Publications

Activation of Toll-like receptor 2 impairs hypoxic pulmonary vasoconstriction in mice.

Petersen B, Bloch KD, Ichinose F, Shin HS, Shigematsu M, Bagchi A, Zapol WM, Hellman J

American journal of physiology. Lung cellular and molecular physiology
. Nov 30, 2007
MyD88-dependent immune activation mediated by human immunodeficiency virus type 1-encoded Toll-like receptor ligands.

Meier A, Alter G, Frahm N, Sidhu H, Li B, Bagchi A, Teigen N, Streeck H, Stellbrink HJ, Hellman J, van Lunzen J, Altfeld M

Journal of virology
. May 16, 2007
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein.

Whorton MR, Bokoch MP, Rasmussen SG, Huang B, Zare RN, Kobilka B, Sunahara RK

Proceedings of the National Academy of Sciences of the United States of America
. Apr 23, 2007
Toll-like receptor 2 activation by bacterial peptidoglycan-associated lipoprotein activates cardiomyocyte inflammation and contractile dysfunction.

Zhu X, Bagchi A, Zhao H, Kirschning CJ, Hajjar RJ, Chao W, Hellman J, Schmidt U

Critical Care Medicine
. Mar 1, 2007
MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists.

Bagchi A, Herrup EA, Warren HS, Trigilio J, Shin HS, Valentine C, Hellman J

Journal of immunology (Baltimore, Md. : 1950)
. Jan 15, 2007
Passive immunization to outer membrane proteins MLP and PAL does not protect mice from sepsis.

Valentine CH, Hellman J, Beasley-Topliffe LK, Bagchi A, Warren HS

Molecular medicine (Cambridge, Mass.)
. Sep 1, 2006
Cytochrome c conformations resolved by the photon counting histogram: watching the alkaline transition with single-molecule sensitivity.

Perroud TD, Bokoch MP, Zare RN

Proceedings of the National Academy of Sciences of the United States of America
. Nov 28, 2005
Increased leakage of sarcoplasmic reticulum Ca2+ contributes to abnormal myocyte Ca2+ handling and shortening in sepsis.

Zhu X, Bernecker OY, Manohar NS, Hajjar RJ, Hellman J, Ichinose F, Valdivia HH, Schmidt U

Critical Care Medicine
. Mar 1, 2005
Bacterial peptidoglycan-associated lipoprotein: a naturally occurring toll-like receptor 2 agonist that is shed into serum and has synergy with lipopolysaccharide.

Liang MD, Bagchi A, Warren HS, Tehan MM, Trigilio JA, Beasley-Topliffe LK, Tesini BL, Lazzaroni JC, Fenton MJ, Hellman J

The Journal of infectious diseases
. Feb 8, 2005
Protective efficacy of CAP18106-138-immunoglobulin G in sepsis.

Warren HS, Matyal R, Allaire JE, Yarmush D, Loiselle P, Hellman J, Paton BG, Fink MP

The Journal of infectious diseases
. Oct 20, 2003