Kolodzie Lab

About

Welcome to Dr. Kerstin Kolodzie's Perioperative Clinical Research Group

As physician scientist, my goal is to improve outcomes after surgery. I design, conduct, and analyze clinical research studies that are intended to optimize patient care, starting with the preparation for surgery and extending through to the entire postoperative period. I have worked in areas such as postoperative pain after orthopedic surgery and postoperative nausea and vomiting.

More recently, my work has centered on patients undergoing kidney transplantation. In the Unites States, the number of patients listed for kidney transplantation dramatically exceeds the number of organs available. This organ shortage mandates research to understand and avoid suboptimal outcomes after transplant. Relevant outcomes do not only include the function of the transplanted organ. I am specifically interested in measures to improve overall health, well-being and quality of life after kidney transplantation. 

 

 

Current Research Projects

Association of Skeletal Muscle Mass with Early Postoperative Complications and Patient-reported Recovery in Patients Undergoing Kidney Transplantation – A Cohort Study (PI)

The Effect of Normal Saline Solution Administered Perioperatively on Delayed Graft Function in Patients Undergoing Kidney Transplantation – A Cohort Study (PI)

Intravenous Fluid Management Practices in Kidney Transplant Patients: A Multicenter Observational Cohort Study (center PI)

People

 

 

Kerstin Kolodzie, MD, PhD, MAS

I am board certified in Anesthesiology and Emergency Medicine in Germany. Originating from Hamburg, I joined the Perioperative Clinical Research Core, Department of Anesthesia & Perioperative Care at UCSF from 2007 to 2009 as a research fellow. Since then, I have researched perioperative outcomes in several areas such as postoperative pain after orthopedic surgery and postoperative nausea and vomiting. To further improve my skills and knowledge I completed a Master’s Degree program of Advanced Studies (MAS) in Clinical Research in 2019. I perform evidence based quantitative systematic reviews, epidemiological research, and controlled clinical trials. Concomitantly, I hold a full faculty appointment as Associate Professor of Anesthesia in the Department of Anesthesia & Perioperative Care at UCSF since 2007. In my clinical practice, I am specialized in regional anesthesia and anesthesia for orthopedic surgery.
Contact: [email protected]

Özlem S. Çakmakkaya, MD, PhD

Dr. Ӧzlem S. Cakmakkaya is an Associate Professor of Anesthesiology in Istanbul/Turkey. She is specialized in pediatric anesthesia. From 2007 to 2009 she joined the Perioperative Clinical Research Core, Dept. of Anesthesia at UCSF as a clinical research fellow. In addition, she earned a PhD degree in Medical Education from the University of Ege, Turkey. Her area of expertise is data management, statistical data analysis and meta-analysis. Dr. Cakmakkaya's expertise in biostatistics makes her a valued resource for the research group and we continue to collaborate on several projects such as systematic reviews and data analysis.

Currrently, Dr. Cakmakkaya holds a faculty position at the Department of Medical Education, University of Istanbul-Cerrahpasa, Cerrahpasa Medical School and serves as the Chair of the Department.

 

Alice Roberts 

Ms. Roberts holds a Masters of Arts in Anthropology and a Certificate in Editing from UC Berkeley. She began working with Dr. Kolodzie in 2007 as a member of the Perioperative Clinical Research Core. She has over ten years experience as a medical editor and writer and has worked on a variety of research projects. She currently acts as the medical writer and editor for Dr. Kolodzie’s lab.

 

Sakura Kinjo, MD 

Visit her lab here

 

 

