarelli M, Karukonda V, Aghaeeaval M, McQuillen PS, Numis AL, Mackay MT, Press CA, Wintermark M, Fox CK, Amorim E, SIPS Investigators 350 A Comparison of Incidental and Symptomatic Unruptured Brain Arteriovenous Malformations in Children. Alex Y. Lu, Ethan A. Winkler, Joseph Garcia, Kunal P. Raygor, Heather Fullerton, Christine Fox, Helen Kim, Kurtis Ian Auguste, Peter P. Sun, Steven Hetts, Michael T. Lawton, Adib Adnan Abla, Nalin Gupta A comparison of incidental and symptomatic unruptured brain arteriovenous malformations in children. Lu AY, Winkler EA, Garcia JH, Raygor KP, Fullerton HJ, Fox CK, Kim H, Auguste KI, Sun PP, Hetts SW, Lawton MT, Abla AA, Gupta N Abstract 52: Prevalence Of Somatic Activating Kras Mutations In Pediatric And Adult Sporadic Brain Arteriovenous Malformations. Ethan A Winkler, Joseph Garcia, Cynthia Tsang, Jeffrey Nelson, Charles McCulloch, Shantel Weinsheimer, Christine K Fox, Heather Fullerton, Nerissa Ko, Hua Su, Tomasz Nowakowski, Daniel L Cooke, Steven Hetts, Ekin Guney, MELIKE PEKMEZCI, Tarik Tihan, Michael Lawton, Adib Abla, Nalin Gupta, Helen Kim Abstract TP157: Interleukin Plasma Levels And Risk Of Hemorrhage In Pediatric Brain Arteriovenous Malformation Patients. Shweta A Chawla, Shantel Weinsheimer, Jeffrey Nelson, Charles McCulloch, Adib Abla, Nalin Gupta, Daniel L Cooke, Steven Hetts, David Saloner, Yi Li, Christine K Fox, Heather J Fullerton, Helen Kim Hemorrhagic Stroke in Children and Adults With Sickle Cell Anemia: The Post-STOP Cohort. Fox CK, Leykina L, Hills NK, Kwiatkowski JL, Kanter J, Strouse JJ, Voeks JH, Fullerton HJ, Adams RJ, Post-STOP Study Group Socioeconomic factors associated with pediatric moyamoya disease hospitalizations: a nationwide cross-sectional study. Raygor KP, Phelps RRL, Rutledge C, Raper DMS, Molinaro A, Fox CK, Gupta N, Abla AA Validation of the Ruptured Arteriovenous Malformation Grading Scale in a pediatric cohort. Garcia JH, Rutledge C, Winkler EA, Carrete L, Morshed RA, Lu AY, Saggi S, Fox CK, Fullerton HJ, Kim H, Cooke DL, Hetts SW, Lawton MT, Gupta N, Abla AA Maximizing Brain Health After Hemorrhagic Stroke: Bugher Foundation Centers of Excellence. Sheth KN, Anderson CD, Biffi A, Dlamini N, Falcone GJ, Fox CK, Fullerton HJ, Greenberg SM, Hemphill JC, Kim A, Kim H, Ko NU, Roland JL, Sansing LH, van Veluw SJ, Rosand J Abstract TMP91: Healthcare Utilization For Headache And Anxiety After Surgical Revascularization In Children With Moyamoya Vasculopathy. Ariana J Andere, Jasmin Dao, Amy Gelfand, Heather J Fullerton, Christine K Fox Factors associated with seizures at initial presentation in pediatric patients with cerebral arteriovenous malformations. Garcia JH, Winkler EA, Morshed RA, Lu A, Ammanuel SG, Saggi S, Wang EJ, Braunstein S, Fox CK, Fullerton HJ, Kim H, Cooke DL, Hetts SW, Lawton MT, Abla AA, Gupta N Modified Pediatric ASPECTS: Building Tools for Future Pediatric Stroke Studies. Lee S, Fox CK Seizure Incidence Rates in Children and Adults With Familial Cerebral Cavernous Malformations. Fox CK, Nelson J, McCulloch CE, Weinsheimer S, Pawlikowska L, Hart B, Mabray MC, Zafar A, Morrison L, Zabramski JM, Akers A, Kim H Assessing the association of common genetic variants in EPHB4 and RASA1 with phenotype severity in familial cerebral cavernous malformation. Choksi F, Weinsheimer S, Nelson J, Pawlikowska L, Fox CK, Zafar