Publications

A journey upstream: Fluctuating platelet-specific genes in cell-free plasma as proof-of-concept for using ribonucleic acid sequencing to improve understanding of postinjury platelet biology.

Kornblith LZ, Bainton CMV, Fields AT, Matthay ZA, Magid NT, Nunez-Garcia B, Prakash A, Kurien PA, Callcut RA, Cohen MJ, Bainton RJ

The journal of trauma and acute care surgery
. Jun 1, 2020
TIMELESS mutation alters phase responsiveness and causes advanced sleep phase.

Kurien P, Hsu PK, Leon J, Wu D, McMahon T, Shi G, Xu Y, Lipzen A, Pennacchio LA, Jones CR, Fu YH, Ptácek LJ

Proceedings of the National Academy of Sciences of the United States of America
. May 28, 2019
Elevated Gut Microbiome-Derived Propionate Levels Are Associated With Reduced Sterile Lung Inflammation and Bacterial Immunity in Mice.

Tian X, Hellman J, Horswill AR, Crosby HA, Francis KP, Prakash A

Frontiers in microbiology
. Feb 14, 2019
Activation of orexin system facilitates anesthesia emergence and pain control.

Zhou W, Cheung K, Kyu S, Wang L, Guan Z, Kurien PA, Bickler PE, Jan LY

Proceedings of the National Academy of Sciences of the United States of America
. Oct 22, 2018
Evolutionarily Conserved Roles for Blood-Brain Barrier Xenobiotic Transporters in Endogenous Steroid Partitioning and Behavior.

Hindle SJ, Munji RN, Dolghih E, Gaskins G, Orng S, Ishimoto H, Soung A, DeSalvo M, Kitamoto T, Keiser MJ, Jacobson MP, Daneman R, Bainton RJ

Cell reports
. Oct 31, 2017
NLRP3 Inflammasome Mediates Dormant Neutrophil Recruitment following Sterile Lung Injury and Protects against Subsequent Bacterial Pneumonia in Mice.

Tian X, Sun H, Casbon AJ, Lim E, Francis KP, Hellman J, Prakash A

Frontiers in immunology
. Oct 31, 2017
N-Arachidonoyl Dopamine Modulates Acute Systemic Inflammation via Nonhematopoietic TRPV1.

Lawton SK, Xu F, Tran A, Wong E, Prakash A, Schumacher M, Hellman J, Wilhelmsen K

Journal of immunology (Baltimore, Md. : 1950)
. Jul 12, 2017
Lung Ischemia-Reperfusion is a Sterile Inflammatory Process Influenced by Commensal Microbiota in Mice.

Prakash A, Sundar SV, Zhu YG, Tran A, Lee JW, Lowell C, Hellman J

Shock (Augusta, Ga.)
. Sep 1, 2015
Extracellular signal-regulated kinase 5 promotes acute cellular and systemic inflammation.

Wilhelmsen K, Xu F, Farrar K, Tran A, Khakpour S, Sundar S, Prakash A, Wang J, Gray NS, Hellman J

Science signaling
. Aug 25, 2015
Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS.

Kangelaris KN, Prakash A, Liu KD, Aouizerat B, Woodruff PG, Erle DJ, Rogers A, Seeley EJ, Chu J, Liu T, Osterberg-Deiss T, Zhuo H, Matthay MA, Calfee CS

American journal of physiology. Lung cellular and molecular physiology
. Mar 20, 2015