Publications
  1. Chen A, Kolodzie K, Schultz A, Hansen EN, Braehler M. Continuous Lumbar Plexus Block vs Continuous Lumbar Erector Spinae Plane Block for Postoperative Pain Control After Revision Total Hip Arthroplasty. Arthroplast Today. 2021 Jun; 9:29-34. PMID: 33997205.
    View in: PubMed
  2. Cakmakkaya OS, Bati AH, Kolodzie K. Correction: Cross-cultural adaptation of the Fresno Test for Turkish language. PLoS One. 2021; 16(4):e0250835. PMID: 33886691.
    View in: PubMed
  3. Extraplexus versus intraplexus ultrasound-guided interscalene brachial plexus block for ambulatory arthroscopic shoulder surgery: A randomized controlled trial. PLoS One. 2021; 16(2):e0246792. PMID: 33600437.
    View in: PubMed
  4. Cakmakkaya OS, Bati AH, Kolodzie K. Cross-cultural adaptation of the Fresno Test for Turkish language. PLoS One. 2021; 16(1):e0245195. PMID: 33417622.
    View in: PubMed
  5. Efune GE, Zerillo J, Zhou G, Mazzeffi MA, Demaria S, Wang C. Intravenous Fluid Management Practices in Kidney Transplant Patients: A Multicenter Observational Cohort Pilot Study. Semin Cardiothorac Vasc Anesth. 2020 Sep; 24(3):256-264.
  6. Kinjo S, Kolodzie K, Dong K, Zhang AL. The effects of transmuscular quadratus lumborum blocks on postoperative pain in arthroscopic hip surgery: a cohort analysis. J Anesth. 2019 Jul 01. PMID: 31264111.
    View in: PubMed
  7. Behrends M, Yap EN, Zhang AL, Kolodzie K, Kinjo S, Harbell MW, Aleshi P. Preoperative Fascia Iliaca Block Does Not Improve Analgesia after Arthroscopic Hip Surgery, but Causes Quadriceps Muscles Weakness: A Randomized, Double-blind Trial. Anesthesiology. 2018 09; 129(3):536-543. PMID: 29975203.
    View in: PubMed 
  8. Fernandez-Bustamante A, Frendl G, Sprung J, Kor DJ, Subramaniam B, Martinez Ruiz R, Lee JW, Henderson WG, Moss A, Mehdiratta N, Colwell MM, Bartels K, Kolodzie K, Giquel J, Vidal Melo MF. Postoperative Pulmonary Complications, Early Mortality, and Hospital Stay Following Noncardiothoracic Surgery: A Multicenter Study by the Perioperative Research Network Investigators. JAMA Surg. 2017 02 01; 152(2):157-166. PMID: 27829093.
    View in: PubMed 
  9. Harbell MW, Cohen JM, Kolodzie K, Behrends M, Braehler MR, Kinjo S, Feeley BT, Aleshi P. Combined preoperative femoral and sciatic nerve blockade improves analgesia after anterior cruciate ligament reconstruction: a randomized controlled clinical trial. J Clin Anesth. 2016 Sep; 33:68-74. PMID: 27555136.
    View in: PubMed
  10. Cakmakkaya OS, Kolodzie K, Apfel CC, Pace NL. Anaesthetic techniques for risk of malignant tumour recurrence. Cochrane Database Syst Rev. 2014 Nov 07; (11):CD008877. PMID: 25379840.
    View in: PubMed 
  11. Cohen JM, Kolodzie K, Shah S, Aleshi P.Preoperative Sciatic and Femoral Nerve Blocks for Anterior Cruciate Ligament Reconstruction: A Retrospective Analysis. Journal of Anesthesia & Clinical Research. 2014; (5: 452).
    View Publication
  12. Ruschulte H, Shi S, Tseng WW, Kolodzie K, Crawford PC, Schneider DB, Kashani-Sabet M, Minor D, Apfel C, Leong SP. Anesthesia management of patients undergoing hyperthermic isolated limb perfusion with melphalan for melanoma treatment: an analysis of 17 cases. BMC Anesthesiol. 2013 Jul 17; 13(1):15. PMID: 23865420.
    View in: PubMed 
  13. Fiege M, Weisshorn R, Kolodzie K, Wappler F, Gerbershagen MU. Effects of theophylline on anesthetized malignant hyperthermia-susceptible pigs. J Biomed Biotechnol. 2011; 2011:937479. PMID: 22131820. 