A, Mabray MC, Zabramski J, Akers A, Hart BL, Morrison L, McCulloch CE, Kim H Long-Term Risk of Epilepsy After Pediatric Stroke and Potential Genetic Vulnerabilities. Beslow LA, Helbig I, Fox CK Pediatric moyamoya MRI score: an imaging-based scale to predict outcomes in surgically treated pediatric patients with moyamoya. Garcia JH, Morshed RA, Winkler EA, Li Y, Fox CK, Fullerton HJ, Rutledge C, Beniwal AS, Lawton MT, Abla AA, Gupta N, Hetts SW Multiple Tumor-Associated Intracranial Aneurysms Adjacent to a Suprasellar Germ Cell Tumor: Case Report and Review of Literature. Yue JK, Chang D, Oh T, Winkler EA, Lu AY, Hetts SW, Young EP, Reddy AT, Fox CK, Abla AA, Roland JL Pediatric Ischemic Stroke: An Infrequent Complication of SARS-CoV-2. Beslow LA, Linds AB, Fox CK, Kossorotoff M, Zuñiga Zambrano YC, Hernández-Chávez M, Hassanein SMA, Byrne S, Lim M, Maduaka N, Zafeiriou D, Dowling MM, Felling RJ, Rafay MF, Lehman LL, Noetzel MJ, Bernard TJ, Dlamini N, International Pediatric Stroke Study Group Asymptomatic rotational vertebral artery compression in a child due to head positioning for cranial surgery: illustrative case. Caton MT, Narsinh K, Baker A, Abla AA, Roland JL, Halbach VV, Fox CK, Fullerton HJ, Hetts SW Clinical outcomes after revascularization for pediatric moyamoya disease and syndrome: A single-center series. Morshed RA, Abla AA, Murph D, Dao JM, Winkler EA, Burkhardt JK, Colao K, Hetts SW, Fullerton HJ, Lawton MT, Gupta N, Fox CK Single-center series of boys with recurrent strokes and rotational vertebral arteriopathy. Fox CK, Fullerton HJ, Hetts SW, Halbach VV, Auguste KI, Lawton MT, Gupta N Bringing high-grade arteriovenous malformations under control: clinical outcomes following multimodality treatment in children. Winkler EA, Lu A, Morshed RA, Yue JK, Rutledge WC, Burkhardt JK, Patel AB, Ammanuel SG, Braunstein S, Fox CK, Fullerton HJ, Kim H, Cooke D, Hetts SW, Lawton MT, Abla AA, Gupta N Validation of the pediatric stroke outcome measure for classifying overall neurological deficit. Slim M, Fox CK, Friefeld S, Dlamini N, Westmacott R, Moharir M, MacGregor D, deVeber G, SIPS Investigators Review on the Diagnosis and Treatment of Reversible Cerebral Vasoconstriction Syndrome in Children and Adolescents. Qubty W, Irwin SL, Fox CK Abstract 89: Incidence and Characteristics of Hemorrhagic Stroke Among Post-STOP Participants. Liza A Leykina, Christine K Fox, Nancy K Hills, Julie Kanter, Janet L Kwiatkowski, Ariana Tinker, Jenifer H Voeks, Heather J Fullerton, Robert J Adams Endovascular Therapy for Childhood Stroke-Working Together to Reach Prime Time. Fox C, Dlamini N Comparative study of posterior and anterior circulation stroke in childhood: Results from the International Pediatric Stroke Study. Goeggel Simonetti B, Rafay MF, Chung M, Lo WD, Beslow LA, Billinghurst LL, Fox CK, Pagnamenta A, Steinlin M, Mackay MT, IPSS Study Group Seizures and outcome one year after neonatal and childhood cerebral sinovenous thrombosis. Aleksandra Mineyko, Adam Kirton, Lori Billinghurst, Nana Nino Tatishvili, Max Wintermark, Gabrielle deVeber, Christine Fox, SIPS Investigators Clinical and Imaging Outcomes After Combined Direct and Indirect Bypass for Pediatric Moyamoya Disease: A Single Center Retrospective Series. Ramin A Morshed, Daniel Murph, Jasmin Dao, Kathleen Colao, Lauro Avalos, Steven