Publications

Optimal Vasopressin Initiation in Septic Shock: The OVISS Reinforcement Learning Study.

Kalimouttou A, Kennedy JN, Feng J, Singh H, Saria S, Angus DC, Seymour CW, Pirracchio R

JAMA
. May 20, 2025
Iloprost for the Treatment of Severe Septic Shock with Persistent Hypoperfusion: A Double-Blind, Randomized Controlled Trial.

Legrand M, Jullien E, Kimmoun A, Geri G, Ait-Oufella H, Abrard S, Gaugain S, Bounes F, Guerci P, Pottecher J, Jamme M, Poncelin de Raucourt Y, Barraud D, Constantin JM, Juguet W, Lasocki S, Sonneville R, Audibert J, Plantefève G, Ellrodt O, Fedou AL, Leone M, Lefebvre L, Auvet A, Chen D, Vicaut E, Dépret F, I-MICRO trial investigators

American journal of respiratory and critical care medicine
. May 19, 2025
Evaluating the risks and benefits of continuing versus withholding renin-angiotensin system inhibitors: a systematic review and meta-analysis with trial sequential analysis.

Shalabi L, Ibrahim A, Zreigh S, Rifai M, Ramadan S, Arafa MA, Mustafa OM, Ansab M, Krayem MF, Elsabbagh I, Mash'al NH, Waleed S, Legrand M

BJA open
. May 3, 2025
Postoperative Outcomes Among Sodium-Glucose Cotransporter 2 Inhibitor Users.

Tallarico RT, Jing B, Lu K, Chawla SA, Luo Y, Badathala A, Chen CL, Wallace AW, Legrand M

JAMA surgery
. Apr 30, 2025
Therapeutic Potential of Centhaquine Citrate, a Selective Alpha-2B Adrenoceptor Agonist, in the Management of Circulatory Shock.

Legrand M, Ranjan A, Rammohan S, De Backer D, Ostermann M, Gulati A, Vincent JL, Khanna AK

Drugs
. Apr 20, 2025
Open Access Dataset and Common Data Model for Pulse Oximeter Performance Data.

Fong N, Lipnick MS, Behnke E, Chou Y, Elmankabadi S, Ortiz L, Almond CS, Auchus I, Burnett GW, Bisegerwa R, Conrad DR, Hendrickson CM, Hooli S, Kopotic R, Leeb G, Martin D, McCollum ED, Monk EP, Moore KL, Shmuylovich L, Scott JB, Wong AI, Zhou T, Pirracchio R, Bickler PE, Feiner J, Law TJ

Scientific data
. Apr 3, 2025
Alterations in the renin-angiotensin system during septic shock.

Benaroua C, Pucci F, Rooman M, Picod A, Favory R, Legrand M, Vincent JL, Creteur J, Taccone FS, Annoni F, Garcia B

Annals of intensive care
. Mar 24, 2025
Advancing surgical outcomes through cardiovascular biomarker sub-phenotyping.

Garcia B, Khanna AK, Legrand M

British journal of anaesthesia
. Mar 14, 2025
Cardiac index-guided haemodynamic management and myocardial injury after hepatopancreatic surgery.

Boulos N, Delaporte A, Legrand M, Saugel B, Joosten A

European journal of anaesthesiology
. Mar 5, 2025
Expanding the role of PoCUS in tailoring diuretic strategies for congestion management in critical care: authors' reply.

Ostermann M, Awdishu L, Legrand M

Intensive care medicine
. Feb 27, 2025