    View in: PubMed 
  14. Kolodzie K, Apfel CC. Nausea and vomiting after office-based anesthesia. Curr Opin Anaesthesiol. 2009 Aug; 22(4):532-8. PMID: 19512914.
    View in: PubMed
  15. Apfel CC, Cakmakkaya OS, Frings G, Kranke P, Malhotra A, Stader A, Turan A, Biedler A, Kolodzie K. Droperidol has comparable clinical efficacy against both nausea and vomiting. Br J Anaesth. 2009 Sep; 103(3):359-63. PMID: 19605409.
    View in: PubMed 
  16. Radke OC, Biedler A, Kolodzie K, Cakmakkaya OS, Silomon M, Apfel CC. The effect of postoperative fasting on vomiting in children and their assessment of pain. Paediatr Anaesth. 2009 May; 19(5):494-9. PMID: 19453581.
    View in: PubMed 
  17. Gerbershagen MU, Fiege M, Weisshorn R, Kolodzie K, Schulte am Esch J, Wappler F. Cumulative and bolus in vitro contracture testing with 4-chloro-3-ethylphenol in malignant hyperthermia positive and negative human skeletal muscles. Anesth Analg. 2005 Sep; 101(3):710-4, table of contents. PMID: 16115979.
    View in: PubMed 
  18. Fiege M, Wappler F, Weisshorn R, Gerbershagen MU, Kolodzie K, Schulte am Esch J. Phosphodiesterase-III-inhibition with amrinone leads to contracture development in skeletal muscle preparations of malignant hyperthermia susceptible swine. Eur J Anaesthesiol. 2005 Apr; 22(4):283-8. PMID: 15892406.
    View in: PubMed 
  19. Gerbershagen MU, Wappler F, Fiege M, Weihorn R, Kolodzie K, Schulte Esch J. Inhibition of sarcoplasmic Ca2+ adenosine triphosphatase in porcine skeletal muscle samples with cyclopiazonic acid enables in vitro malignant hyperthermia discrimination. Anesthesiology. 2004 Dec; 101(6):1475-7. PMID: 15564960.
    View in: PubMed 
  20. Weisshorn R, Wappler F, Fiege M, Gerbershagen MU, Kolodzie K, Alberts P, Horn EP, Schulte Am Esch J. Ryanodine contracture threshold times for diagnosis of malignant hyperthermia susceptibility: an experimental approach from a single laboratory. J Clin Anesth. 2004 Aug; 16(5):353-7. PMID: 15374556.
    View in: PubMed 
  21. Gerbershagen MU, Fiege M, Weisshorn R, Kolodzie K, Wappler F. [Theophylline induces contractures in porcine skeletal muscle preparations with the disposition to malignant hyperthermia]. Anasthesiol Intensivmed Notfallmed Schmerzther. 2004 Mar; 39(3):147-52. PMID: 15042504.
    View in: PubMed 
  22. Gerbershagen MU, Wappler F, Fiege M, Weisshorn R, Kolodzie K, Schulte am Esch J. [Is a presymptomatic malignant hyperthermia in-vitro diagnosis with 4-chloro-3-ethyl phenol possible? A study using porcine skeletal preparations]. Anasthesiol Intensivmed Notfallmed Schmerzther. 2004 Feb; 39(2):81-6. PMID: 14767797. 
    View in: PubMed 
  23. Gerbershagen MU, Wappler F, Fiege M, Kolodzie K, Weisshorn R, Szafarczyk W, Kudlik C, Schulte Am Esch J. Effects of a 5HT(2) receptor agonist on anaesthetized pigs susceptible to malignant hyperthermia. Br J Anaesth. 2003 Aug; 91(2):281-4. PMID: 12878630.
    View in: PubMed 
  24. Fiege M, Wappler F, Weisshorn R, Gerbershagen MU, Kolodzie K, Schulte Am Esch J. In vitro and in vivo effects of the phosphodiesterase-III inhibitor enoximone on malignant hyperthermia-susceptible swine. Anesthesiology. 2003 Apr; 98(4):944-9. PMID: 12657857.
    View in: PubMed
  25. Wappler F, Scholz J, Fiege M, Kolodzie K, Kudlik C, Weisshorn R, Schulte am Esch J. 4-chloro-m-cresol is a trigger of malignant hyperthermia in susceptible swine. Anesthesiology. 1999 Jun; 90(6):1733-40. PMID: 10360873.
    View in: PubMed