Publications

Reduced TBX5 dosage undermines developmental control of atrial cardiomyocyte identity in a model of human atrial disease.

Kathiriya IS, Rao KS, Clark AP, Hu KM, Grant ZL, Matthews MN, Chen Z, Hota SK, Saucerman JJ, Bruneau BG

Development (Cambridge, England)
. Jan 15, 2026
A disrupted compartment boundary underlies abnormal cardiac patterning and congenital heart defects.

Kathiriya IS, Dominguez MH, Rao KS, Muncie-Vasic JM, Devine WP, Hu KM, Hota SK, Garay BI, Quintero D, Goyal P, Matthews MN, Thomas R, Sukonnik T, Miguel-Perez D, Winchester S, Brower EF, Forjaz A, Wu PH, Wirtz D, Kiemen AL, Bruneau BG

Nature cardiovascular research
. Dec 29, 2025
Author Correction: Brahma safeguards canalization of cardiac mesoderm differentiation.

Hota SK, Rao KS, Blair AP, Khalilimeybodi A, Hu KM, Thomas R, So K, Kameswaran V, Xu J, Polacco BJ, Desai RV, Chatterjee N, Hsu A, Muncie JM, Blotnick AM, Winchester SAB, Weinberger LS, Hüttenhain R, Kathiriya IS, Krogan NJ, Saucerman JJ, Bruneau BG

Nature
. Dec 1, 2025
Reduced TBX5 dosage undermines developmental control of atrial cardiomyocyte identity in a model of human atrial disease.

Kathiriya IS, Rao KS, Clark AP, Hu KM, Grant ZL, Matthews MN, Chen Z, Saucerman JJ, Hota SK, Bruneau BG

bioRxiv : the preprint server for biology
. Aug 19, 2025
Dose-dependent sensitivity of human 3D chromatin to a heart disease-linked transcription factor.

Grant ZL, Kuang S, Zhang S, Horrillo AJ, Rao KS, Kameswaran V, Joubran C, Lau PK, Dong K, Yang B, Bartosik WM, Zemke NR, Ren B, Kathiriya IS, Pollard KS, Bruneau BG

bioRxiv : the preprint server for biology
. Jan 12, 2025
In preprints: insights into human heart development and congenital heart defects.

Kathiriya IS

Development (Cambridge, England)
. Aug 15, 2024
A single institution anesthetic experience with catheterization of pediatric pulmonary hypertension patients.

Morell E, Colglazier E, Becerra J, Stevens L, Steurer MA, Sharma A, Nguyen H, Kathiriya IS, Weston S, Teitel D, Keller R, Amin EK, Nawaytou H, Fineman JR

Pulmonary circulation
. Apr 12, 2024
A TBX5-dependent compartment boundary patterns the cardiac interventricular septum.

Kathiriya IS, Dominguez MH, Rao KS, Muncie-Vasic JM, Patrick Devine W, Hu KM, Hota SK, Garay BI, Quintero D, Goyal P, Matthews MN, Thomas R, Sukonnik T, Miguel-Perez D, Winchester S, Brower EF, Forjaz A, Wu PH, Wirtz D, Kiemen AL, Bruneau BG

bioRxiv : the preprint server for biology
. Feb 5, 2024
Cell Layers: uncovering clustering structure in unsupervised single-cell transcriptomic analysis.

Blair AP, Hu RK, Farah EN, Chi NC, Pollard KS, Przytycki PF, Kathiriya IS, Bruneau BG

Bioinformatics advances
. Aug 4, 2022
Brahma safeguards canalization of cardiac mesoderm differentiation.

Hota SK, Rao KS, Blair AP, Khalilimeybodi A, Hu KM, Thomas R, So K, Kameswaran V, Xu J, Polacco BJ, Desai RV, Chatterjee N, Hsu A, Muncie JM, Blotnick AM, Winchester SAB, Weinberger LS, Hüttenhain R, Kathiriya IS, Krogan NJ, Saucerman JJ, Bruneau BG

Nature
. Jan 26, 2022