Hetts, Adib A Abla, Christine Fox, Michael T Lawton, Nalin Gupta Arterial Ischemic Stroke Secondary to Cardiac Disease in Neonates and Children. Chung MG, Guilliams KP, Wilson JL, Beslow LA, Dowling MM, Friedman NR, Hassanein SMA, Ichord R, Jordan LC, Mackay MT, Rafay MF, Rivkin M, Torres M, Zafeiriou D, deVeber G, Fox CK, International Pediatric Stroke Study Investigators Arteriopathy Influences Pediatric Ischemic Stroke Presentation, but Sickle Cell Disease Influences Stroke Management. Guilliams KP, Kirkham FJ, Holzhauer S, Pavlakis S, Philbrook B, Amlie-Lefond C, Noetzel MJ, Dlamini N, Sharma M, Carpenter JL, Fox CK, Torres M, Ichord RN, Jordan LC, Dowling MM Abstract TMP51: Pre-existing Atherosclerotic Risk Factors Increase Short-Term Ischemic Stroke Risk After Traumatic Head or Neck Injury. Helayne R Feferman, Heather J Fullerton, Adam Numis, Nancy K Hills, David R Vinson, Stephen Sidney, Christine K Fox Socioeconomic determinants of outcome after childhood arterial ischemic stroke. Jordan LC, Hills NK, Fox CK, Ichord RN, Pergami P, deVeber GA, Fullerton HJ, Lo W, VIPS Investigators Children with post-stroke epilepsy have poorer outcomes one year after stroke. Fox CK, Jordan LC, Beslow LA, Armstrong J, Mackay MT, deVeber G Abstract 18: Anticonvulsant Medication Practice Varies After Pediatric Arterial Ischemic Stroke. Kristin P Guiliams, Michael M Dowling, Dimitrios I Zafeiriou, Neil Friedman, Gabrielle deVeber, Christine K Fox 803. Helayne Feferman, Christine Fox, Heather Fullerton Population-based study of ischemic stroke risk after trauma in children and young adults. Fox CK, Hills NK, Vinson DR, Numis AL, Dicker RA, Sidney S, Fullerton HJ Abstract WMP111: Socioeconomic Determinants of Outcome After Childhood Arterial Ischemic Stroke. Lori C Jordan, Nancy K Hills, Warren Lo, Rebecca N Ichord, Christine K Fox, Paola Pergami, Jorina Elbers, Gabrielle A deVeber, Heather J Fullerton Inflammatory Biomarkers in Childhood Arterial Ischemic Stroke: Correlates of Stroke Cause and Recurrence. Fullerton HJ, deVeber GA, Hills NK, Dowling MM, Fox CK, Mackay MT, Kirton A, Yager JY, Bernard TJ, Hod EA, Wintermark M, Elkind MS, VIPS Investigators Prolonged or recurrent acute seizures after pediatric arterial ischemic stroke are associated with increasing epilepsy risk. Fox CK, Mackay MT, Dowling MM, Pergami P, Titomanlio L, Deveber G, SIPS Investigators Indirect and direct revascularization of ACTA2 cerebral arteriopathy: feasibility of the superficial temporal artery to anterior cerebral artery bypass with posterior auricular artery interposition graft: case report. Rutledge WC, Choudhri O, Walcott BP, Benet A, Fox CK, Gupta N, Lawton MT Neonatal seizures triple the risk of a remote seizure after perinatal ischemic stroke. Fox CK, Glass HC, Sidney S, Smith SE, Fullerton HJ Abstract WMP103: Epilepsy is Associated With Poorer Neurologic Outcome After Pediatric Arterial Ischemic Stroke. Christine K Fox, Lori C Jordan, Mark T Mackay, Gabrielle deVeber Abstract WP201: Ischemic Stroke Risk After Traumatic Head or Neck Injury. Christine K Fox, Nancy K Hills, Stephen Sidney, David R Vinson, Heather J Fullerton Community-based case-control study of childhood stroke risk associated with congenital heart disease. Fox CK, Sidney S, Fullerton HJ Stroke in children with cardiac disease: report from the International Pediatric Stroke Study Group Symposium. Sinclair AJ, Fox CK, Ichord RN, Almond CS, Bernard TJ, Beslow LA, Chan AK, Cheung M, deVeber G, Dowling MM, Friedman N, Giglia TM, Guilliams KP, Humpl T, Licht DJ, Mackay MT, Jordan LC Abstract T MP66: Injury to the Head or Neck Increases Risk of Ischemic Stroke Three-fold After Trauma. Christine K Fox, Adam L Numis, Steve Sidney, Heather J Fullerton Arterial ischemic stroke in children: risk factors and etiologies. Numis AL, Fox CK Acute seizures predict epilepsy after childhood stroke. Fox CK, Glass HC, Sidney S, Lowenstein DH, Fullerton HJ Abstract 77: Posterior Circulation Stroke in Children Due to Cervical Spine Abnormalities. Christine K Fox, Charles E Stout, Nalin Gupta, Michael T Lawton, Christopher F Dowd, Heather J Fullerton High critical care usage due to pediatric stroke: results of a population-based study. Fox CK, Johnston SC, Sidney S, Fullerton HJ Abstract 41: Acute Seizures and Neurologic Deficits Predict Epilepsy After Pediatric Stroke. Christine K Fox, Hannah C Glass, S. Claiborne Johnston, Stephen Sidney, Mai N Nguyen-Huynh, Heather J Fullerton Recent advances in childhood arterial ischemic stroke. Fox CK, Fullerton HJ Minocycline Confers Early but Transient Protection in the Immature Brain following Focal Cerebral Ischemiareperfusion. Christine Fox, Andra Dingman, Nikita Derugin, Michael F Wendland, Catherine Manabat, Shaoquan Ji, Donna M Ferriero, Zinaida S Vexler Magnetic resonance imaging as a surrogate measure for histological sub-chronic endpoint in a neonatal rat stroke model. Derugin N, Dingman A, Wendland MF, Fox C, Bollen A, Vexler ZS Minocycline confers early but transient protection in the immature brain following focal cerebral ischemia-reperfusion. Fox C, Dingman A, Derugin N, Wendland MF, Manabat C, Ji S, Ferriero DM, Vexler ZS Infant botulism, type F, presenting at 54 hours of life. Keet CA, Fox CK, Margeta M, Marco E, Shane AL, Dearmond SJ, Strober JB, Miller SP Recent advances in infant botulism. Fox CK, Keet CA, Strober JB Regulation of hypoxia-inducible factor 1alpha and induction of vascular endothelial growth factor in a rat neonatal stroke model. Mu D, Jiang X, Sheldon RA, Fox CK, Hamrick SE, Vexler ZS, Ferriero DM Reperfusion differentially induces caspase-3 activation in ischemic core and penumbra after stroke in immature brain. Manabat C, Han BH, Wendland M, Derugin N, Fox CK, Choi J, Holtzman DM, Ferriero DM, Vexler ZS Apoptotic pathways in primary biliary cirrhosis and autoimmune hepatitis. Fox CK, Furtwaengler A, Nepomuceno RR, Martinez OM, Krams SM DIFFERENTIAL EFFECTS OF CD4 AND CD8 CELLS ON APOPTOSIS IN SMALL INTESTINAL TRANSPLANTATION. Sheri M. Krams, Karen J. Whitmer, Michihiro Hayashi, Christine Fox, Carlos O. Esquivel, Olivia M. Martinez DIFFERENTIAL EFFECTS OF CD4 AND CD8 CELLS ON APOPTOSIS IN SMALL INTESTINAL TRANSPLANTATION. Sheri M. Krams, Karen J. Whitmer, Michihiro Hayashi, Christine Fox, Carlos O. Esquivel, Olivia M. Martinez CD8+ cells are not necessary for allograft rejection or the induction of apoptosis in an experimental model of small intestinal transplantation. Krams SM, Hayashi M, Fox CK, Villanueva JC, Whitmer KJ, Burns W, Esquivel CO, Martinez OM Human hepatocytes produce an isoform of FAS that inhibits apoptosis. Krams SM, Fox CK, Beatty PR, Cao S, Villanueva JC, Esquivel CO, Martinez OM
